化工社化工社 化学情報印刷レポート · 研究参考用
フッ化メチル
メチルフルオリド · フロン41 · フレオン41 · フルオロメタン · フッ化メチル（HFC-41） · フルオロメタン、 · 地球温暖化物質（京都議定書） · フッ化メチル
識別子と物理属性
| CAS No. | 13453-52-6 |
|---|---|
| 分子式 | CH3F |
| 平均分子量 | 34.033 g/mol |
| 単同位体質量 | 34.02187826 g/mol |
| SMILES | CF |
| InChIKey | NBVXSUQYWXRMNV-UHFFFAOYSA-N |
| PubChem CID | 11638 |
| ChEMBL | CHEMBL116838 |
| ChEBI | CHEBI:28826 |
| EC No. | 209-796-6 |
| DTXSID | DTXSID6060474 |
| 現地名 | フッ化メチル |
化学・物理的性質
| XLogP | 0.6 |
|---|---|
| 極性表面積 | 0 |
| 水素結合供与体数 | 0 |
| 水素結合受容体数 | 1 |
| 回転可能結合数 | 0 |
| 重原子数 | 2 |
| 形式電荷 | 0 |
| 複雑度 | 2 |
| 密度 | 0.557 @25 °C0,877 g/cm3 |
| 沸点 | -78.4 °C @760 [mm Hg]-79°C |
| 融点 | -143.3 °C-115°C |
| 蒸気圧 | 750 [mm Hg] @-78.599999999999994 °C1965-5874kPa at 0-15℃ |
| Physical Description | Methyl fluoride (or fluoromethane) is a colorless flammable gas which is heavier than air. It has an agreeable ether-like odor. It is narcotic in high concentrations. It burns with evolution of hydrogen fluoride. The flame is colorless, similar to alcohol. Under prolonged exposure to fire or intense heat the containers may rupture violently and rocket.CBIGas with a pleasant ether-like odor[Merck Index] Colorless gas[Hawley] Colorless gas with a sweet odor[MSDSonline] |
| Kovats Retention Index | 217173 |
| 屈折率 | 1.1740 |
| 溶解度 | 1.787g/L(29.9℃) |
| 比熱容量 | Cp(gas): 1.1 J/(g·K), at 25℃ |
| ヘンリー定数 | 6.1×10-4 mol/(m3Pa) at 25℃, Burkholder et al. (2019) |
| 安定性 | 安定。非常に可燃性。強力な酸化剤とは相容れない。 |
| LogP（分配係数） | 0.51 at 20℃ and pH7 |
| CAS データベース | 593-53-3(CAS DataBase Reference) |
| EPAの化学物質情報 | HFC-41 (593-53-3) |
化学的特性
colourless gas with an ether-like odour
安全性と法規制
| GHS 分類 | DangerH220 (99.2%): Extremely flammable gas [Danger Flammable gases]H280 (99.2%): Contains gas under pressuremay explode if heated [Warning Gases under pressure]P203, P210, P222, P280, P377, P381, P403, and P410+P403 (click each P-code to see the statement)Aggregated GHS information provided per 129 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| 規制情報 | Methane, fluoro- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Methane, fluoro- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 05-01-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/21114Fluoromethane: HSNO Approval: HSR001007 Approved with controlsThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| 輸送ラベル（DOT） | Flammable Gas |
| 火災危険 | Excerpt from ERG Guide 115 [Gases - Flammable (Including Refrigerated Liquids)]:EXTREMELY FLAMMABLE. Will be easily ignited by heat, sparks or flames. Will form explosive mixtures with air. Vapors from liquefied gas are initially heavier than air and spread along ground. CAUTION: Hydrogen (UN1049), Deuterium (UN1957), Hydrogen, refrigerated liquid (UN1966), Methane (UN1971) and Hydrogen and Methane mixture, compressed (UN2034) are lighter than air and will rise. Hydrogen and Deuterium fires are difficult to detect since they burn with an invisible flame. Use an alternate method of detection (thermal camera, broom handle, etc.) Vapors may travel to source of ignition and flash back. Cylinders exposed to fire may vent and release flammable gas through pressure relief devices. Containers may explode when heated. Ruptured cylinders may rocket. CAUTION: When LNG - Liquefied natural gas (UN1972) is released on or near water, product may vaporize explosively. (ERG, 2024)· EXTREMELY FLAMMABLE.· Will be easily ignited by heat, sparks or flames.· Will form explosive mixtures with air.· Vapors from liquefied gas are initially heavier than air and spread along ground.CAUTION: Hydrogen (UN1049), Deuterium (UN1957), Hydrogen, refrigerated liquid (UN1966), Methane (UN1971) and Hydrogen and Methane mixture, compressed (UN2034) are lighter than air and will rise. Hydrogen and Deuterium fires are difficult to detect since they burn with an invisible flame. Use an alternate method of detection (thermal camera, broom handle, etc.)· Vapors may travel to source of ignition and flash back.· Cylinders exposed to fire may vent and release flammable gas through pressure relief devices.· Containers may explode when heated.· Ruptured cylinders may rocket.CAUTION: When LNG - Liquefied natural gas (UN1972) is released on or near water, product may vaporize explosively. |
