(αS)-α-ヒドロキシ-α-(ヒドロキシメチル)ベンゼン酢酸(1R,2R,4S,5S,7α)-9-メチル-3-オキサ-9-アザトリシクロ[3.3.1.02,4]ノナ-7-イル

説明Anisodine is isolated from the roots of the plant Solanaceae Anisodus tanguticus (Maxim.) Pasch. (Scopolia tangutica Maxim.), which has a common name of Zhang-Liu-Shen, growing at the plateau with an altitude of 1700–4300m and richly distributed in Tibet, Sichuan, Qinghai, Gansu, and other provinces in China.

来歴Anisodine hydrobromide was an originally created new drug in China. It was separated from the herbal medicine Anisodus tanguticus from Qinghai province. In the early 1960s, Anisodus tanguticus was given the common name of Zhang-Liu-Shenin Qinghai province, similar to the common name Zhang Liu of Radix Phytolaccae. As a result, the root was misused as Radix Phytolaccae until the occurrence of atropine poisoning symptoms. Histological identification found that it is Anisodus tanguticus (Maxim.) Pasch, not Radix Phytolaccae. In order to make full use of the wild plant’s resources and develop the products of henbane drugs in China, the Chinese Academy of Medical Sciences carried out the systemic research on the plant .