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2,6-ジメチルモルホリン
2,6-ジメチルモルホリン · 2,6-DIMETHYLMORPHOLINE · 2,6-Dimethyl-2,3,5,6-tetrahydro-4H-1,4-oxazine · AKOS BBS-00004469 · Dimethylmorpholine · 2,6-Dimethylmorfolin · 2,6-dimethymorpholine · *Dodemorph Impurity 9
識別子と物理属性
| CAS No. | 141-91-3 |
|---|---|
| 分子式 | C6H13NO |
| 平均分子量 | 115.17 g/mol |
| 単同位体質量 | 115.09971404 g/mol |
| SMILES | CC1CNCC(C)O1 |
| InChIKey | HNVIQLPOGUDBSU-UHFFFAOYSA-N |
| PubChem CID | 110862 |
| EC No. | 205-509-3 |
| DTXSID | DTXSID6022002 |
| 現地名 | 2,6-ジメチルモルホリン |
化学・物理的性質
| XLogP | 0.3 |
|---|---|
| 極性表面積 | 21.3 |
| 水素結合供与体数 | 1 |
| 水素結合受容体数 | 2 |
| 回転可能結合数 | 0 |
| 重原子数 | 8 |
| 形式電荷 | 0 |
| 複雑度 | 66.9 |
| 物質分類 | Nitrogen Compounds -> Morpholines |
| SpringerMaterials Properties | Chemical shift |
| 農薬 | Environmental transformation -> Pesticide transformation products (metabolite, successor) |
| 密度 | 0.9346 at 68 °F (NTP, 1992) - Less dense than waterwill float0.9346 @ 20 °C/20 °C0.935 g/mL at 25 °C(lit.) |
| Color/Form | LIQUID |
| 溶解度 | greater than or equal to 0.1 mg/mL at 66 °F (NTP, 1992)SOL IN ALL PROPORTIONS WITH WATER, ALCOHOL, BENZENE, PETROLEUM ETHERSOL IN ACETONEChloroform (Sparingly), Methanol (Slightly)>=0.01 g/100 mL で 19 ºC |
| 引火点 | 112 °F (NTP, 1992)112 °F (44 °C) OC120 °F |
| 沸点 | 297 °F at 760 mmHg (NTP, 1992)146.6 °C @ 760 MM HG147 °C(lit.) |
| 融点 | -121 °F (NTP, 1992)FREEZING POINT: -85 °C−85 °C(lit.) |
| 蒸気密度 | 4 (NTP, 1992) - Heavier than airwill sink (Relative to Air) |
| 屈折率 | INDEX OF REFRACTION: 1.4460 @ 20 °C/Dn20/D 1.446(lit.) |
| Physical Description | 2,6-dimethyl morpholine is a clear liquid. (NTP, 1992)[CAMEO] |
| 外観・状態 | Oil |
| pKa（酸解離定数） | 9.04±0.60(Predicted) |
| 色 | Colourless |
| BRN | 103036 |
| 安定性 | 安定。酸化剤、強酸とは相容れない。可燃性。 |
| InChI | 1S/C6H13NO/c1-5-3-7-4-6(2)8-5/h5-7H,3-4H2,1-2H3 |
| InChIKey | HNVIQLPOGUDBSU-UHFFFAOYSA-N |
| SMILES | CC1CNCC(C)O1 |
| LogP（分配係数） | -0.100 (est) |
| CAS データベース | 141-91-3(CAS DataBase Reference) |
| NISTの化学物質情報 | Morpholine, 2,6-dimethyl-(141-91-3) |
| EPAの化学物質情報 | 2,6-Dimethylmorpholine (141-91-3) |
化学的特性
colourless liquid
安全性と法規制
| GHS 分類 | DangerH226 (100%): Flammable liquid and vapor [Warning Flammable liquids]P210, P233, P240, P241, P242, P243, P260, P262, P264, P264+P265, P270, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P321, P330, P361+P364, P362+P364, P363, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 213 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| 規制情報 | Chemical: Morpholine, 2,6-dimethyl-Status: Active Update: 17-05-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/16356 |
| 輸送ラベル（DOT） | Flammable Liquid Poison |
| 火災危険 | This chemical is combustible. (NTP, 1992) |
| 火災の可能性 | MODERATE FIRE RISK |
| 健康有害性 | SYMPTOMS: Symptoms of exposure to this chemical may include local irritation of the eyes and skin. |
| 有害性の概要 | External application to rabbit eyes scored 7 on a scale of 1-10 (10 being most severe)Emergency treatment: Morpholine[HSDB] A mild skin and severe eye irritant[RTECS] See Morpholine. |
| 反応性グループ | Amines, Phosphines, and Pyridines |
| Reactivity Alerts | Highly Flammable |
| Reactivity Profile | 2,6-DIMETHYL MORPHOLINE reacts with oxidizing agents (NTP, 1992). Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides. |
| Air and Water Reactions | Highly flammable. Very slightly water soluble. |
| NFPA Hazard Classification | 2 - Materials that, under emergency conditions, can cause temporary incapacitation or residual injury.2 - Materials that must be moderately heated or exposed to relatively high ambient temperatures before ignition can occur. Materials would not under normal conditions form hazardous atmospheres with air, but under high ambient temperatures or under moderate heating could release vapor in sufficient quantities to produce hazardous atmospheres with air.0 - Materials that in themselves are normally stable, even under fire conditions. |
| Hazard Classes and Categories | Flam. Liq. 3 (100%) |
| 消火 | Fires involving this material should be controlled using a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992) |
| 応急処置 | EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. |
| 消火手順 | "ALCOHOL" FOAM |
| 非火災時の漏出対応 | SMALL SPILLS AND LEAKAGE: If you should spill this chemical, use absorbent paper to pick up all liquid spill material. Seal the absorbent paper, as well as any of your clothing which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Wash any surfaces you may have contaminated with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. |
| Isolation and Evacuation | Excerpt from ERG Guide 131 [Flammable Liquids - Toxic]: |
| Personal Protective Equipment (PPE) | RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992) |
| Non-Human Toxicity Excerpts | 2,6-DIMETHYLMORPHOLINE RATED 7 ON RABBIT EYES. MOST SEVERE INJURIES HAVE BEEN RATED 10. |
| Toxicity Data | LC (rat) > 4,000 ppm/4h |
| 水環境危害等級（WGK） | 2 |
| TSCA 収載状態 | TSCA listed |
| RTECS 番号 | QE1750000 |
| 輸送番号（UN） | UN 1992 3/PG 3 |
| 税関コード | 29349990 |
| 危険文句（R） | 10-21-41 |
| 危険表示 | Xn |
| 安全措置（S） | 16-26-36/37/39-45 |
| 危険等級 | 3Acute Tox. 4 DermalAcute Tox. 4 OralFlam. Liq. 3Skin Corr. 1B |
| 包装等級 | III |
| 貯蔵分類 | 3 - Flammable liquids |
| 有害物質データ | 141-91-3(Hazardous Substances Data) |
用途
使用
cis-2,6-Dimethylmorpholine (DMMP) has been used in the preparation of microporous material composed of hybrid T2 and T3 supertetrahedral clusters.
一般的な説明
Clear liquid.