エタンスルホニルクロリド

Oil

Pale yellow

Soluble in carbon disulfide

Slightly soluble (decomposes) in water and alcohol; very soluble in ether and dichloromethane.

Danger

H302 (96.6%): Harmful if swallowed [Warning Acute toxicity, oral]

P260, P261, P262, P264, P270, P271, P280, P284, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P319, P320, P321, P330, P361+P364, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 58 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Status: Active Update: 06-01-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/11864

Ethanesulphonyl chloride: Does not have an individual approval but may be used under an appropriate group standard

A lachrymator; All rats exposed to 1273 ppm died within 30 to 130 minutes; 4-hr LC50 (rat) = approximately 86 ppm; Rats exposed to lethal concentrations have lacrimation, salivation, gasping, and pulmonary hemorrhage; [HSDB] Reacts violently with water; A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis; Effects in high-dose animal studies include acute pulmonary edema; [MSDSonline]

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

Used to make sulfonyl-substituted imides, methide lithium salts, and pentafluoroethanesulfonyl fluoride, a fluorinated surfactant; [HSDB]

Intermediate in the syntheses of new, low-cost, non-fluorinated, sulfonyl-substituted imide and methide lithium salts.

Intermediate in the preparation of the fluorinated surfactant pentafluoroethanesulfonyl fluoride.

Alkanesulfonyl chlorides are manufactured from mercaptans or disulfides and chlorine using a loop reactor having an ejector, wherein mercaptan or disulfide is dispersed or dissolved into circulating aqueous solvent before the ejector and alowed to react with chlorine supplied through the aspirator of the ejector.

Mercaptans or disulfide in aqueous solvents are reacted with chlorine gas in dark to produce alkanesulfonyl chloride without chloro chain byproducts. Thus, ... ethyl mercaptan was reacted with ... chlorine gas over 4 hours in /the/ dark in ... pure water keeping the reaction temperature under 20 °C to give ethanesulfonyl chloride.