Propyl 4-chloro-3-oxobutanoate → HCID 18610889, compound
Reaction equation
[CH2:1]([O:4][C:5](=[O:11])[CH2:6][C:7]([CH2:9][Cl:10])=[O:8])[CH2:2][CH3:3]>C(Cl)(Cl)Cl>[CH2:1]([O:4][C:5](=[O:11])[CH2:6][C@@H:7]([OH:8])[CH2:9][Cl:10])[CH2:2][CH3:3]Participants
3
Reagents, catalysts & solvents 1
Procedure
The procedure of example 375 was repeated using n-propyl-4-chloroacetoacetate as the substrate to afford n-propyl-4-chloro-3(R)-hydroxybutyrate, [α]D23 +21.5° (c, 5.0, CHCl3).
Sources & evidence
- ORD record
- ord-e9a4bc784082418eb1c7bd42633ec3f4
- Source dataset
- uspto-grants-1987_12
- Patent number
- US04710468
Reaction notes
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