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SOL IN ACETONE

MISCIBLE IN ETHYL ALCOHOL, ETHYL ETHER

-35 °F (NFPA, 2010)

-35 °F (closed cup)

Danger

H220: Extremely flammable gas [Danger Flammable gases]

P203, P210, P222, P280, P377, P381, and P403 (click each P-code to see the statement)

Danger

H220 (100%): Extremely flammable gas [Danger Flammable gases]

P203, P210, P222, P280, P377, P381, P403, and P410+P403 (click each P-code to see the statement)

Excerpt from ERG Guide 115 [Gases - Flammable (Including Refrigerated Liquids)]:

· EXTREMELY FLAMMABLE.

· EXTREMELY FLAMMABLE.

HIGHLY FLAMMABLE; DANGEROUS FIRE ... RISK.

FLAMMABLE LIMITS: LOWER 2%; UPPER 10.1%.

Excerpt from ERG Guide 115 [Gases - Flammable (Including Refrigerated Liquids)]:

· Vapors may cause dizziness or asphyxiation without warning, especially when in closed or confined areas.

· Vapors may cause dizziness or asphyxiation without warning, especially when in closed or confined areas.

Risk of fire and explosion; [Hawley] Extremely flammable; Forms spontaneously combustible peroxides on contact with air; Evaporating liquid can cause frostbite; [CAMEO] Acts as general anesthetic in inhalation animal experiments; [RTECS] Can form explosive mixtures with air; Inhalation can cause CNS depression and asphyxiation; [MSDSonline]

1039 115

1039 115

Ethers, such as ETHYL METHYL ETHER, can act as bases. They form salts with strong acids and addition complexes with Lewis acids. The complex between diethyl ether and boron trifluoride is an example. Ethers may react violently with strong oxidizing agents. In other reactions, which typically involve the breaking of the carbon-oxygen bond, ethers are relatively inert.

/GUIDE 115: GASES - FLAMMABLE (Including Refrigerated Liquids)/ Fire or Explosion: EXTREMELY FLAMMABLE. Will be easily ignited by heat, sparks or flames. Will form explosive mixtures with air. Vapors from liquefied gas are initially heavier than air and spread along ground. CAUTION: Hydrogen (UN1049), Deuterium (UN1957), Hydrogen, refrigerated liquid (UN1966) and Methane (UN1971) are lighter than air and will rise. Hydrogen and Deuterium fires are difficult to detect since they burn with an invisible flame. Use an alternate method of detection (thermal camera, broom handle, etc.) Vapors may travel to source of ignition and flash back. Cylinders exposed to fire may vent and release flammable gas through pressure relief devices. Containers may explode when heated. Ruptured cylinders may rocket.

/GUIDE 115: GASES - FLAMMABLE (Including Refrigerated Liquids)/ Health: Vapors may cause dizziness or asphyxiation without warning. Some may be irritating if inhaled at high concentrations. Contact with gas or liquefied gas may cause burns, severe injury and/or frostbite. Fire may produce irritating and/or toxic gases.

/GUIDE 115: GASES - FLAMMABLE (Including Refrigerated Liquids)/ Public Safety: CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number listed on the inside back cover. As an immediate precautionary measure, isolate spill or leak area for at least 100 meters (330 feet) in all directions. Keep unauthorized personnel away. Stay upwind. Many gases are heavier than air and will spread along ground and collect in low or confined areas (sewers, basements, tanks). Keep out of low areas.

/GUIDE 115: GASES - FLAMMABLE (Including Refrigerated Liquids)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Structural firefighters' protective clothing will only provide limited protection. Always wear thermal protective clothing when handling refrigerated/cryogenic liquids.

For more DOT Emergency Guidelines (Complete) data for ETHYL METHYL ETHER (8 total), please visit the HSDB record page.

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.

Excerpt from ERG Guide 115 [Gases - Flammable (Including Refrigerated Liquids)]:

General First Aid:

General First Aid:

· Wear positive pressure self-contained breathing apparatus (SCBA).

· Wear positive pressure self-contained breathing apparatus (SCBA).

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

This compound should be susceptible to removal from waste water by air stripping. /Bis(2-chloroethyl)ether/

Excerpt from ERG Guide 115 [Gases - Flammable (Including Refrigerated Liquids)]:

Immediate precautionary measure

Immediate precautionary measure

Excerpt from ERG Guide 115 [Gases - Flammable (Including Refrigerated Liquids)]:

Wear full protective clothing & positive pressure self-contained breathing apparatus.

· DO NOT EXTINGUISH A LEAKING GAS FIRE UNLESS LEAK CAN BE STOPPED.

· DO NOT EXTINGUISH A LEAKING GAS FIRE UNLESS LEAK CAN BE STOPPED.

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 48(SRC), determined from an estimated log Kow of 0.56(2,SRC) and a regression-derived equation(3), indicates that ethyl methyl ether is expected to have very high mobility in soil(SRC). Volatilization of ethyl methyl ether from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 6.7X10-4 atm-cu m/mole(SRC), using a fragment constant estimation method(4). Volatilization of ethyl methyl ether from dry soil surfaces is expected(SRC) based upon a vapor pressure of 1493 mm Hg at 25 °C(5). Limited data are present in the scientific literature regarding the biodegradation of ethyl methyl ether, but a theoretical BOD of 0 to 1.1% over a period of 5 days and 0 to 1% over a period of 4 weeks for diethyl ether and dimethyl ether(6,7), respectively, suggests biodegradation may be slow(SRC).

AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 48(SRC), determined from an estimated log Kow of 0.56(2,SRC) and a regression-derived equation(3), indicates that ethyl methyl ether is not expected to adsorb to suspended solids and sediment in water(SRC). Ethyl methyl ether is expected to volatilize from water surfaces(3,SRC) based on an estimated Henry's Law constant of 6.7X10-4 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). Estimated volatilization half-lives for a model river and model lake are 3.3 hours and 3.4 days, respectively(3,SRC). According to a classification scheme(5), an estimated BCF of 1.6(3,SRC), from an estimated log Kow(2,SRC), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Limited data are present in the scientific literature regarding the biodegradation of ethyl methyl ether, but theoretical BODs of 0 to 1.1% over a period of 5 days and 0 to 1% over a period of 4 weeks for the structurally similar diethyl ether and dimethyl ether(6,7), respectively, suggests biodegradation may be slow(SRC).

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), ethyl methyl ether, which has a vapor pressure of 1493 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase ethyl methyl ether is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 2.3 days(3,SRC). Direct photolysis is not expected to be an important removal process since aliphatic ethers do not absorb light in the environmental spectrum(4).

The Koc of ethyl methyl ether is estimated as approximately 48(SRC), using an estimated log Kow of 0.56(1,SRC) and a regression-derived equation(2,SRC). According to a classification scheme(3), this estimated Koc value suggests that ethyl methyl ether is expected to have very high mobility in soil(SRC).

An estimated BCF of 1.6 was calculated for ethyl methyl ether(SRC), using an estimated log Kow of 0.56(1,SRC) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low.

The Henry's Law constant for ethyl methyl ether is estimated as 6.7X10-4 atm-cu m/mole(SRC) using a fragment constant estimation method(1). This Henry's Law constant indicates that ethyl methyl ether is expected to volatilize from water surfaces(2,SRC). Based on this Henry's Law constant, the estimated volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec) is approximately 3.3 hours(2,SRC). The estimated volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec) is approximately 3.4 days(2,SRC). Ethyl methyl ether's Henry's Law constant(1,SRC) indicates that volatilization from moist soil surfaces may occur(SRC). Volatilization of ethyl methyl ether from dry soil surfaces is expected(SRC)

The rate constant for the vapor-phase reaction of ethyl methyl ether with photochemically-produced hydroxyl radicals has been estimated as 7.0X10-12 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1,SRC). This corresponds to an atmospheric half-life of about 2.3 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1,SRC). Direct photolysis is not expected to be an important removal process since aliphatic ethers do not absorb light in the environmental spectrum(2). Ethyl methyl ether is not expected to undergo hydrolysis in the environment due to the lack of hydrolyzable functional groups(3).

NIOSH (NOES Survey 1981-1983) has statistically estimated that 10 workers are potentially exposed to ethyl methyl ether in the US(1). Occupational exposure to ethyl methyl ether may occur through inhalation and dermal contact with this compound at workplaces where ethyl methyl ether is used(SRC).

If released to air, a vapor pressure of 1493 mm Hg at 25 °C indicates ethyl methyl ether will exist solely as a vapor in the ambient atmosphere. Vapor-phase ethyl methyl ether will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 2.3 days. Direct photolysis is not expected to be an important removal process since aliphatic ethers do not absorb light in the environmental spectrum. If released to soil, ethyl methyl ether is expected to have very high mobility based upon an estimated Koc of 48. Volatilization from moist soil surfaces is expected to be an important fate process based upon an estimated Henry's Law constant of 6.7X10-4 atm-cu m/mole. Ethyl methyl ether is expected to volatilize from dry soil surfaces based upon its vapor pressure. Limited data are present in the scientific literature regarding the biodegradation of ethyl methyl ether; however, ethers are generally resistant to biodegradation. 0 to 1.1% theoretical BOD was observed over a period of 5 days for diethyl ether and 0 to 1% theoretical BOD was observed over a period of 4 weeks for dimethyl ether, structural analogues of ethyl methyl ether. If released into water, ethyl methyl ether is not expected to adsorb to suspended solids and sediment in water based upon the estimated Koc. Volatilization from water surfaces is expected to be an important fate process based upon this compound's estimated Henry's Law constant. Estimated volatilization half-lives from a model river and model lake are 3.4 hours and 3.4 days, respectively. An estimated BCF of 1.6 suggests the potential for bioconcentration in aquatic organisms is low. Hydrolysis is not expected to be an important process due to the lack of hydrolyzable functional groups. Occupational exposure to ethyl methyl ether may occur through inhalation and dermal contact with this compound at workplaces where ethyl methyl ether is used. (SRC)

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Provide a low-stimulus environment. Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Treat frostbite by rapid rewarming ... . /Ethers and related compounds/

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious or in respiratory arrest. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with D5W TKO /SRP: To keep open, "minimal flow rate"/. Use lactated Ringer's if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors for hypotension with a normal fluid volume. Watch for signs of fluid overload ... . Treat seizures with diazepam ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Ethers and related compounds/