1-Methylimidazole → HCID 178480833, compound

HRID 988922

Reaction equation

[Cl:1][CH2:2][C:3]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[CH:6]=[CH:5][C:4]=1[OH:12].[CH3:13][N:14]1[CH:18]=[CH:17][N:16]=[CH:15]1>>[Cl-:1].[OH:12][C:4]1[CH:5]=[CH:6][C:7]([N+:9]([O-:11])=[O:10])=[CH:8][C:3]=1[CH2:2][N+:16]1[CH:17]=[CH:18][N:14]([CH3:13])[CH:15]=1

Participants

Reactant 2

HCID 13901-Methylimidazole

HCID 763052-(Chloromethyl)-4-nitrophenol

Product 1

HCID 178480833HCID 178480833, compound

Procedure

Starting with 56.3 g (0.3 mol) of 2-chloromethyl-4-nitrophenol and 29.6 g (0.36 mol) of 1-methyl-1H-imidazole, 65.1 g of yellow crystals melting with decomposition at 250-260° C. (Kofler) were obtained, the elemental analysis of which, calculated for C11H12N3O3Cl, was:

Workup

custommelting with decomposition at 250-260° C.
customwere obtained

Sources & evidence

ORD record: ord-391f7cbd9dc9464c92cb7445eab0dc17
Source dataset: uspto-grants-2003_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06638321B1

Linked notes

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