Dimethyl Sulfoxide → 1-[5-(4-Chlorophenyl)pyridin-2-yl]-4-(propan-2-yl)piperazine

HRID 99583

Reaction equation

HRID 99583 reaction equation
[CH3:15][S:16]([CH3:17])=[O:18].[CH:19]([CH3:20])([CH3:21])[N:22]1[CH2:23][CH2:24][NH:25][CH2:26][CH2:27]1.[Cl:1][c:2]1[n:3][cH:4][c:5](-[c:8]2[cH:9][cH:10][c:11]([Cl:14])[cH:12][cH:13]2)[cH:6][cH:7]1.[OH2:28]>>[c:2]1([N:25]2[CH2:24][CH2:23][N:22]([CH:19]([CH3:20])[CH3:21])[CH2:27][CH2:26]2)[n:3][cH:4][c:5](-[c:8]2[cH:9][cH:10][c:11]([Cl:14])[cH:12][cH:13]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 679Dimethyl SulfoxideHCID 962WaterHCID 780131-IsopropylpiperazineHCID 100365542-Chloro-5-(4-chlorophenyl)pyridine

Product 1

HCID 159513151-[5-(4-Chlorophenyl)pyridin-2-yl]-4-(propan-2-yl)piperazine

Sources & evidence

ORD record
ord-16cbc893405a45c6a21f231dc8c36346
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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