N-(2-(Dimethylamino)ethyl)acridine-4-carboxamide

HCID 107805

基本情報

CAS: 89459-25-6
標準SMILES: CN(C)CCNC(=O)c1cccc2cc3ccccc3nc12
InChIKey: XBGNERSKEKDZDS-UHFFFAOYSA-N
分子式: C18H19N3O
平均分子量: 293.4 g/mol
単同位体質量: 293.15281223

概要

Acridine Carboxamide has been used in trials studying the treatment of Lung Cancer and Brain and Central Nervous System Tumors.

名称と識別子

優先名称: N-(2-(Dimethylamino)ethyl)acridine-4-carboxamide
IUPAC: N-[2-(dimethylamino)ethyl]acridine-4-carboxamide

名称と別名

Daca89459-25-6Acridine carboxamideN-[2-(dimethylamino)ethyl]acridine-4-carboxamideDACA-NN-(2-(dimethylamino)ethyl)acridine-4-carboxamideNSC-601316NSC 601316N-(2'-(dimethylamino)ethyl)acridine-4-carboxamideSN 229954-Acridinecarboxamide, N-(2-(dimethylamino)ethyl)-4-Acridinecarboxamide, N-[2-(dimethylamino)ethyl]-

名称をさらに表示

DTXSID602377390N3V8R4E13RefChem:109390DTXCID60160230N-(2-(Dimehtylamino)ethyl)acridine-4-carboxamideXR-5000N-(2-(Dimethylamino)ethyl)-4-acridinecarboxamideN-[2-(dimethylamino)ethyl]-4-acridinecarboxamide

データベース識別子

CAS: 89459-25-6
PubChem CID: 107805
DTXSID: DTXSID60237739
ChEMBL: CHEMBL9940
UNII: 0N3V8R4E13
Nikkaji: J330.650J

物性

構造計算による物性

XLogP: 3.3
極性表面積: 45.2 Å²
水素結合供与体数: 1
水素結合受容体数: 3
回転可能結合数: 4
重原子数: 22
形式電荷: 0
複雑度: 385

実験および物理化学的性質

DrugsPharmaceuticals -> Listed in ZINC15

化学と産業

薬理情報

MeSH Pharmacological Classification · 1 件

Compounds that inhibit the activity of DNA TOPOISOMERASE II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic form of topoisomerase II and ANTIBACTERIAL AGENTS which target the prokaryotic form of topoisomerase II.

化合物ノート

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