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2-[2-(4-Fluorophenyl)-2-oxo-1-phenyl-ethyl]-4-methyl-3-oxo-pentanoic Acid, (4-Benzyloxy-phenyl)-amide
4-Methyl-3-oxo-N-(4-benzyloxyphenyl)-2-[1-phenyl-2-(4-fluorophenyl)-2-oxoethyl]pentaMide · 4-Fluoro-α-(2-Methyl-1-oxopropyl)-γ-oxo-β-phenyl-N-[4-(phenylMethoxy)phenyl]benzenebutanaMide · Benzenebutanamide, 4-fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-β-phenyl-N-[4-(phenylmethoxy)phenyl]- · 2-[2-(4-Fluorophenyl)-2-oxo-1-phenyl-ethyl]-4-methyl-3-oxo-pentanoic Acid, (4-Benzyloxy-phenyl)-amide
![2-[2-(4-Fluorophenyl)-2-oxo-1-phenyl-ethyl]-4-methyl-3-oxo-pentanoic Acid, (4-Benzyloxy-phenyl)-amide の分子構造式](/img/chemical/10697370.png)
識別子と物理属性
| CAS No. | 163217-67-2 |
|---|---|
| 分子式 | C33H30FNO4 |
| 平均分子量 | 523.6 g/mol |
| 単同位体質量 | 523.2158866 g/mol |
| SMILES | CC(C)C(=O)C(C(=O)Nc1ccc(OCc2ccccc2)cc1)C(C(=O)c1ccc(F)cc1)c1ccccc1 |
| InChIKey | GQGGAQUHBXLZMT-UHFFFAOYSA-N |
| PubChem CID | 10697370 |
| DTXSID | DTXSID90443609 |
化学・物理的性質
| XLogP | 7.2 |
|---|---|
| 極性表面積 | 72.5 |
| 水素結合供与体数 | 1 |
| 水素結合受容体数 | 5 |
| 回転可能結合数 | 11 |
| 重原子数 | 39 |
| 形式電荷 | 0 |
| 複雑度 | 788 |
| 溶解度 | soluble in Acetone, Chloroform, Dichloromethane, Ethyl Acetate |
| 外観・状態 | Solid |
| 色 | Off-White |
化学的特性
Off-White Solid
用途
使用
A intermediate of the metabolite of Atorvastin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.