基本情報
- CAS
14545-72-3- 標準SMILES
O=[N+]([O-])OCl- InChIKey
XYLGPCWDPLOBGP-UHFFFAOYSA-N- 分子式
- ClNO3
- 平均分子量
- 97.46 g/mol
- 単同位体質量
- 96.95667054
概要
Chlorine nitrate is a nitrate of chlorine. It is an important atmospheric gas present in the stratosphere. Nitrite is a toxic compound known to cause methemoglobinemia. (L1137, L1623)
名称と識別子
- 優先名称
- Nitryl hypochlorite ((NO2)(ClO))
- IUPAC
- chloro nitrate
- 現地名
- ニトロオキシクロリド
- 英語名
- Nitric acid chlorine salt
- 分子式
- ClNO3
- 分子量
- 97.46
名称と別名
14545-72-3DTXSID00163043Nitryl hypochlorite ((NO2)(ClO))RefChem:1092480DTXCID5085534Chlorine nitratechloro nitrateNitric acid chlorine saltChlornitratNitryl hypochlorite ((NO2)(OCl))ClONO2SCHEMBL3028453
名称をさらに表示
次亜塩素酸ニトリルニトロキシクロリドクロロニトラートニトロオキシクロリド硝酸塩素クロロ ニトラートChloronitrateNitroxychlorideNitrooxy chlorideNitryl hypochloriteNitryl hypochlorite ((NO2)(ClO)) (9CI)
(Chlorooxy)di(oxo)-lambda~5~-azaneQ2563692
データベース識別子
- CAS
14545-72-3- PubChem CID
- 114934
- DTXSID
DTXSID00163043- Nikkaji
- J306.732G
物性
構造計算による物性
- XLogP
- 1.3
- 極性表面積
- 55.1 Ų
- 水素結合供与体数
- 0
- 水素結合受容体数
- 3
- 回転可能結合数
- 0
- 重原子数
- 5
- 形式電荷
- 0
- 複雑度
- 36.6
実験および物理化学的性質
SpringerMaterials PropertiesCoriolis coupling
物理化学的性質
- 融点
- -107 °C · -107°C
- 沸点
- 18 °C · 18°C
- 外見
- Colorless to pale yellow, mobile liquid
- Henry's Law Constant
- 7 · 7.0×10-2 mol/(m3Pa) at 25℃, Robinson et al. (1997)
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
毒性情報
Treatment
Methemoglobinemia can be treated with supplemental oxygen and methylene blue 1% solution administered intravenously slowly over five minutes followed by IV flush with normal saline. Methylene blue restores the iron in hemoglobin to its normal (reduced) oxygen-carrying state. (L1613)
Health EffectsNitrate and nitrite poisoning causes methemoglobinemia. Nitrites may cause pregnancy complications and developmental effects. They may also be carcinogenic. (L1137)
Exposure RoutesOral (L1137) ; inhalation (L1137)
Toxicity Summary
Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and methemoglobin. This elevation of methemoglobin levels is a condition known as methemoglobinemia, and is characterized by tissue hypoxia, as methemoglobin cannot bind oxygen. (A2450, L1613)
Signs and Symptoms
Nitrate and nitrite poisoning causes methemoglobinemia. Symptoms include cyanosis, cardiac dysrhythmias and circulatory failure, and progressive central nervous system (CNS) effects. CNS effects can range from mild dizziness and lethargy to coma and convulsions. (L1137)
Carcinogen ClassificationIngested nitrate or nitrite under conditions that result in endogenous nitrosation is probably carcinogenic to humans (Group 2A). (L135)
化学と産業
薬理情報
Metabolism/Metabolites
Intake of some amount of nitrates and nitrites is a normal part of the nitrogen cycle in humans. In vivo conversion of nitrates to nitrites can occur in the gastrointestional tract under the right conditions, significantly enhancing nitrates' toxic potency. The major metabolic pathway for nitrate is conversion to nitrite, and then to ammonia. Nitrites, nitrates, and their metabolites are excreted in the urine. (L1137)
調製方法
A refrigerated pocket-shaped receiver is used to sublime an excess of N2O5 directly onto Cl2O in a high vacuum. The receiver containing the Cl2O (equivalent to 5 ml of liquid) is placed in liquid nitrogen so that only the portion holding the Cl2O is cooled, and the N2O5 thus deposits on the Cl2O as a solid. After releasing the vacuum, the receiver is removed from the high-vacuum apparatus, closed off using a drying tube, and placed in a refrigerating bath at —78°C. While the bath is slowly warmed to between —20 and 0°C (over 15 hours), the components react slowly. The ClNO3 thus formed is still contaminated with chlorine (an impurity of the Cl2O) and excess N2O5. To eliminate the chlorine, which is difficult to separate, the reaction product is heated to 30°C in a water bath and refluxed for one hour. The upper half of the reaction vessel (serving as a condenser) is cooled by a ring-shaped cup filled with Dry Ice. The chlorine is volatilized in this procedure, while the excess N2O5 is decomposed to NO2 and O2. The ClNO3 is then distilled at — 90°C in a high vacuum, leaving behind the NO2.Cl2O+N2O5=2ClNO3
補足説明
定義A compound that slows the rate of destruction of ozone.
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