N2-[(1,1-dimethylethoxy)carbonyl]-L-lysine (HCID 100148)

名称と識別子

優先名称: N2-[(1,1-dimethylethoxy)carbonyl]-L-lysine
IUPAC: 6-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid
現地名: Nα-(tert-ブトキシカルボニル)-L-リジン
英語名: Boc-Lys-OH
分子式: C11H22N2O4
分子量: 246.3

名称と別名

EINECS 237-303-4NSC 343721N2-((1,1-Dimethylethoxy)carbonyl)-L-lysineN2-[(1,1-DIMETHYLETHOXY)CARBONYL]-L-LYSINERefChem:831503237-303-46-amino-2-{[(tert-butoxy)carbonyl]amino}hexanoic acid186706-75-2Na-Boc-L-lysineN-alpha-Boc-L-lysineN-(Tert-Butoxycarbonyl)-L-LysineNa-Boc-D-lysine

名称をさらに表示

Nα-(tert-ブトキシカルボニル)-L-リジンNα-(tert-ブトキシカルボニル)-L-リシンBoc-リシンN2-(tert-ブトキシカルボニル)リシンNα-(tert-ブチルオキシカルボニル)-L-リシンN2-[(1,1-ジメチルエトキシ)カルボニル]-L-リシンN2-(tert-ブチルオキシカルボニル)-L-リシン(S)-2-[(tert-ブチルオキシカルボニル)アミノ]-6-アミノヘキサン酸N2-(tert-ブトキシカルボニル)-L-リシンBOC-LYS-OHNα-Boc-L-リジンBOC‐LYS‐OHNΑ‐BOC‐L‐リシンN-BOC-L-リシンN(ALPHA)-BOC-L-リシンNΑ-BOC-L-リシン(2S)-6-アミノ-2-{[(tert-ブトキシ)カルボニル]アミノ}ヘキサン酸BOC-LYSBOC-LYS-OHBOC-L-LYSINEBOC-LYSINEBOC-L-LYS-OHN-ALPHA-T-BOC-L-LYSINENα-(tert-Butoxycarbonyl)-L-lysineBoc-Lys-OH 99%Boc-Lys-OH,97%

NSC343721n-epsilon-boc-l-lysineSCHEMBL376450(2R)-6-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acidDQUHYEDEGRNAFO-UHFFFAOYSA-NDTXSID2013835526-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acidSTR06753

データベース識別子

CAS: 13734-28-6、186706-75-2
PubChem CID: 100148
DTXSID: DTXSID201383552
EC Number: 237-303-4
Nikkaji: J1.775.904C

物性

構造計算による物性

XLogP: -1.6
極性表面積: 102 Å²
水素結合供与体数: 3
水素結合受容体数: 5
回転可能結合数: 8
重原子数: 17
形式電荷: 0
複雑度: 261

物理化学的性質

融点: 205 °C · ~205 °C (dec.)(lit.)
比旋光度: 22 · 22 º (c=2, CH3OH)
沸点: 389.3 °C · 389.3°C (rough estimate)
比重(密度): 1.1313 · 1.1313 (rough estimate)
屈折率: 21.5 ° · 21.5 ° (C=2, MeOH)
貯蔵温度: Keep in dark place,Sealed in dry,Room Temperature
溶解性: 酢酸（微量）、メタノール（微量、超音波処理）、水（微量、加熱、
酸解離定数(Pka): 3.92 · 3.92±0.21(Predicted)
外見: 粉
色: 白い
水溶解度: 水に溶ける。メタノールにわずかに溶ける。
BRN: 4252546 · 4252546
主な用途: ペプチド合成
InChI: InChI=1S/C11H22N2O4/c1-11(2,3)17-10(16)13-8(9(14)15)6-4-5-7-12/h8H,4-7,12H2,1-3H3,(H,13,16)(H,14,15)/t8-/m0/s1
InChIKey: DQUHYEDEGRNAFO-QMMMGPOBSA-N
SMILES: C(O)(=O)[C@H](CCCCN)NC(OC(C)(C)C)=O
CAS データベース: 13734 · 13734-28-6(CAS DataBase Reference)

化学的性質

化学的特性white to off-white powder

安全と法規制

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 50% (2 of 4) of reports.

Warning

H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (50%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (50%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 4 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 2 of 4 reports by companies.；There are 2 notifications provided by 2 of 4 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Hazard Classes and CategoriesSkin Irrit. 2 (50%)；Eye Irrit. 2A (50%)；STOT SE 3 (50%)

安全データ

wgk: 3
hs_code: 2924 19 00
risk_code: 20/21/22-36/37/38
hazard_code: Xn
safety_code: 24/25-36-26
hazard_class: IRRITANT
ストレージクラス: 11 - Combustible Solids

化学と産業

上流・下流製品情報

上流原料

水和物アセトントリエチルアミン二炭酸ジ-tert-ブチル L-(+)-リジン

下流製品

BOC-LYS(FMOC)-OH N6-(2-アジドエトキシカルボニル)-L-リシン L-(-)-N-Α-BOC-アミノ-Ε-カプロラクタム N6-{[(2-Phenylethyl)amino]carbonothioyl}lysine (PEITC-Lys)N-α-Boc-propargyl-lysine-OH H-Lys(ivdde)-OH

サプライヤー50 社

北京华美互利生物化工010-56205725 · [email protected]

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奥思恩（北京）科技有限公司18201687790 18201687790 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

Nα-(tert-ブトキシカルボニル)-L-リジン

基本情報