2-Bromo-N-phenylacetamide → N-phenyl-4-(4-phenoxyphenyl)-1-piperidinacetamide

HRID 988

Reaction equation

HRID 988 reaction equation
[O:1]([C:8]1[CH:13]=[CH:12][C:11]([CH:14]2[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]2)=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:20]1([NH:26][C:27](=[O:30])[CH2:28]Br)[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[C:20]1([NH:26][C:27](=[O:30])[CH2:28][N:17]2[CH2:18][CH2:19][CH:14]([C:11]3[CH:12]=[CH:13][C:8]([O:1][C:2]4[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=4)=[CH:9][CH:10]=3)[CH2:15][CH2:16]2)[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 948182-Bromo-N-phenylacetamideHCID 110759844-(4-Phenoxyphenyl)piperidine

Product 1

HCID 19694260N-phenyl-4-(4-phenoxyphenyl)-1-piperidinacetamide

Procedure

The compound (4) synthesized in Reference Example 4 and the compound (23) synthesized in Reference Example 23 were used to produce the above compound in the same way as Example 1.

Workup

  1. customto produce the above compound in the same way as Example 1

Sources & evidence

ORD record
ord-06001c8a7a0d41e09c2cfab5cdeefd53
Source dataset
uspto-grants-1998_03
Patent number
US05723475

Linked notes

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