4-Chloro-6-methyl-2-(pyridin-2-yl)pyrimidine → 4-(4-Fluoro-3-methoxyanilino)-6-methyl-2-(2-pyridinyl)pyrimidine

HRID 99574

Reaction equation

HRID 99574 reaction equation
[Cl:1][c:2]1[n:3][c:4](-[c:9]2[n:10][cH:11][cH:12][cH:13][cH:14]2)[n:5][c:6]([CH3:8])[cH:7]1.[F:15][c:16]1[c:17]([O:23][CH3:24])[cH:18][c:19]([NH2:20])[cH:21][cH:22]1>>[c:2]1([NH:20][c:19]2[cH:18][c:17]([O:23][CH3:24])[c:16]([F:15])[cH:22][cH:21]2)[n:3][c:4](-[c:9]2[n:10][cH:11][cH:12][cH:13][cH:14]2)[n:5][c:6]([CH3:8])[cH:7]1

Participants

3

Reactant 2

HCID 27633954-Chloro-6-methyl-2-(pyridin-2-yl)pyrimidineHCID 27745334-Fluoro-3-methoxyaniline

Product 1

HCID 227323624-(4-Fluoro-3-methoxyanilino)-6-methyl-2-(2-pyridinyl)pyrimidine

Sources & evidence

ORD record
ord-e1a714d0a0bc42218000a58c78bf5a01
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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