酢酸銀(I)
アセトキシ銀(I) · 酢酸銀(I) · 酢酸銀 · 酢酸銀（Ⅰ） · 酢酸銀 PURUM P.A.,≥99.0% (T) · 酢酸銀 REAGENTPLUS,99% · 酢酸銀, 99.9% · AgOAc
識別子と物理属性
| CAS No. | 563-63-3 |
|---|---|
| 分子式 | AgC2H3O2 |
| 平均分子量 | 166.91 g/mol |
| 単同位体質量 | 165.91840134 g/mol |
| SMILES | CC(=O)[O-].[Ag+] |
| InChIKey | CQLFBEKRDQMJLZ-UHFFFAOYSA-M |
| PubChem CID | 11246 |
| ChEMBL | CHEMBL4464576 |
| EC No. | 209-254-9 |
| DTXSID | DTXSID8032041 |
| 現地名 | 酢酸銀(I) |
化学・物理的性質
| 極性表面積 | 40.1 |
|---|---|
| 水素結合供与体数 | 0 |
| 水素結合受容体数 | 2 |
| 回転可能結合数 | 0 |
| 重原子数 | 5 |
| 形式電荷 | 0 |
| 複雑度 | 25.5 |
| 物質分類 | Metals -> Organic Acids, Metal Salts |
| 密度 | 3.26 at 68 °F (USCG, 1999) - Denser than waterwill sink3.25 |
| Physical Description | Silver acetate is a white crystalline plates. Light sensitive. Density 3.26 g / cm3.LiquidOther SolidWhite to slightly gray solidSoluble in 100 parts cold water[Merck Index] Solubility in water = 10 g/L[ChemIDplus] Beige powder[Aldrich MSDS] |
| 融点 | decomposes [STR93] |
| 貯蔵条件 | Store below +30°C. |
| 溶解度 | 10.2g/リットル10.2g/L(20℃) |
| 外観・状態 | 粉体・固形 |
| 色 | 白から灰色 |
| 比重 | 3.259 |
| Merck | 14,8505 |
| BRN | 3595636 |
| 安定性 | 安定性 安定していますが、光に敏感です。強力な還元剤とは相容れない。 |
| InChI | 1S/C2H4O2.Ag/c1-2(3)4/h1H3,(H,3,4)/q+1/p-1 |
| InChIKey | CQLFBEKRDQMJLZ-UHFFFAOYSA-M |
| SMILES | CC(O[Ag])=O |
| CAS データベース | 563-63-3(CAS DataBase Reference) |
| NISTの化学物質情報 | Silver acetate(563-63-3) |
| EPAの化学物質情報 | Silver acetate (563-63-3) |
化学的特性
Off-White/Brown Crystalline Powder
安全性と法規制
| GHS 分類 | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 57 reports by companies from 14 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| 規制情報 | Chemical: Acetic acid, silver(1+) saltAcetic acid, silver(1+) salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Acetic acid, silver(1+) salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Silver acetate: Does not have an individual approval but may be used under an appropriate group standard |
| 健康有害性 | Inhalation of dust irritates nose and throat. Contact with eyes or skin causes irritation. If continued for a long period, ingestion or inhalation of silver compounds can cause permanent discoloration of skin (argyria). (USCG, 1999) |
| 有害性の概要 | Sensitive to light[Merck Index] No evidence of developmental toxicity or teratogenicity in rats dosed by gavage on gestation days 6-19 (even at doses maternally toxic)NOAEL for maternal toxicity was 10 mg/kg/day and 100 mg/kg/day for developmental toxicity[NTP] Dust is irritating to eyes, nose, and throatSolid irritates skin and eyes[CHRIS] Caused effects to metabolism and plasma proteins in 4-day intermittent study of rats (641 mg/kg)[RTECS] A skin and strong eye irritantMay cause argyria[Aldrich MSDS] See Silver. |
| 反応性グループ | Salts, Basic |
| Reactivity Profile | SILVER ACETATE is freely soluble in dilute nitric acid [Merck]. Can serve as an oxidizing agent. |
| Air and Water Reactions | Slightly soluble in water. |
| Hazard Classes and Categories | Skin Irrit. 2 (100%) |
| 応急処置 | INHALATION: move to fresh air. |
| 暴露管理・個人防護 | 0.01 [mg/m3], inhalable fraction, as Ag (salts)[German Research Foundation (DFG)] |
| Threshold Limit Values (TLV) | 0.01 [mg/m3], as Ag (sol. compds.) |
| Permissible Exposure Limit (PEL) | 0.01 [mg/m3], as Ag (sol. compds.) |
| Personal Protective Equipment (PPE) | Dust maskgoggles or face shieldprotective gloves (USCG, 1999) |
| Immediately Dangerous to Life or Health (IDLH) | 10 mg Ag/m3 (NIOSH, 2024)10.0 [mg/m3], as Ag |
