化工社化工社 化学情報印刷レポート · 研究参考用
クロロプロパノール
クロロプロパノール · Propanol, chloro- · CHLOROPROPANOL, MIXED ISOMERS
識別子と物理属性
| CAS No. | 28064-81-5 |
|---|---|
| 分子式 | C3H7ClO |
| 平均分子量 | 94.54 g/mol |
| 単同位体質量 | 94.01854252 g/mol |
| SMILES | OCCCCl |
| InChIKey | LAMUXTNQCICZQX-UHFFFAOYSA-N |
| PubChem CID | 12313 |
| ChEMBL | CHEMBL1230102 |
| EC No. | 210-992-9 |
| DTXSID | DTXSID9024809 |
| 現地名 | クロロプロパノール |
化学・物理的性質
| XLogP | 0.5 |
|---|---|
| 極性表面積 | 20.2 |
| 水素結合供与体数 | 1 |
| 水素結合受容体数 | 1 |
| 回転可能結合数 | 2 |
| 重原子数 | 5 |
| 形式電荷 | 0 |
| 複雑度 | 16.4 |
| 物質分類 | Other Classes -> Halogenated AlcoholsFlammable agents - 2nd degree |
| SpringerMaterials Properties | Coriolis coupling |
| 密度 | 1.13 to 1.15 at 68 °F (NTP, 1992)1.309 @ 20°C |
| 溶解度 | 50 to 100 mg/mL at 73 °F (NTP, 1992) |
| 引火点 | 164 °F (NTP, 1992) |
| 沸点 | 320 to 329 °F at 760 mmHg (NTP, 1992)165 °C @760 [mm Hg] |
| 蒸気圧 | 1.2 [mmHg] |
| Physical Description | 3-chloropropanol-1 appears as a colorless liquid with a mild odor. Slightly denser than water. Toxic by ingestion and inhalation. Flash point 270 °F. Used to make plastics, resins and other chemicals.[CAMEO] |
| EPAの化学物質情報 | 2-Chloropropanol (28064-81-5) |
安全性と法規制
| GHS 分類 | This chemical does not meet GHS hazard criteria for 38.6% (59 of 153) of reports.WarningH302 (22.9%): Harmful if swallowed [Warning Acute toxicity, oral]P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 153 reports by companies from 21 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| 規制情報 | Chemical: 1-Propanol, 3-chloro-Status: Active Update: 20-10-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/223213-Chloro-1-propanol: Does not have an individual approval but may be used under an appropriate group standardThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| 輸送ラベル（DOT） | Poison |
| 火災危険 | Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:· Combustible material: may burn but does not ignite readily. |
| 健康有害性 | Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:· TOXIC and/or CORROSIVEinhalation, ingestion or skin contact with material may cause severe injury or death. |
| 有害性の概要 | Causes muscle contraction or spasticity, ulceration of the stomach, and other liver changes in oral lethal-dose studies of mice[RTECS] May cause skin, eye, and nasal irritationOther symptoms may include vomiting, giddiness, dizziness, incoordination, visual disturbances, and comaMay be absorbed through skin[NTP] An irritantHarmful by ingestion[Alfa Aesar MSDS] See 1-Chloro-2-propanol. |
| 輸送番号・ガイド（DOT） | 2849 153 |
| 反応性グループ | Alcohols and Polyols |
| Reactivity Profile | 3-CHLOROPROPANOL-1 may be sensitive to prolonged exposure to light. This compound may react with oxidizing agents. (NTP, 1992). |
| DOT Hazard Classification | 3-Chloropropanol-1UN2849Div 6.1 Poisonous materials (49 eCFR § 173.132)PG III: the degree of danger presented by the material is minor |
| Air and Water Reactions | Moderately soluble in water. |
| Hazard Classes and Categories | Acute Tox. 4 (22.9%)Flammable agents - 2nd degree |
| 消火 | Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: |
| 漏出応急措置 | · CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. |
| 応急処置 | EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.General First Aid: |
| 暴露管理・個人防護 | · Wear positive pressure self-contained breathing apparatus (SCBA). |
| 非火災時の漏出対応 | Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: |
| Isolation and Evacuation | Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:Immediate precautionary measure |
| Protective Action Criteria (PAC) | 6.0 [mg/m3]41 [mg/m3]250 [mg/m3] |
| Personal Protective Equipment (PPE) | Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: |
| Emergency Response Planning Guidelines | Small Fire |
| 有害作用 | Neurotoxin - Acute solvent syndrome |
用途
一般的な説明
A colorless liquid with a mild odor. Boils at 261.5°F. Flash point 125°F. Density 1.11 g / cm3. Toxic upon prolonged exposure to low concentrations of the vapor or to short exposure to high concentrations of the vapor by inhalation. Used in the manufacture of various organic chemicals.