基本情報
- 標準SMILES
CC(=O)[O-].CC(=O)[O-].[Ba+2]- InChIKey
ITHZDDVSAWDQPZ-UHFFFAOYSA-L- 分子式
- C4H6BaO4
- 平均分子量
- 255.41 g/mol
- 単同位体質量
- 255.93185587
概要
Barium acetate is an acetate salt in which the cationic component is barium(2+). It has a role as a catalyst and a mordant. It is an organic barium salt and an acetate salt.
名称と識別子
- 優先名称
- Barium acetate
- IUPAC
- barium(2+) diacetate
名称と別名
名称をさらに表示
データベース識別子
- CAS
543-80-6- PubChem CID
- 10980
- DTXSID
DTXSID7020130- ChEBI
CHEBI:190441- UNII
- FBA31YJ60R
- EC Number
- 208-849-0
- Nikkaji
- J422G
物性
構造計算による物性
- 極性表面積
- 80.3 Ų
- 水素結合供与体数
- 0
- 水素結合受容体数
- 4
- 回転可能結合数
- 0
- 重原子数
- 9
- 形式電荷
- 0
- 複雑度
- 25.5
実験および物理化学的性質
Density
2.47 g/cm³
2.468 @25 °C
Physical Description
Dry Powder
White solid; [Hawley] White crystals, soluble in water; [MSDSonline]
WHITE CRYSTALS OR POWDER.
安全と法規制
GHS分類
GHS Classification
This chemical does not meet GHS hazard criteria for 0.3% (1 of 287) of reports.
Warning
H302 (99.7%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P270, P271, P301+P317, P304+P340, P317, P330, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 287 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Danger
危険有害性情報
Regulatory Information
Chemical: Acetic acid, barium salt
Acetic acid, barium salt (2:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Acetic acid, barium salt (2:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Status: Active Update: 16-06-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/24153
Barium acetate: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and Categories
Acute Tox. 4 (99.7%)
Acute toxicity (Oral) - Category 4
Acute toxicity (Oral) - Category 4
安全と保護具
First Aid Measures
Fresh air, rest.
Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Refer for medical attention .
Spillage Disposal
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
毒性情報
Health Effects
The health effects of the different barium compounds depend on how well the compound dissolves in water or the stomach contents. At low doses, barium acts as a muscle stimulant, while higher doses affect the nervous system, causing cardiac irregularities, tremors, weakness, anxiety, dyspnea, paralysisand possibly death. Barium may also cause gastrointestinal disturbances, damage the kidneys and cause decreases in body weight. (L214)
Exposure Routes
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.
Oral (L214) ; inhalation (L214)
Toxicity Summary
Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to intracellular compartments. The intracellular translocation of potassium results in a decreased resting membrane potential, making the muscle fibers electrically unexcitable and causing paralysis. Some of these barium's effects may also be due to barium induced neuromuscular blockade and membrane depolarization. (L214)
Signs and Symptoms
Abdominal pain. Diarrhoea. Nausea. Vomiting. Weakness. Shortness of breath.
Ingesting excess barium may cause vomiting, abdominal cramps, diarrhea, difficulties in breathing, increased or decreased blood pressure, numbness around the face, and muscle weakness. High levels may result in changes in heart rhythm or paralysis and possibly death. (L214)
化学と産業
薬理情報
Metabolism/Metabolites
Barium compounds are absorbed via ingestion and inhalation, the extent of which depends on the individual compound. In the body, the majority of the barium is found in the bone, while small amounts exists in the muscle, adipose, skin, and connective tissue. Barium is not metabolized in the body, but it may be transported or incorporated into complexes or tissues. Barium is excreted in the urine and faeces. (L214)
用途と製造
Uses
Used as a chemical reagent; to make other acetates; as a textile mordant; in paint and varnish driers; [Hawley] Used as a lubricant and catalyst; [Merck Index]
Painting (Pigments, Binders, and Biocides) [Category: Paint]
Use (kg; approx.) in Germany (2009): >75000
General Manufacturing Information
Not Known or Reasonably Ascertainable
Acetic acid, barium salt (2:1): ACTIVE
関連反応
関連ノート
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