Bromide ion → 1H-Imidazolium, 2-fluoro-4,5-dihydro-1,3-dimethyl-, bromide (1:1)
Reaction equation
[Br-:1].[Na+].[F:3][CH:4]1[N:8]([CH3:9])[CH2:7][CH2:6][NH+:5]1[CH3:10].[Br-]>C(#N)C>[Br-:1].[F:3][CH:4]1[N:8]([CH3:9])[CH2:7][CH2:6][NH+:5]1[CH3:10]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
To a 300 ml four necked flask, 13.78 g (0.101 mol) of 2,2-difluoro-1,3-dimethylimidazolidine(DFI), 10.25 g (0.0995 mol) of sodium bromide, and 126.5 g of acetonitrile were charged and reacted at 25° C. for 4 hours in a nitrogen atmosphere. The yield of 2-fluoro-1,3-dimethylimidazolinium=bromide was 99%.
Workup
- customreacted at 25° C. for 4 hours in a nitrogen atmosphere
Sources & evidence
- ORD record
- ord-2df5af123f8745dfa1241a1479d596b1
- Source dataset
- uspto-grants-2002_10
- Patent number
- US06458990B1
Reaction notes
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