7-ヒドロキシ-3H-フェノキサジン-3-オン10-オキシド

Resazurin

HCID 11077CAS 550-82-3

部分構造検索類似構造を探す

基本情報

標準SMILES: O=c1ccc2[n+]([O-])c3ccc(O)cc3oc-2c1
InChIKey: PLXBWHJQWKZRKG-UHFFFAOYSA-N
分子式: C12H7NO4
平均分子量: 229.19 g/mol
単同位体質量: 229.0375077

概要

Resazurin is a phenoxazine.

名称と識別子

優先名称: Resazurin
IUPAC: 7-hydroxy-10-oxidophenoxazin-10-ium-3-one
現地名: 7-ヒドロキシ-3H-フェノキサジン-3-オン10-オキシド
英語名: RESAZURIN
分子式: C12H7NO4
分子量: 229.19

名称と別名

RESAZURIN550-82-3DiazoresorcinolAzoresorcinResazoinResazurine7-Hydroxy-3H-phenoxazin-3-one 10-oxide3H-Phenoxazin-3-one, 7-hydroxy-, 10-oxideRHODALUXDTXSID40602801FN9YD6968NSC-10438

名称をさらに表示

レサゾインジアゾレソルシノールレサズリンアラマルブルー3-オキソ-7-ヒドロキシ-3H-フェノキサジン10-オキシド7-ヒドロキシ-3H-フェノキサジン-3-オン10-オキシドアゾレソルシン7-ヒドロキシ-3-オキソ-3H-フェノキサジン10-オキシドアラマーブルー7-ヒドロキシ-3-オキソ-3H-フェノキサジン-10-イウム-10-オラート3-ヒドロキシ-7-オキソ-7H-フェノキサジン-10-オキシドNsc 56323Nsc 10438DiazoresorcinalResazurin tablets7-HYDROXY-10-OXY-PHENOXAZIN-3-ONE7-hydroxy-3h-fenoxazin-3-on-10-oxid7-hydroxy-3h-phenoxazin-3-on10-oxide

NSC-563237-hydroxy-10-oxido-phenoxazin-10-ium-3-onereazurinreazurineAlamarblueRefChem:178890DTXCID3041823208-987-1

データベース識別子

CAS: 550-82-3
PubChem CID: 11077
DTXSID: DTXSID4060280
ChEMBL: CHEMBL1616414
ChEBI: CHEBI:8806
UNII: 1FN9YD6968
EC Number: 208-987-1
Nikkaji: J13.744H

物性

構造計算による物性

XLogP: -0.1
極性表面積: 75.3 Å²
水素結合供与体数: 1
水素結合受容体数: 4
回転可能結合数: 0
重原子数: 17
形式電荷: 0
複雑度: 463

実験および物理化学的性質

Chemical ClassesDyes -> Azine Dyes

Physical DescriptionDark red solid with a greenish luster; [Merck Index] Red odorless crystals; [Carolina Biological Supply MSDS]

物理化学的性質

融点: 250 °C · >250°C
沸点: 477.2 · 477.2±55.0 °C(Predicted)
比重(密度): 1.57 · 1.57±0.1 g/cm3(Predicted)
溶解性: 溶解度水、エーテルに不溶。エタノールにやや溶けにくい
酸解離定数(Pka): 6.71 · 6.71(at 25℃)
色: 緑がかった光沢のある暗赤色の結晶
主な用途: 表示装置、インク、洗剤、土壌サンプルの分析、化粧品、果物の鮮度測定、果物の鮮度確認アッセイ、ソルビトール、糖損失のモニタリング、微生物の評価、細胞のアッセイ、ミトコンドリア、精液の質、抗ウイルス物質の検出、細菌および真菌感染症の診断、肺結核の治療、口腔ケア製剤
EPAの化学物質情報: Resazurin (550-82-3)

安全と法規制

GHS分類

GHS Classification · 5 件

This chemical does not meet GHS hazard criteria for 7.3% (3 of 41) of reports.

Warning

H315 (92.7%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 41 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危険有害性情報

Regulatory Information · 2 件

Chemical: 3H-Phenoxazin-3-one, 7-hydroxy-, 10-oxide

3H-Phenoxazin-3-one, 7-hydroxy-, 10-oxide: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazards SummaryA skin irritant; Harmful by ingestion; [Carolina Biological Supply MSDS]

Hazard Classes and CategoriesSkin Irrit. 2 (92.7%)

安全データ

tsca: TSCA listed

化学と産業

薬理情報

MeSH Pharmacological Classification · 1 件

Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)

用途と製造

UsesUsed as a pH indicator, to detect hyposulfite, and in food research (reductase test); [Merck Index]

General Manufacturing Information3H-Phenoxazin-3-one, 7-hydroxy-, 10-oxide: ACTIVE

応用分野

使用As indicator, using a solution of 0.1 g in 20 ml 0.1N NaOH, and water to make 500 ml. pH: 3.8 orange, 6.5 dark violet. In the detection of hyposulfite (sulfoxylate). In food research (reductase test).