Methanol → Methyl 3-(3-bromophenyl)prop-2-enoate

HRID 986543

Reaction equation

[Br:1][C:2]1[CH:3]=[C:4]([CH:10]=[CH:11][CH:12]=1)[CH:5]=[CH:6][C:7]([OH:9])=[O:8].[CH3:13]O>>[Br:1][C:2]1[CH:3]=[C:4]([CH:10]=[CH:11][CH:12]=1)[CH:5]=[CH:6][C:7]([O:9][CH3:13])=[O:8]

Participants

Reactant 2

HCID 887Methanol

HCID 362513-(3-Bromophenyl)acrylic acid

Product 1

HCID 610698Methyl 3-(3-bromophenyl)prop-2-enoateYield 81%

Procedure

Reaction of 3-bromocinnamic acid (22.72 g) with methyl lodide (21.3 g) as described in Example 1 gave the title ester (19.5 g, 81%) as a white solid mp (methanol) 62°-65° C.

Sources & evidence

ORD record: ord-b7f362e3364b4862b14137fe333145c8
Source dataset: uspto-grants-1987_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04713486

Linked notes

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