5-(2-((2-(2-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide

HCID 121829
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基本情報

CAS
94666-07-6
標準SMILES
CCOc1ccccc1OCCNC(C)Cc1ccc(OC)c(S(N)(=O)=O)c1
InChIKey
DRHKJLXJIQTDTD-UHFFFAOYSA-N
分子式
C20H28N2O5S
平均分子量
408.5 g/mol
単同位体質量
408.17189317

名称と識別子

優先名称
5-(2-((2-(2-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide
IUPAC
5-[2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide
英語名
(+-)-Tamsulosin
分子式
C20H28N2O5S
分子量
408.51

名称と別名

94666-07-6CHEBI:1425465-(2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl)-2-methoxybenzenesulfonamide5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamideRefChem:529183926-076-3Racemic Tamsulosin(+-)-TamsulosinBenzenesulfonamide, 5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxy-Amsulosin5-[2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide
名称をさらに表示
Zavegepant Impurity 11Tamsulosin Impurity 12 Monomer(Tamsulosin Monomer Racemate)Benzenesulfonamide, 5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-5-[2-[2-(2-ethoxyphenoxy)-ethylamino]-2-methylethyl]-2-methoxybenzenesulfonamideBenzenesulfonamide, 5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy- (9CI)
YM 12617YM-12617Harnal-D5-[2-[2-(2-Ethoxyphenoxy)ethylamino]propyl]]-2-methoxybenzenesulfonamidebenzenesulfonamide, 5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxy-, hydrochlorideTamsolusinSpectrum4_000788SCHEMBL53998

データベース識別子

CAS
94666-07-6
PubChem CID
121829
ChEBI
CHEBI:142546
EC Number
926-076-3
Nikkaji
J330.327F

物性

構造計算による物性

XLogP
2.7
極性表面積
108 Ų
水素結合供与体数
2
水素結合受容体数
7
回転可能結合数
11
重原子数
28

物理化学的性質

沸点
595.5 · 595.5±60.0 °C(Predicted)
比重(密度)
1.191 · 1.191±0.06 g/cm3(Predicted)
酸解離定数(Pka)
10.08 · 10.08±0.60(Predicted)

安全と法規制

GHS分類

GHS Classification · 5 件

Warning

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 2 reports by companies from 1 notifications to the ECHA C&L Inventory.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Regulatory InformationStatus: Active Update: 30-05-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/26184
Hazard Classes and CategoriesAcute Tox. 4 (100%)

法規制情報

Regulatory InformationStatus: Active Update: 30-05-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/26184

化学と産業

薬理情報

MeSH Pharmacological Classification · 2 件

Drugs that bind to and block the activation of ADRENERGIC ALPHA-1 RECEPTORS.

Drugs used in the treatment of urological conditions and diseases such as URINARY INCONTINENCE and URINARY TRACT INFECTIONS.

サプライヤー3 社

TargetMol 中国（陶术生物）400-821-0310 15002144251 · [email protected]
湖北扬信医药科技有限公司15374522761 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354 · [email protected]

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