基本情報
- CAS
550-83-4- 標準SMILES
CCCOc1cc(N)ccc1C(=O)OCCN(CC)CC.Cl- InChIKey
GITPCGSPKUQZTE-UHFFFAOYSA-N- 分子式
- C16H27ClN2O3
- 平均分子量
- 330.8 g/mol
- 単同位体質量
- 330.1710204
概要
Propoxycaine Hydrochloride is the hydrochloride salt form of propoxycaine, a para-aminobenzoic acid ester with local anesthetic activity. Propoxycaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. This results in a loss of sensation.
名称と識別子
- 優先名称
- Propoxycaine Hydrochloride
- IUPAC
- 2-(diethylamino)ethyl 4-amino-2-propoxybenzoate;hydrochloride
名称と別名
Propoxycaine hydrochloride550-83-4Propoxycaine HClRavocaine hydrochlorideDTXSID6045325NSC-760044Blockain HydrochlorideK490D39G46DTXCID4025325Propoxycaine hydrochloride (USP)Propoxycaine hydrochloride [USP]RefChem:176453
名称をさらに表示
Hydrochloride, Propoxycaine208-988-7Propoxycaine (hydrochloride)Propoxycainehydrochloride2-(diethylamino)ethyl 4-amino-2-propoxybenzoate;hydrochloride2-(Diethylamino)ethyl 4-amino-2-propoxybenzoate monohydrochloride2-(Diethylamino)ethyl 4-amino-2-propoxybenzoate hydrochloridePravocaine hydrochloride
データベース識別子
- CAS
550-83-4- PubChem CID
- 11078
- DTXSID
DTXSID6045325- ChEMBL
CHEMBL1769- UNII
- K490D39G46
- EC Number
- 208-988-7
物性
構造計算による物性
- 極性表面積
- 64.8 Ų
- 水素結合供与体数
- 2
- 水素結合受容体数
- 5
- 回転可能結合数
- 10
- 重原子数
- 22
- 形式電荷
- 0
- 複雑度
- 295
実験および物理化学的性質
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
化学と産業
薬理情報
MeSH Pharmacological Classification
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.
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