Ammonium → 1-(3-Methyl-isoquinolin-5-yl)-3-pyrrolidin-3-yl urea

Reaction equation

[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([NH:13][C:14](=[O:15])[NH:16][c:17]2[c:18]3[cH:19][c:20]([CH3:27])[n:21][cH:22][c:23]3[cH:24][cH:25][cH:26]2)[CH2:11][CH2:12]1.[CH3:32][OH:33].[CH:28]([O-:29])=[O:30].[Cl:34][CH2:35][Cl:36].[NH4+:31]>>[NH:8]1[CH2:9][CH:10]([NH:13][C:14](=[O:15])[NH:16][c:17]2[c:18]3[cH:19][c:20]([CH3:27])[n:21][cH:22][c:23]3[cH:24][cH:25][cH:26]2)[CH2:11][CH2:12]1

Participants

Reactant 5

HCID 223Ammonium

HCID 283Formate

HCID 887Methanol

HCID 6344Dichloromethane

HCID 104286221-(1-Benzyl-pyrrolidin-3-yl)-3-(3-methyl-isoquinolin-5-yl)urea

Product 1

HCID 688557451-(3-Methyl-isoquinolin-5-yl)-3-pyrrolidin-3-yl urea

Sources & evidence

ORD record: ord-42659e78cd3b4b66ba50d5543969adde
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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