基本情報
- CAS
3589-21-7- 標準SMILES
CC(CN(C)C)CN1c2ccccc2CCc2ccccc21.Cl- InChIKey
ZAEWBFAYJAWHJG-UHFFFAOYSA-N- 分子式
- C20H27ClN2
- 平均分子量
- 330.9 g/mol
- 単同位体質量
- 330.1862766
名称と識別子
- 優先名称
- Trimipramine hydrochloride
- IUPAC
- 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N,2-trimethylpropan-1-amine;hydrochloride
名称と別名
Trimipramine hydrochlorideTrimeprimine hydrochloride3589-21-792NQ305AFLNSC-169472Trimipramine Monohydrochloride5H-Dibenz(b,f)azepine, 5-(3-(dimethylamino)-2-methylpropyl)-10,11-dihydro-, monohydrochloride5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl-, monohydrochlorideRefChem:203372Sapilent hydrochlorideTrimepramine hydrochlorideTrimepramine
名称をさらに表示
Trimipramine HClTrimeprimine-hydrochlorideTrimiprimine hydrochlorideTrimipromine hydrochlorideTrimepropimine hydrochlorideNSC 169472Trimeproprimine hydrochlorideUNII-92NQ305AFL
データベース識別子
- CAS
3589-21-7- PubChem CID
- 107128
- DTXSID
DTXSID001350442- UNII
- 92NQ305AFL
物性
構造計算による物性
- 極性表面積
- 6.5 Ų
- 水素結合供与体数
- 1
- 水素結合受容体数
- 2
- 回転可能結合数
- 4
- 重原子数
- 23
- 形式電荷
- 0
- 複雑度
- 317
化学と産業
薬理情報
MeSH Pharmacological Classification
Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However, the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.
Drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants (ANTIDEPRESSIVE AGENTS, TRICYCLIC) and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
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