Diethyl Ether → Tert-butyl 2-[2-(dibenzylamino)-1-hydroxy-3-phenylpropyl]-6-ethylpiperidine-1-carboxylate

HRID 99978

Reaction equation

HRID 99978 reaction equation
[C:6]([CH3:7])([CH3:8])([CH3:9])[O:10][C:11](=[O:12])[N:13]1[CH:14]([CH2:19][CH3:20])[CH2:15][CH2:16][CH2:17][CH2:18]1.[CH2:21]([c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1)[N:28]([CH:29]([CH:30]=[O:31])[CH2:32][c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1)[CH2:39][c:40]1[cH:41][cH:42][cH:43][cH:44][cH:45]1.[CH3:46][CH2:47][O:48][CH2:49][CH3:50].[CH:1]([Li:2])([CH2:3][CH3:4])[CH3:5]>>[C:6]([CH3:7])([CH3:8])([CH3:9])[O:10][C:11](=[O:12])[N:13]1[CH:14]([CH2:19][CH3:20])[CH2:15][CH2:16][CH2:17][CH:18]1[CH:30]([CH:29]([N:28]([CH2:21][c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1)[CH2:39][c:40]1[cH:41][cH:42][cH:43][cH:44][cH:45]1)[CH2:32][c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1)[OH:31]

Participants

5

Reactant 4

HCID 3283Diethyl EtherHCID 5638962-(Dibenzylamino)-3-phenylpropanalHCID 12170201tert-Butyl 2-Ethylpiperidine-1-carboxylateHCID 178418400CID 53628100

Product 1

HCID 77589796Tert-butyl 2-[2-(dibenzylamino)-1-hydroxy-3-phenylpropyl]-6-ethylpiperidine-1-carboxylate

Sources & evidence

ORD record
ord-66d7f66970434cac93a38a8e40324010
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Linked notes

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