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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 986Generated: October 26, 2026

4-[4-(4-Fluorophenyl)methylphenyl]piperidine → 5-[4-(4-(4-(4-Fluorophenyl)methylphenyl)piperidin-1-yl)butyryl]-2,3,4,5-tetrahydro-1,5-benzoxazepine

https://huagongshe.com/reaction/986

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[4-(4-Fluorophenyl)methylphenyl]piperidineHCID 15462120—
Reactant5-(4-Chlorobutyryl)-2,3,4,5-tetrahydro-1,5-benzoxazepineHCID 19694250—
Product5-[4-(4-(4-(4-Fluorophenyl)methylphenyl)piperidin-1-yl)butyryl]-2,3,4,5-tetrahydro-1,5-benzoxazepineHCID 19694273—

Reaction Steps

The compound (16) synthesized in Reference Example 16 and the compound (7) synthesized in Reference Example 7 were used to produce the above compound in the same way as Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05723475
Source datasetuspto-grants-1998_03
ORD IDord-1255beb210e449d39ea430d3d1fca98e
Source noteuspto-grants-1998_03