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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 985Generated: October 24, 2026

1-[4-[(4-Fluorophenyl)methyl]phenyl]piperazine → 5-[4-(4-(4-(4-Fluorophenyl)methylphenyl)piperazin-1-yl)butyryl]-2,3,4,5-tetrahydro-1,5-benzoxazepine

https://huagongshe.com/en/reaction/985

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[4-[(4-Fluorophenyl)methyl]phenyl]piperazineHCID 1519998—
Reactant5-(4-Chlorobutyryl)-2,3,4,5-tetrahydro-1,5-benzoxazepineHCID 19694250—
Product5-[4-(4-(4-(4-Fluorophenyl)methylphenyl)piperazin-1-yl)butyryl]-2,3,4,5-tetrahydro-1,5-benzoxazepineHCID 19694245—

Reaction Steps

The compound (16) synthesized in Reference Example 16 and the compound (5) synthesized in Reference Example 5 were used to produce the above compound in the same way as Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05723475
Source datasetuspto-grants-1998_03
ORD IDord-eb6b76f4e5d04dfb88c2dcb703a6d60d
Source noteuspto-grants-1998_03