8059-24-3Cc1ncc(COP(=O)([O-])[O-])c(C)c1ORBCOYOYDYNXAFA-UHFFFAOYSA-LVitamin B6 is a group of water-soluble vitamins essential for metabolism and normal physiological functions. B6 vitamins, including pyridoxine, pyridoxal, and pyridoxamine, are converted in vivo to pyridoxal phosphate, a cofactor necessary for the synthesis of amino acids, neurotransmitters, and sphingolipids. More than 100 enzymes involved in protein metabolism require vitamin B6 as a cofactor. Vitamin B6 is essential to red blood cell, nervous system, and immune systems functions and helps maintain normal blood glucose levels. Vitamin B6 is found in a wide variety of foods including cereals, beans, meat, poultry, fish, and some fruits and vegetables. (NCI04)
8059-24-3安全情報は参考情報です。供給元の安全データシート(SDS)、適用法令、専門家による評価に代わるものではありません。
Chemical: Vitamin B6
Regulation (EC) No 1831/2003 (amended)
Vitamin B6: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
VITAMIN B 6 refers to several PICOLINES (especially PYRIDOXINE; PYRIDOXAL; & PYRIDOXAMINE) that are efficiently converted by the body to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, and aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into PYRIDOXAMINE phosphate. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990). Most of vitamin B6 is eventually degraded to PYRIDOXIC ACID and excreted in the urine. [ChemIDplus] Pyridoxine hydrochloride (a form of vitamin B6) is used as a nutritional additive in animal feeds and considered safe for all species; [ExPub: EFSA - FEEDAP]
Farming (Feed Additives) [Category: Industry]
解説ビタミンB6,ビタミンビーろく,ピリドキシン,ピリドキサル,ピリドキサミンが含まれる。ピリドキシンは水溶性で蛋白質代謝に関連が深く,これが欠乏すると,蛋白質から炭水化物,脂肪への転換が押えられる。米ぬか,胚芽,酵母,肝臓に多く含まれる。ビタミン B6 欠乏症では,ペラグラ様皮膚炎,脂漏性皮膚炎,食欲不振,吐き気,口唇炎,B6 反応性鉄芽球性貧血などが起る。1日 10~50mgを内服または注射すると,症状は消失する。水溶性ビタミンのひとつ。たんぱく質の代謝に不可欠な補酵素。皮膚炎を予防する物質として発見されたビタミン。魚類、肉類、鶏卵、豆類などに多く含まれる。大脳や神経の刺激伝達物質を生成し、脳機能を維持する働きをもつほか、赤血球中のヘム合成に関わり血液をサラサラに維持、皮膚や粘膜の抵抗力の向上、免疫力強化、貧血症の予防・改善、動脈硬化症の予防などさまざまな作用をもつ。
説明Vitamin B6 (vitB6), or pyridoxine, is an important compound for general cellular metabolism. Since its discovery in 1934 by Gyrgy and colleagues, it has been implicated as a co-factor in more than 140 biochemical reactions in the cell. Although most vitB6 co-catalyzed reactions are related to amino acid biosynthesis and catabolism, vitB6 also contributes to fatty acid biosynthesis, breakdown of certain storage compounds in animals and plants, as well as in the biosynthesis of plant hormones, neurotransmitters, and organelle-specific compounds such as chlorophyll. In addition, vitamin B6 can quench reactive oxygen species (ROS). Because of its role in ROS scavenging and chlorophyll synthesis, vitamin B6 benefits photosynthesis and is discussed as a possible factor in alleviating abiotic and biotic stress. Vitamin B6 (pyridoxal 5′-phosphate) participates in the process of synthesizing dopamine, epinephrine, norepinephrine, serotonin and GABA. It has also been found to be an antioxidant.
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使用Vitamin B6 comprises a group of six water-soluble compounds, including pyridoxal, pyridoxamine, pyridoxine, and their 5′-phosphates. It functions as a versatile coenzyme participating in over 100 biochemical reactions and is generally considered to have negligible toxicity due to its ready metabolism and excretion[1][2][3]. Vitamin B6 serves as a cofactor for approximately 160 reactions, including glycogen breakdown, amino acid transformations, and the synthesis of neurotransmitters such as GABA, dopamine, norepinephrine, and serotonin. Therapeutic administration is used to treat vitamin B6 deficiency (typically around 50 mg/day orally), prevent peripheral neuropathy induced by isoniazid, and manage nausea and vomiting during pregnancy[1][2][3][4].
定義本品は、ビタミンB6であり、次の化学式で表される。