| 健康影響 | Silver itself is not toxic to humans, but most silver salts are. In large doses, silver and compounds containing it can be absorbed into the circulatory system and become deposited in various body tissues, leading to argyria, which results in a blue-grayish pigmentation of the skin, eyes, and mucous membranes. Argyria is rare, and although, so far as known, this condition does not otherwise harm a person's health, it is disfiguring and usually permanent. Mild forms of argyria are sometimes mistaken for cyanosis. (L809) |
| 暴露経路 | Oral (L808)inhalation (L808)dermal (L808) |
| 毒性の概要 | Metallic silver is oxidized and may deposit in the tissues, causing arygria. The silver ion is known to inhibit glutathione peroxidase and NA+,K+-ATPase activity, disrupting selenium-catalyzed sulfhydryl oxidation-reduction reactions and intracellular ion concentrations, respectively. Silver nanoparticles are believed to disrupt the mitochondrial respiratory chain, causing oxidative stress, reduced ATP synthesis, and DNA damage. (L808, A243, A244, A245, A246) |
| Signs and Symptoms | Exposure to high levels of silver for a long period of time may result in a condition called arygria, a blue-gray discoloration of the skin and other body tissues. Argyria is a permanent effect but does not appear to be harmful to health. Exposure to high levels of silver in the air has resulted in breathing problems, lung and throat irritation, and stomach pains. Skin contact with silver can cause mild allergic reactions such as rash, swelling, and inflammation in some people. (L808) |
| Carcinogen Classification | No indication of carcinogenicity to humans (not listed by IARC). |
| F | 8 |
| 水環境危害等級（WGK） | 3 |
| TSCA 収載状態 | TSCA listed |
| RTECS 番号 | AJ4100000 |
| 輸送番号（UN） | 1759 |
| PRTR法 | 第1種指定化学物質 |
| 税関コード | 28432900 |
| 危険文句（R） | 36/37/38-50 |
| 化審法 | 2-693 |
| 危険表示 | Xi,N |
| 安全措置（S） | 26-36-37/39-61 |
| 危険等級 | 9Aquatic Acute 1Eye Irrit. 2Skin Irrit. 2STOT SE 3 |
| 毒劇物取締法 | III |
| 貯蔵分類 | 11 - Combustible Solids |
用途
用途
酢酸銀(I)（さくさんぎん いち、英: silver(I) acetate）は、主に農薬として使われる感光性の物質である。タバコの煙と反応して不快臭が生まれるので、禁煙補助のチューインガムに使われている。
用途
アクリル繊維染色改良剤，農薬原料。
用途
ファインセラミックスの製造原科。
説明
Silver acetate is an organic compound with the empirical formula CH3COOAg (or AgC2H3O2). It is a photosensitive, white crystalline solid. It is a useful reagent in the laboratory as a water soluble source of silver lacking an oxidizing anion. It has been used in some antismoking drugs.
使用
In the health field, silver acetate-containing products have been used in gum, spray, and lozenges to deter smokers from smoking. The silver in these products, when mixed with smoke, creates an unpleasant metallic taste in the smoker's mouth, thus deterring them from smoking. Lozenges containing 2.5 mg of silver acetate showed "modest efficacy" on 500 adult smokers tested over a three-month period. However, over a period of 12 months, prevention failed. In 1974, silver acetate was first introduced in Europe as an over-thecounter smoking-deterrent lozenge (Repaton) and then three years later as a chewing gum (Tabmint).
一般的な説明
White crystalline plates. Light sensitive. Density 3.26 g / cm3.
製法・合成法
純化方法
Shake it with acetic acid for three days, and the process is repeated with fresh acid. The solid is then dried in a vacuum oven at 40o for 48hours. It has also been recrystallised from water containing a trace of acetic acid, and dried in air. Store it in the dark. [Beilstein 2 IV 112.]