CAS 527-62-8 2-Amino-4,6-dichlorophenol (HCID 10699)

概要

Long needles (from carbon disulfide). Sublimes (at 0.06 mmHg) at 158-176 °F. (NTP, 1992)

名称と識別子

優先名称: 2-Amino-4,6-dichlorophenol
IUPAC: 2-amino-4,6-dichlorophenol
現地名: 2,4-ジクロロ-6-アミノフェノール
英語名: 2-Amino-4,6-dichlorophenol
分子式: C6H5Cl2NO
分子量: 178.02

名称と別名

2-AMINO-4,6-DICHLOROPHENOL527-62-82,4-Dichloro-6-aminophenolES86DYT9KHNSC-6584644,6-DICHLORO-O-AMINOPHENOLDTXSID008705834,6-DICHLORO-2-AMINOPHENOLRefChem:464010DTXCID20204361208-421-3Phenol, 2-amino-4,6-dichloro-

名称をさらに表示

2-アミノ-4,6-ジクロロフェノール4,6-ジクロロ-o-アミノフェノール2,4-ジクロロ-6-アミノフェノール2-アミノ-4,6-ジクロロフェノール塩化物3,5-ジクロロ-2-ヒドロキシアニリン2,4-Dichloro-6-amino2-Amino-4,6-chlorophenol4,6-Dichloro-α-aminophenol2-amino-4,6-dichloro-pheno6-AMINO-2,4-DICHLORO PHENOL

2-Amino-4,6-dichloro-phenolMFCD00035766CCRIS 76853,5-Dichloro-2-hydroxyanilineUNII-ES86DYT9KHEINECS 208-421-36-amino-2,4-dichlorophenolNSC658464

データベース識別子

CAS: 527-62-8
PubChem CID: 10699
DTXSID: DTXSID00870583
UNII: ES86DYT9KH
EC Number: 208-421-3
Nikkaji: J7.742I

物性

構造計算による物性

XLogP: 2.3
極性表面積: 46.3 Å²
水素結合供与体数: 2
水素結合受容体数: 2
回転可能結合数: 0
重原子数: 10
形式電荷: 0
複雑度: 122

実験および物理化学的性質

Melting Point203 to 205 °F (decomposes) (NTP, 1992)

Physical DescriptionLong needles (from carbon disulfide). Sublimes (at 0.06 mmHg) at 158-176 °F. (NTP, 1992)

物理化学的性質

融点: 97 °C · 97 °C
沸点: 286.5 · 286.5±40.0 °C(Predicted)
比重(密度): 1.2549 · 1.2549 (rough estimate)
屈折率: 1.568 · 1.5680 (estimate)
貯蔵温度: Keep in dark place,Sealed in dry,Room Temperature
酸解離定数(Pka): 7.85 · 7.85±0.23(Predicted)
外見: 個体
色: 黄色から茶色
Merck: 14 · 14,437
CAS データベース: 527 · 527-62-8(CAS DataBase Reference)
EPAの化学物質情報: 2 · 2-Amino-4,6-dichlorophenol (527-62-8)

化学的性質

化学的特性Off-white or light brown crystals

安全と法規制

GHS分類

GHS Classification · 4 件

Danger

H301 (66.7%): Toxic if swallowed [Danger Acute toxicity, oral]

P261, P262, P264, P264+P265, P270, P271, P280, P301+P316, P301+P317, P302+P352, P304+P340, P305+P351+P338, P316, P317, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 3 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危険有害性情報

DOT LabelPoison

Fire HazardsFlash point data for this chemical are not available. It is probably combustible. (NTP, 1992)

Health HazardsSYMPTOMS: Symptoms of exposure to this compound may include irritation of the skin, eyes and mucous membranes.

Reactive GroupPhenols and Cresols

Reactivity Profile2-AMINO-4,6-DICHLOROPHENOL may react with strong oxidizers and mineral acids or bases (NTP, 1992).

Air and Water ReactionsMay be sensitive to prolonged exposure to air/or light.

安全と保護具

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)

First Aid · 1 件

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 件

SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then dampen the solid spill material with toluene, then transfer the dampened material to a suitable container. Use absorbent paper dampened with toluene to pick up any remaining material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent-wash all contaminated surfaces with toluene followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Isolation and EvacuationExcerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:

Personal Protective Equipment (PPE) · 1 件

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

安全データ

hs_code: 2922290090
化審法: (3)-990
hazard_note: Irritant
hazard_class: 6.1

化学と産業

応用分野

一般的な説明Long needles (from carbon disulfide). Sublimes (at 0.06 mm Hg) at 158-176°F.

調製方法

純化方法Crystallise the phenol from CS2 or *benzene. It sublimes at 0.06mm. The hydrochloride has m 280-285o from EtOH. [Meyer Helv Chim Acta 41 1890 1958, Beilstein 13 II 185, 13 III 856, 13 IV 889.]