| 健康有害性 | Excerpt from ERG Guide 115 [Gases - Flammable (Including Refrigerated Liquids)]:Vapors may cause dizziness or asphyxiation without warning, especially when in closed or confined areas. Some may be irritating if inhaled at high concentrations. Contact with gas, liquefied gas or cryogenic liquids may cause burns, severe injury and/or frostbite. Fire may produce irritating and/or toxic gases. (ERG, 2024)· Vapors may cause dizziness or asphyxiation without warning, especially when in closed or confined areas.· Some may be irritating if inhaled at high concentrations.· Contact with gas, liquefied gas or cryogenic liquids may cause burns, severe injury and/or frostbite.· Fire may produce irritating and/or toxic gases. |
| 有害性の概要 | High concentrations have narcotic effects[Hawley] Extremely flammableCan form explosive mixtures with airIn confined space spill, may displace air and act as simple asphyxiantEvaporating liquid can cause frostbite[CAMEO] May cause flash fireInhalation of high concentrations can cause CNS depression[MSDSonline] |
| 輸送番号・ガイド（DOT） | 2454 115 |
| 反応性グループ | Fluorinated Organic Compounds |
| Reactivity Alerts | Highly Flammable |
| Reactivity Profile | Halogenated aliphatic compounds, such as METHYL FLUORIDE, are moderately or very reactive. Halogenated organics generally become less reactive as more of their hydrogen atoms are replaced with halogen atoms. Low molecular weight haloalkanes are highly flammable and can react with some metals to form dangerous products. Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides. The prolonged mixing of halogenated solvents with metallic or other azides may cause the slow formation of explosive azides, for example methylene chloride and sodium azide, [Chem. Eng. News, 1986, 64(51)]. |
| DOT Hazard Classification | Methyl fluoride, or Refrigerant gas R 41UN2454Div 2.1 Flammable gas (49 eCFR § 173.115) |
| Air and Water Reactions | Highly flammable. It burns in air with evolution of hydrogen fluoride. |
| Hazard Classes and Categories | Flam. Gas 1 (99.2%)Press. Gas (Liq.) (99.2%)Flammable gases (including chemically unstable gases) - Category 1Gases under pressure - High pressure liquefied gasFlammable agents - 3rd degree |
| 消火 | Excerpt from ERG Guide 115 [Gases - Flammable (Including Refrigerated Liquids)]:DO NOT EXTINGUISH A LEAKING GAS FIRE UNLESS LEAK CAN BE STOPPED. CAUTION: Hydrogen (UN1049), Deuterium (UN1957), Hydrogen, refrigerated liquid (UN1966) and Hydrogen and Methane mixture, compressed (UN2034) will burn with an invisible flame. Use an alternate method of detection (thermal camera, broom handle, etc.).SMALL FIRE: Dry chemical or CO2.LARGE FIRE: Water spray or fog. If it can be done safely, move undamaged containers away from the area around the fire. CAUTION: For LNG - Liquefied natural gas (UN1972) pool fires, DO NOT USE water. Use dry chemical or high-expansion foam.FIRE INVOLVING TANKS: Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Cool containers with flooding quantities of water until well after fire is out. Do not direct water at source of leak or safety devicesicing may occur. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. For massive fire, use unmanned master stream devices or monitor nozzlesif this is impossible, withdraw from area and let fire burn. (ERG, 2024) |
