Sodium chloride; water → Methyl Palmitate

HRID 988927

Reaction equation

HRID 988927 reaction equation
O.[Na+].[Cl-].CN1[C@@H]2C[C@@H:11]([O:13][C:14]([CH:16]([C:19]3[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=3)CO)=[O:15])C[C@H]1CC2>>[C:14]([O:13][CH3:11])(=[O:15])[CH2:16][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:14][CH2:16][CH2:19][CH2:24][CH2:23][CH2:22][CH2:21][CH3:20]

Participants

3

Reactant 2

HCID 57417360Sodium chloride; waterHCID 178481186HCID 178481186, compound

Product 1

HCID 8181Methyl Palmitate

Procedure

Basal gastric acidity was determined by pyloric ligation under ether anaesthesia followed by gastric lavage with normal saline. Except for the control group, all the rats received 3 doses (1, 3 & 5 mg/kg) of the said compound and standard antagonist atropine (0.01, 0.05 & 0.1 mg/kg) subcutaneously 15 minutes prior to pyloric ligation. Three hours later the animals were killed and the stomach was tied at the oesophageal junction and removed. The contents were collected by cutting along the greater curvature and the free acidity was determined by titration against 0.01 normal NaOH using Topfers reagent as indicator.

Workup

  1. customThree hours
  2. customremoved
  3. customThe contents were collected

Sources & evidence

ORD record
ord-a17a817f1e9a426993b4306d25f81cd1
Source dataset
uspto-grants-2003_10
Patent number
US06638546B2

Linked notes

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