Acetone → Methyl 3'-amino-4'-chloro-2-methylbiphenyl-4-carboxylate

HRID 99921

Reaction equation

HRID 99921 reaction equation
[Br:12][c:13]1[c:14]([CH3:23])[cH:15][c:16]([C:17](=[O:18])[O:19][CH3:20])[cH:21][cH:22]1.[C:24](=[O:25])([O-:26])[O-:27].[CH3:30][C:31](=[O:32])[CH3:33].[K+:28].[K+:29].[NH2:1][c:2]1[cH:3][c:4]([B:9]([OH:10])[OH:11])[cH:5][cH:6][c:7]1[Cl:8]>>[NH2:1][c:2]1[cH:3][c:4](-[c:13]2[c:14]([CH3:23])[cH:15][c:16]([C:17](=[O:18])[O:19][CH3:20])[cH:21][cH:22]2)[cH:5][cH:6][c:7]1[Cl:8]

Participants

6

Reactant 5

HCID 180AcetoneHCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 3294148Methyl 4-bromo-3-methylbenzoateHCID 43416433-Amino-4-chlorophenylboronic acid

Product 1

HCID 57704763Methyl 3'-amino-4'-chloro-2-methylbiphenyl-4-carboxylate

Sources & evidence

ORD record
ord-d14d3dcf08244cb59375d1054482db1a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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