| 漏出応急措置 | · CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.· Keep unauthorized personnel away.· Stay upwind, uphill and/or upstream.· Many gases are heavier than air and will spread along the ground and collect in low or confined areas (sewers, basements, tanks, etc.).· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.· All equipment used when handling the product must be grounded.· Do not touch or walk through spilled material.· Stop leak if you can do it without risk.· If possible, turn leaking containers so that gas escapes rather than liquid.· Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled material.· Do not direct water at spill or source of leak.CAUTION: For LNG - Liquefied natural gas (UN1972), DO NOT apply water, regular or alcohol-resistant foam directly on spill. Use a high-expansion foam if available to reduce vapors.· Prevent spreading of vapors through sewers, ventilation systems and confined areas.· Isolate area until gas has dispersed.CAUTION: When in contact with refrigerated/cryogenic liquids, many materials become brittle and are likely to break without warning. |
| 応急処置 | Excerpt from ERG Guide 115 [Gases - Flammable (Including Refrigerated Liquids)]:Refer to the "General First Aid" section. Specific First Aid: Clothing frozen to the skin should be thawed before being removed. In case of contact with liquefied gas, only medical personnel should attempt thawing frosted parts. In case of burns, immediately cool affected skin for as long as possible with cold water. Do not remove clothing if adhering to skin. (ERG, 2024)General First Aid:· Call 911 or emergency medical service.· Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.· Move victim to fresh air if it can be done safely.· Administer oxygen if breathing is difficult.· If victim is not breathing:-- DO NOT perform mouth-to-mouth resuscitationthe victim may have ingested or inhaled the substance.-- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).-- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.· Remove and isolate contaminated clothing and shoes.· For minor skin contact, avoid spreading material on unaffected skin.· In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.· For severe burns, immediate medical attention is required.· Effects of exposure (inhalation, ingestion, or skin contact) to substance may be delayed.· Keep victim calm and warm.· Keep victim under observation.· For further assistance, contact your local Poison Control Center.· Note: Basic Life Support (BLS) and Advanced Life Support (ALS) should be done by trained professionals.Specific First Aid:· Clothing frozen to the skin should be thawed before being removed. |
| 暴露管理・個人防護 | · Wear positive pressure self-contained breathing apparatus (SCBA).· Structural firefighters' protective clothing provides thermal protection but only limited chemical protection.· Always wear thermal protective clothing when handling refrigerated/cryogenic liquids. |
| 非火災時の漏出対応 | Excerpt from ERG Guide 115 [Gases - Flammable (Including Refrigerated Liquids)]:ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. If possible, turn leaking containers so that gas escapes rather than liquid. Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled material. Do not direct water at spill or source of leak. CAUTION: For LNG - Liquefied natural gas (UN1972), DO NOT apply water, regular or alcohol-resistant foam directly on spill. Use a high-expansion foam if available to reduce vapors. Prevent spreading of vapors through sewers, ventilation systems and confined areas. Isolate area until gas has dispersed. CAUTION: When in contact with refrigerated/cryogenic liquids, many materials become brittle and are likely to break without warning. (ERG, 2024) |
