4-Oxo-2,4,6,7-tetrahydropyrano[3,4-C]pyrrole-1-carbaldehyde → 1-(5-Bromo-4-methyl-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-6,7-dihydro-2H-pyrano[3,4-c]pyrrol-4-one
Reaction equation
[Br:1][C:2]1[C:3]([CH3:12])=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[CH2:5]2.[O:13]=[C:14]1[C:19]2=[CH:20][NH:21][C:22]([CH:23]=O)=[C:18]2[CH2:17][CH2:16][O:15]1>>[Br:1][C:2]1[C:3]([CH3:12])=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[C:5]2=[CH:23][C:22]1[NH:21][CH:20]=[C:19]2[C:14](=[O:13])[O:15][CH2:16][CH2:17][C:18]=12Participants
3
Procedure
5-Bromo-4-methyl-1,3-dihydro-indol-2-one was condensed with 4-oxo-2,4,6,7-tetrahydro-pyrano[3,4-c]pyrrole-1-carbaldehyde to give the title compound.
Sources & evidence
- ORD record
- ord-c7f9dee25e414471bf04eba0ffba832b
- Source dataset
- uspto-grants-2002_10