グリシジルメチルエーテル

1,2-Epoxy-3-methoxypropane

HCID 13589CAS 930-37-0

基本情報

標準SMILES
COCC1CO1
InChIKey
LKMJVFRMDSNFRT-UHFFFAOYSA-N
分子式
C4H8O2
平均分子量
88.11 g/mol
単同位体質量
88.0524295

概要

Methyl glycidyl ether is a clear colorless liquid. (NTP, 1992)

名称と識別子

優先名称
1,2-Epoxy-3-methoxypropane
IUPAC
2-(methoxymethyl)oxirane
現地名
グリシジルメチルエーテル
英語名
GLYCIDYL METHYL ETHER
分子式
C4H8O2
分子量
88.11

名称と別名

Glycidyl methyl ether930-37-0Methyl glycidyl etherOxirane, (methoxymethyl)-1,2-EPOXY-3-METHOXYPROPANEGlycidol methyl ether(Methoxymethyl)oxiraneMethylglycidyl ether3-Methoxypropylene oxide3-Methoxy-1,2-epoxypropanePropane, 1,2-epoxy-3-methoxy-2,3-Epoxypropyl-methyl ether
名称をさらに表示
グリシジルメチルエーテルメチル(グリシジル)エーテルメチルグリシジルエーテル1,2-エポキシ-3-メトキシプロパン1-メトキシ-2,3-エポキシプロパン(オキシラニルメチル)メチルエーテル2-メトキシメチルオキシラン2-(メトキシメチル)オキシラングリシドールメチルエーテル(メトキシメチル)オキシランオキシラニルメチル(メチル)エーテル2-(Methoxymethyl)oxiraneoxirane,(methoxymethyl)-Epiol MEpimethylinDenacol EX-131glycidolmethylethermethylglycidylether
Oxirane, 2-(methoxymethyl)-NSC 86950CCRIS 2630HSDB 5444EINECS 213-216-7BRN 010250587MK2KA66TAI3-52869

データベース識別子

CAS
930-37-0
PubChem CID
13589
DTXSID
DTXSID9025613
UNII
87MK2KA66T
EC Number
213-216-7
Nikkaji
J60.714B

物性

構造計算による物性

XLogP
-0.2
極性表面積
21.8 Ų
水素結合供与体数
0
水素結合受容体数
2
回転可能結合数
2
重原子数
6

実験および物理化学的性質

PolymersPlastics & Rubber -> Glycidyl Ethers
LogP0.03
Solubilitygreater than or equal to 100 mg/mL at 68.9 °F (NTP, 1992)
Flash Point · 2 件

less than 69 °F (NTP, 1992)

Flash point < 21 °C

Physical Description · 2 件

Methyl glycidyl ether is a clear colorless liquid. (NTP, 1992)

Colorless liquid; [CAMEO]

物理化学的性質

沸点
110 °C · 110°C
比重(密度)
0 · 0,98 g/cm3
屈折率
1.408 · 1.4080-1.4140
闪点
24 °C · 24°C
貯蔵温度
Refrigerator
溶解性
クロロホルム(微量)、トルエン(微量)

安全と法規制

GHS分類

GHS Classification · 6 件

Danger

H225 (75%): Highly Flammable liquid and vapor [Danger Flammable liquids]

P210, P233, P240, P241, P242, P243, P261, P262, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P316, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 4 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

H225: Highly Flammable liquid and vapor [Danger Flammable liquids]

危険有害性情報

DOT LabelFlammable Liquid Poison
Fire HazardsThis chemical is flammable. (NTP, 1992)
Health HazardsExcerpt from ERG Guide 131 [Flammable Liquids - Toxic]:
Hazards SummaryA mutagen and primary irritant; Caused lacrimation and somnolence in lethal-dose feeding studies of rats; [RTECS] Emergency treatment: irritants; [HSDB] An irritant; [MSDSonline]
Reactive GroupEthers
Reactivity AlertsHighly Flammable

安全と保護具

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1 件

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 件

SMALL SPILLS AND LEAKAGE: If you should spill this chemical, use absorbent paper to pick up all liquid spill material. Seal the absorbent paper, as well as any of your clothing which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Wash any surfaces you may have contaminated with a strong soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Isolation and EvacuationExcerpt from ERG Guide 131 [Flammable Liquids - Toxic]:
Personal Protective Equipment (PPE) · 1 件

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

毒性情報

Non-Human Toxicity Excerpts · 3 件

...THEY ARE VERY IRRITATING TO EYES, SKIN, & RESPIRATORY TRACT. /GLYCIDYL ETHERS/

1,2-EPOXY-3-METHOXYPROPANE WAS MUTAGENIC IN KLEBSIELLA PNEUMONIAE.

TOPICAL APPLICATION OF 0.1 ML ALIQUOT OF 1,2-EPOXY-3-METHOXYPROPANE TO CLIPPED & DEPILATED BACKS OF GUINEA PIGS 4 TIMES IN 10 DAYS. AFTER 2 WK REST PERIOD, GUINEA PIGS WERE CHALLENGED ON THE CLIPPED FLANKS. TWO OF THE 49 GUINEA PIGS TESTED BECAME SENSITIZED.

安全データ

tsca
TSCA listed
rtecs
TZ3530000
ridadr
3271
hs_code
2909200090
risk_code
10
化審法
(2)-2425

化学と産業

用途と製造

Uses · 2 件

Used as a research chemical; Not commercially produced in the US; [HSDB]

RESEARCH CHEMICAL

U.S. Exports · 2 件

(1979) No Data

(1981) No Data

U.S. Imports · 2 件

(1979) No Data

(1981) No Data

U.S. Production · 2 件

(1979) NOT PRODUCED COMMERCIALLY IN U.S.

(1981) NOT PRODUCED COMMERCIALLY IN U.S.

Methods of ManufacturingPROBABLY BY REACTION OF 1-CHLORO-2-HYDROXY-3-METHOXYPROPANE WITH SODIUM HYDROXIDE
General Manufacturing InformationOxirane, 2-(methoxymethyl)-: ACTIVE

応用分野

使用2-(Methoxymethyl)oxirane is used in the fixation of biological tissues or in collagen bioprosthetic fixation processes.

一般的な説明Clear colorless liquid.

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関連反応

27 件

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