化工社化工社 化学情報印刷レポート · 研究参考用
2-mercaptomethyl-3-guanidinoethylthiopropionic acid
2-mercaptomethyl-3-guanidinoethylthiopropionic acid · Propanoic acid, 3-[[2-[(aminoiminomethyl)amino]ethyl]thio]-2-(mercaptomethyl)-
識別子と物理属性
| CAS No. | 77102-28-4 |
|---|---|
| 分子式 | C7H15N3O2S2 |
| 平均分子量 | 237.34 g/mol |
| SMILES | NC(N)=NCCSCC(CS)C(=O)O |
| InChIKey | AKPKWZRKZOAAAZ-UHFFFAOYSA-N |
| PubChem CID | 123726 |
化学・物理的性質
| 沸点 | 427.0±55.0 °C(Predicted) |
|---|---|
| 密度 | 1.47±0.1 g/cm3(Predicted) |
| 溶解度 | DMSO (Slightly, Heated), Methanol (Very Slightly, Heated), Water (Slightly, Sonicated) |
| pKa（酸解離定数） | 3.97±0.11(Predicted) |
| 外観・状態 | Solid |
| 色 | White to Off-White |
| 安定性 | Air Sensitive, Hygroscopic |
用途
使用
Mergetpa is a potent mercapto bi-product analogue inhibitor for human carboxypeptidase N. Carboxypeptidase N is a potent bradykinin and anaphylatoxin inactivator in plasma. Mergetpa improves rt-PA induced thrombolysis in a dog model of coronary artery thrombosis.