712-48-1Cl[As](c1ccccc1)c1ccccc1YHHKGKCOLGRKKB-UHFFFAOYSA-NDiphenylchloroarsine appears as a chemical warfare vomiting agent. It is a colorless crystalline solid, or a dark-brown liquid. Strongly irritating to skin and eyes. Toxic by ingestion and inhalation.
Relative density (water = 1): 1.4 (45 °C)
1.333 @ 40°C
38-44 °C
44 °C
Vapor pressure, Pa at 20 °C: 0.06
0.00049 [mm Hg] @20 °C
Diphenylchloroarsine appears as a chemical warfare vomiting agent. It is a colorless crystalline solid, or a dark-brown liquid. Strongly irritating to skin and eyes. Toxic by ingestion and inhalation.
COLOURLESS CRYSTALS. TECHNICAL-GRADE PRODUCT: DARK BROWN LIQUID.
Restricted substance: Chlorodiphenylarsine
The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)
For information on chemical warfare vomiting agents see the ERG Criminal or Terrorist Use of CBR Agents. (ERG, 2024)
· Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
· Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
For information on chemical warfare vomiting agents see the ERG Criminal or Terrorist Use of CBR Agents. (ERG, 2024)
· Highly toxic, may be fatal if inhaled, ingested or absorbed through skin.
· Highly toxic, may be fatal if inhaled, ingested or absorbed through skin.
3450 151
1699 151
DIPHENYLCHLOROARSINE is incompatible with strong oxidizing agents, amines, and alkalis. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].
Arsenic is absorbed mainly by inhalation or ingestion, as to a lesser extent, dermal exposure. It is then distributed throughout the body, where it is reduced into arsenite if necessary, then methylated into monomethylarsenic (MMA) and dimethylarsenic acid (DMA) by arsenite methyltransferase. Arsenic and its metabolites are primarily excreted in the urine. Arsenic is known to induce the metal-binding protein metallothionein, which decreases the toxic effects of arsenic and other metals by binding them and making them biologically inactive, as well as acting as an antioxidant. (L20)
解説C12H10ClAs(264.6).(C6H5)2AsCl.クロロジフェニルアルシン,テトラフェニル鉛と三塩化ヒ素を加熱すると得られる.融点38 ℃,沸点333 ℃.d1441.423.眼,鼻,のどなどの粘膜をはげしく刺激する中毒性の有毒ガス.LD50 28.07 mg/kg(ラット,経口).森北出版「化学辞典(第2版)
一般的な説明A colorless crystalline solid, or a dark-brown liquid. Strongly irritating to skin and eyes. Toxic by ingestion and inhalation. Used as a military poison gas.
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読み込み中…
712-48-1DTXSID30858733For information on chemical warfare vomiting agents see the ERG Criminal or Terrorist Use of CBR Agents. (ERG, 2024)
In case of fire in the surroundings, use appropriate extinguishing media. In case of fire: keep drums, etc., cool by spraying with water.
Fresh air, rest. Half-upright position. Refer for medical attention.
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Refer for medical attention .
· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.
· Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.
· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.
· Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.
For information on chemical warfare vomiting agents see the ERG Criminal or Terrorist Use of CBR Agents. (ERG, 2024)
General First Aid:
General First Aid:
· Wear positive pressure self-contained breathing apparatus (SCBA).
· Wear positive pressure self-contained breathing apparatus (SCBA).
Sweep spilled substance into covered containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment. Personal protection: chemical protection suit including self-contained breathing apparatus.
For initial isolation and protective action distances for chemical warfare vomiting agents see the Chemical Warfare Agents table in the ERG Criminal or Terrorist Use of CBR Agents. (ERG, 2024)
Immediate precautionary measure
Immediate precautionary measure
Arsenic poisoning can be treated by chelation therapy, using chelating agents such as dimercaprol, EDTA or DMSA. Charcoal tablets may also be used for less severe cases. In addition, maintaining a diet high in sulfur helps eliminate arsenic from the body. (L20)
The substance can be absorbed into the body by inhalation of its aerosol.
Oral (L2) ; inhalation (L2) ; dermal (L2)
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by competing with phosphate it uncouples oxidative phosphorylation, thus inhibiting energy-linked reduction of NAD+, mitochondrial respiration, and ATP synthesis. Hydrogen peroxide production is also increased, which might form reactive oxygen species and oxidative stress. Arsenic's carginogenicity is influenced by the arsenical binding of tubulin, which results in aneuploidy, polyploidy and mitotic arrests. The binding of other arsenic protein targets may also cause altered DNA repair enzyme activity, altered DNA methylation patterns and cell proliferation. (T1, A17)
Sore throat. Cough. Headache. Nausea. Vomiting. Laboured breathing. Shortness of breath. Chest tightness. Unconsciousness. Symptoms may be delayed.
Redness.
Watering of the eyes. Redness.
Abdominal pain. Headache. Nausea. Vomiting.
Exposure to lower levels of arsenic can cause nausea and vomiting, decreased production of red and white blood cells, abnormal heart rhythm, damage to blood vessels, and a sensation of