データを補完しています。通常は 1 分以内に完了します
基本情報
- CAS
1308-04-9- 標準SMILES
[Co+3].[Co+3].[O-2].[O-2].[O-2]- InChIKey
KAGOZRSGIYZEKW-UHFFFAOYSA-N- 分子式
- Co2O3
- 平均分子量
- 165.865 g/mol
- 単同位体質量
- 165.85113386
概要
Cobalt(III) oxide is an inorganic compound with the formula Co2O3 and is an oxide of cobalt. It is used as a catalyst. Cobalt is a metallic element with the atomic number 27. It is found naturally in rocks, soil, water, plants, and animals. In small amounts cobalt is an essential element for life, as it is part of vitamin B12. However, excess exposure is known to exhibit toxic effects. (L29, L30, L493)
名称と識別子
- 優先名称
- Cobalt oxide (Co2O3)
- IUPAC
- bis(cobalt(3+));tris(oxygen(2-))
名称と別名
データベース識別子
- CAS
1308-04-9- PubChem CID
- 10176285
- DTXSID
DTXSID20893870
物性
構造計算による物性補完中
- 極性表面積
- 3 Ų
- 水素結合供与体数
- 0
- 水素結合受容体数
- 3
- 回転可能結合数
- 0
- 重原子数
- 5
- 形式電荷
- 0
- 複雑度
- 0
実験および物理化学的性質
安全と法規制
危険有害性情報
安全と保護具
First Aid Measures
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Refer for medical attention .
Spillage Disposal
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
毒性情報
Exposure Routes
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.
Inhalation (L29) ; oral (L29) ; dermal (L29)
Toxicity Summary
Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, causing increased lipid peroxidation, DNA damage, and inducing certain enzymes that lead to cell apoptosis. Cobalt has also been shown to block inorganic calcium channels, possibly impairing neurotransmission. Cobalt can also chelate lipoic acids, impairing oxidation of pyruvate or fatty acids. In addition, cobalt may inhibit DNA repair by interacting with zinc finger DNA repair proteins, and has also been shown to inhibit heme synthesis and glucose metabolism. Cobalt may activate specific helper T-lymphocyte cells and interact directly with immunologic proteins, such as antibodies (IgA and IgE) or Fc receptors, resulting in immunosensitization. (L29)
Signs and Symptoms
Cough. Sore throat. Shortness of breath. Wheezing.
Redness. Pain.
Abdominal pain. Nausea.
Cobalt inhalation can cause asthma-like breathing problems. Skin contact is known to result in contact dermatitis, which is characterized by irritation and rashes. Ingesting large amounts of cobalt may cause nausea and vomiting. (L2090)
化学と産業
薬理情報
Metabolism/Metabolites
Cobalt is absorbed though the lungs, gastrointestinal tract, and skin. Since it is a component of the vitamin B12 (cyanocobalamin), it is distributed to most tissues of the body. It is transported in the blood, often bound to albumin, with the highest levels being found in the liver and kidney. Cobalt is excreted mainly in the urine and faeces. (L29)
用途と製造
サプライヤー100 社
関連反応
現在のフィルター条件では反応記録がありません。
化合物ノート
読み込み中…