基本情報
- CAS
29915-38-6- 標準SMILES
O=S(=O)(O)CCCNC(CO)(CO)CO- InChIKey
YNLCVAQJIKOXER-UHFFFAOYSA-N- 分子式
- C7H17NO6S
- 平均分子量
- 243.28 g/mol
- 単同位体質量
- 243.07765844
概要
N-[tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid is an organosulfonic acid.
名称と識別子
- 優先名称
- N-(Tris(hydroxymethyl)methyl)-3-aminopropanesulfonic acid
- IUPAC
- 3-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]propane-1-sulfonic acid
- 現地名
- N-トリス(ヒドロキシメチル)メチル-3-アミノプロパンスルホン酸
- 英語名
- TAPS
- 分子式
- C7H17NO6S
- 分子量
- 243.28
名称と別名
29915-38-63-(Tris(hydroxymethyl)methylamino)-1-propanesulfonic acidN-[Tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acidY5DC3IN0663-((2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino)-1-propanesulfonic acidTaps cpd3-[Tris(hydroxymethyl)methylamino]-1-propanesulfonic acidN-(TRIS(HYDROXYMETHYL)METHYL)-3-AMINOPROPANESULFONIC ACID3-[[2-Hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]-1-propanesulfonic acid1-Propanesulfonic acid, 3-((2-hydroxy-1,1-bis(hydroxymethyl)ethyl)amino)-1-Propanesulfonic acid, 3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]-3-{[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino}-1-propanesulfonic acid
名称をさらに表示
N-トリス(ヒドロキシメチル)メチル-3-アミノプロパンスルホン酸3-[[2-ヒドロキシ-1,1-ビス(ヒドロキシメチル)エチル]アミノ]-1-プロパンスルホン酸3-[[1,1-ビス(ヒドロキシメチル)-2-ヒドロキシエチル]アミノ]プロパン-1-スルホン酸N-(3-スルホプロピル)トリス(ヒドロキシメチル)メタンアミン3-[2-ヒドロキシ-1,1-ビス(ヒドロキシメチル)エチルアミノ]-1-プロパンスルホン酸3-[2-ヒドロキシ-1,1-ビス(ヒドロキシメチル)エチルアミノ]プロパン-1-スルホン酸3-[[1,1-ビス(ヒドロキシメチル)-2-ヒドロキシエチル]アミノ]-1-プロパンスルホン酸
物性
構造計算による物性
- XLogP
- -5.4
- 極性表面積
- 135 Ų
- 水素結合供与体数
- 5
- 水素結合受容体数
- 7
- 回転可能結合数
- 8
- 重原子数
- 15
- 形式電荷
- 0
- 複雑度
- 247
実験および物理化学的性質
Chemical ClassesOther Uses -> Biological Buffers
Physical DescriptionSolid; [Merck Index] White crystalline solid; [Sigma-Aldrich MSDS]
物理化学的性質
- 融点
- 230 · 230-235 °C (dec.)
- 比重(密度)
- 1.429 · 1.4290 (rough estimate)
- 屈折率
- 1.637 · 1.6370 (estimate)
- 闪点
- 110 °C · 110 °C
- 貯蔵温度
- Keep in dark place,Sealed in dry,Room Temperature
- 溶解性
- 2 O: · H2O: 1M at20℃、透明、無色
- 外見
- 個体
- 酸解離定数(Pka)
- 8.55 · 8.55; pKa (37°): 8.1; pKa2 (25°): 8.28
- 色
- 白い
- 臭い (Odor)
- 無臭
- PH
- 7.7 · 7.7-9.1
- 水溶解度
- 溶ける
- Merck
- 13 · 13,9148
- BRN
- 2452420 · 2452420
- 安定性
- 安定。強力な酸化剤と相容れない
- 主な用途
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
GHS分類
GHS Classification
This chemical does not meet GHS hazard criteria for 97.6% (120 of 123) of all reports.
Not Classified
Aggregated GHS information provided per 123 reports by companies from 4 notifications to the ECHA C&L Inventory.
危険有害性情報
Regulatory Information
Chemical: 1-Propanesulfonic acid, 3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]-
REACH registered substance: TAPS (EC: 445-030-9)
1-Propanesulfonic acid, 3-2-hydroxy-1,1-bis(hydroxymethyl)ethylamino-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazards SummaryNot considered hazardous by GHS classification;[Sigma-Aldrich MSDS]
Hazard Classes and CategoriesNot Classified
安全と保護具
Protective Action Criteria (PAC)
30 [mg/m3]
330 [mg/m3]
2000 [mg/m3]
安全データ
- wgk
- 3
- tsca
- TSCA listed
- hs_code
- 29221980
- risk_code
- 36/37/38
- hazard_code
- Xi
- safety_code
- 22-24/25-36-26
- hazard_class
- IRRITANT
化学と産業
用途と製造
UsesUsed as a biological buffer; [Merck Index]
General Manufacturing Information1-Propanesulfonic acid, 3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]-: ACTIVE
応用分野
説明TAPS is a zwitterionic buffering agent used in biochemistry and molecular biology. It is part of the Tris family of buffers and is useful for a pH range of 7.7 – 9.1. The members of TRIS family are tris(hydroxymethyl)aminomethane (TRIS), N-[tris(hydroxymethyl)methyl]-2-aminoethanesulfonic acid (TES), N-[tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid (TAPS), N-[tris(hydroxymethyl)methyl]-3-amino-2-hydroxypropanesulfonic acid (TAPSO), and N-tris(hydroxymethyl)methyl-4-aminobutanesulfonic acid (TABS) buffers[1]. The solubilities of TAPS in aqueous solution decrease with increasing concentration of the salts (salting-out effect)[2]. TAPS is the preferred culture media buffer used for dinoflagellate experiments, allowing for minimal pH change and maximal growth. It is also often used in capillary electrophoresis to analyze DNA and in planar chromatography to separate dyes. TAPS may form a complex with some common metals so stability constants and concentrations should be taken into account when choosing this buffer. TAPS is capable of inhibiting connexin channels in animal cells.
使用A zwitterionic Good's Buffer
上流・下流製品情報
上流原料
サプライヤー100 社
国药集团化学试剂有限公司
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