| Isolation and Evacuation | Excerpt from ERG Guide 115 [Gases - Flammable (Including Refrigerated Liquids)]:IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area for at least 100 meters (330 feet) in all directions.LARGE SPILL: Consider initial downwind evacuation for at least 800 meters (1/2 mile).FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 1600 meters (1 mile) in all directionsalso, consider initial evacuation for 1600 meters (1 mile) in all directions. In fires involving Liquefied Petroleum Gases (LPG) (UN1075), Butane (UN1011), Butylene (UN1012), Isobutylene (UN1055), Propylene (UN1077), Isobutane (UN1969), and Propane (UN1978), also refer to the "BLEVE - Safety Precautions" section. (ERG, 2024)Immediate precautionary measure· Isolate spill or leak area for at least 100 meters (330 feet) in all directions.· Consider initial downwind evacuation for at least 800 meters (1/2 mile).· If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 1600 meters (1 mile) in all directionsalso, consider initial evacuation for 1600 meters (1 mile) in all directions.· In fires involving Liquefied Petroleum Gases (LPG) (UN1075), Butane (UN1011), Butylene (UN1012), Isobutylene (UN1055), Propylene (UN1077), Isobutane (UN1969), and Propane (UN1978), also refer to the "BLEVE - Safety Precautions" section. |
| Protective Action Criteria (PAC) | 13 [mg/m3]150 [mg/m3]900 [mg/m3] |
| Personal Protective Equipment (PPE) | Excerpt from ERG Guide 115 [Gases - Flammable (Including Refrigerated Liquids)]:Wear positive pressure self-contained breathing apparatus (SCBA). Structural firefighters' protective clothing provides thermal protection but only limited chemical protection. Always wear thermal protective clothing when handling refrigerated/cryogenic liquids. (ERG, 2024) |
| Emergency Response Planning Guidelines | · DO NOT EXTINGUISH A LEAKING GAS FIRE UNLESS LEAK CAN BE STOPPED.CAUTION: Hydrogen (UN1049), Deuterium (UN1957), Hydrogen, refrigerated liquid (UN1966) and Hydrogen and Methane mixture, compressed (UN2034) will burn with an invisible flame. Use an alternate method of detection (thermal camera, broom handle, etc.)Small Fire· Dry chemical or CO2.Large Fire· Water spray or fog.· If it can be done safely, move undamaged containers away from the area around the fire.CAUTION: For LNG - Liquefied natural gas (UN1972) pool fires, DO NOT USE water. Use dry chemical or high-expansion foam.Fire Involving Tanks· Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles.· Cool containers with flooding quantities of water until well after fire is out.· Do not direct water at source of leak or safety devicesicing may occur.· Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.· ALWAYS stay away from tanks in direct contact with flames.· For massive fire, use unmanned master stream devices or monitor nozzlesif this is impossible, withdraw from area and let fire burn. |
| 有害作用 | Neurotoxin - Acute solvent syndromeOther Poison - Simple Asphyxiant |
| TSCA 収載状態 | TSCA listed |
| 輸送番号（UN） | UN 2454 (METHYL FLUORIDE (REFRIGERANT GAS R 41)) |
| 税関コード | 2903430010 |
| 危険文句（R） | 12 |
| 化審法 | 新規公示化学物質（2011年4月1日以降届出） |
| 危険表示 | F,F+ |
| hazard_note | Flammable |
| 安全措置（S） | 16-33 |
| 危険等級 | 2.1 |
用途
解説
fluoromethane．CH3F(34.03)．フッ化メチルは，ヨウ化メチルにフッ化銀を作用させるか，フッ化テトラメチルアンモニウムを熱分解して得られる．エーテル臭の可燃性気体．凝固点－141.8 ℃，沸点－78.4 ℃，臨界温度44.55 ℃．臨界圧力58.0 atm．水1 cm3 に1.66 cm3(15 ℃)溶ける．高濃度では催眠性を示す．塩素ガスと光照射下で反応させるとクロロフルオロメタンを生成する．森北出版「化学辞典（第2版）
用途
主に、スプレー用のガスなどに用いられる。
一般的な説明
METHYL FLUORIDE (or fluoromethane) is a colorless flammable gas which is heavier than air. METHYL FLUORIDE has an agreeable ether-like odor. METHYL FLUORIDE is narcotic in high concentrations. METHYL FLUORIDE burns with evolution of hydrogen fluoride. The flame is colorless, similar to alcohol. Under prolonged exposure to fire or intense heat the containers may rupture violently and rocket.