HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylbenzene → 1-Phenylethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylbenzene | HCID 7500 | — |
| Reactant | N-Hydroxyphthalimide | HCID 10665 | — |
| Reactant | Nitric Oxide | HCID 145068 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 1-Phenylethanol | HCID 7409 | 18% |
| Product | 1-Nitroethylbenzene | HCID 23618 | 14% |
Reaction Steps
Into a flask, 1 mmole of ethylbenzene, 0.05 mmole of N-hydroxyphthalimide and 5 ml of acetic acid were added to mix and the flask was equipped with a gas bag (about 1L)of nitrogen monoxide NO. The mixture was reacted for 8 hours at 100° C. with stirring. The reaction products were analyzed by gas chromatography, and, as a result, the conversion of ethylbenzene was 85%, and 1-nitroethylbenzene (yield 14%), 1-hydroxyethylbenzene (yield 18%) and 1-acetyloxyethylbenzene (yield 30%) were formed.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06468487B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-c458f446724549468ddfe965d5681074 |
| Source note | uspto-grants-2002_10 |