Barium acetate

HCID 10980CAS 543-80-6

基本情報

標準SMILES
CC(=O)[O-].CC(=O)[O-].[Ba+2]
InChIKey
ITHZDDVSAWDQPZ-UHFFFAOYSA-L
分子式
C4H6BaO4
平均分子量
255.41 g/mol
単同位体質量
255.93185587

概要

Barium acetate is an acetate salt in which the cationic component is barium(2+). It has a role as a catalyst and a mordant. It is an organic barium salt and an acetate salt.

名称と識別子

優先名称
Barium acetate
IUPAC
barium(2+) diacetate

名称と別名

Barium acetate543-80-6Barium diacetateACETIC ACID, BARIUM SALTOctan barnatyAcetic Acid Barium Saltbarium(2+) diacetateCaswell No. 068ACCRIS 7240UNII-FBA31YJ60REINECS 208-849-0FBA31YJ60R
名称をさらに表示
NSC 75794barium(II) acetateBARYTA ACETICAAcetic acid barium salt (2:1)DTXSID7020130CHEBI:190441NSC-75794Dibarium diacetate

データベース識別子

CAS
543-80-6
PubChem CID
10980
DTXSID
DTXSID7020130
ChEBI
CHEBI:190441
UNII
FBA31YJ60R
EC Number
208-849-0
Nikkaji
J422G

物性

構造計算による物性

極性表面積
80.3 Ų
水素結合供与体数
0
水素結合受容体数
4
回転可能結合数
0
重原子数
9

実験および物理化学的性質

Chemical ClassesMetals -> Organic Acids, Metal Salts
Density · 2 件

2.47 g/cm³

2.468 @25 °C

SolubilitySolubility in water, g/100ml at 20 °C: 59
Food Contact SubstancesFCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR
Physical Description · 3 件

Dry Powder

White solid; [Hawley] White crystals, soluble in water; [MSDSonline]

WHITE CRYSTALS OR POWDER.

安全と法規制

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 0.3% (1 of 287) of reports.

Warning

H302 (99.7%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P270, P271, P301+P317, P304+P340, P317, P330, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 287 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

危険有害性情報

Regulatory Information · 4 件

Chemical: Acetic acid, barium salt

Acetic acid, barium salt (2:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Acetic acid, barium salt (2:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 16-06-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/24153

Barium acetate: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationEvaluation - Chemicals that are unlikely to require further regulation to manage risks to human health
Fire HazardsNot combustible.
Hazards SummaryCan cause hypokalemia, cardiac arrhythmias, and muscular paralysis; [ICSC] Harmful by ingestion or inhalation; Oral LD50 (rat) = 921 mg/kg; [MSDSonline] See Barium.
EC ClassificationSymbol: Xn; R: 20/22; S: (2)-28; Note: A
UN ClassificationUN Hazard Class: 6.1; UN Pack Group: III

安全と保護具

Fire FightingIn case of fire in the surroundings, use appropriate extinguishing media.
First Aid Measures · 4 件

Fresh air, rest.

Rinse and then wash skin with water and soap.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Refer for medical attention .

Safe StorageSeparated from strong oxidants, acids and food and feedstuffs.
Exposure Control and Personal Protection0.5 [mg/m3], as Ba, inhalable fraction(soluble compds)[German Research Foundation (DFG)]
Spillage Disposal · 1 件

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

Eye PreventionWear safety spectacles.

毒性情報

TreatmentIntravenous infusion of potassium often relieves many of the symptoms of barium toxicity. (L214)
Health Effects · 1 件

The health effects of the different barium compounds depend on how well the compound dissolves in water or the stomach contents. At low doses, barium acts as a muscle stimulant, while higher doses affect the nervous system, causing cardiac irregularities, tremors, weakness, anxiety, dyspnea, paralysisand possibly death. Barium may also cause gastrointestinal disturbances, damage the kidneys and cause decreases in body weight. (L214)

Adverse EffectsACGIH Carcinogen - Not Classifiable.
Exposure Routes · 2 件

The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

Oral (L214) ; inhalation (L214)

Toxicity Summary · 1 件

Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to intracellular compartments. The intracellular translocation of potassium results in a decreased resting membrane potential, making the muscle fibers electrically unexcitable and causing paralysis. Some of these barium's effects may also be due to barium induced neuromuscular blockade and membrane depolarization. (L214)

Signs and Symptoms · 2 件

Abdominal pain. Diarrhoea. Nausea. Vomiting. Weakness. Shortness of breath.

Ingesting excess barium may cause vomiting, abdominal cramps, diarrhea, difficulties in breathing, increased or decreased blood pressure, numbness around the face, and muscle weakness. High levels may result in changes in heart rhythm or paralysis and possibly death. (L214)

化学と産業

薬理情報

Metabolism/Metabolites · 1 件

Barium compounds are absorbed via ingestion and inhalation, the extent of which depends on the individual compound. In the body, the majority of the barium is found in the bone, while small amounts exists in the muscle, adipose, skin, and connective tissue. Barium is not metabolized in the body, but it may be transported or incorporated into complexes or tissues. Barium is excreted in the urine and faeces. (L214)

用途と製造

Uses · 3 件

Used as a chemical reagent; to make other acetates; as a textile mordant; in paint and varnish driers; [Hawley] Used as a lubricant and catalyst; [Merck Index]

Painting (Pigments, Binders, and Biocides) [Category: Paint]

Use (kg; approx.) in Germany (2009): >75000

U.S. Production2023: 352,736 lb
Consumer UsesCatalyst
Industry UsesCatalyst
General Manufacturing Information · 2 件

Not Known or Reasonably Ascertainable

Acetic acid, barium salt (2:1): ACTIVE

関連反応

7 件

関連ノート

読み込み中…