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ニューフクシン

New Fuchsin

HCID 14454445
ノート反応
基本情報概要名称と識別子物性安全と法規制化学と産業関連反応化合物ノート
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基本情報

CAS
3248-91-7
標準SMILES
CC1=CC(=C(c2ccc(N)c(C)c2)c2ccc(N)c(C)c2)C=CC1=N.Cl
InChIKey
IPSIPYMEZZPCPY-UHFFFAOYSA-N
分子式
C22H23N3.ClH
平均分子量
365.9 g/mol
単同位体質量
365.1658755

概要

New fuchsin is a hydrochloride that is the monohydrochloride of 4-[(4-aminophenyl)(4-iminocyclohexa-2,5-dien-1-ylidene)methyl]-2-methylaniline. One of the minor constituents of Basic fuchsin, together with pararosanilin, rosanilin and magenta II. It has a role as a fluorochrome and a histological dye. It contains a new fuchsin(1+).

名称と識別子

優先名称
New Fuchsin
IUPAC
4-[(4-amino-3-methylphenyl)-(4-imino-3-methylcyclohexa-2,5-dien-1-ylidene)methyl]-2-methylaniline;hydrochloride
現地名
ニューフクシン
英語名
Basic Violet 2
分子式
C22H24ClN3
分子量
365.91

名称と別名

New fuchsinBASIC VIOLET 23248-91-7Magenta IIINeofuchsineNew magentaRemacryl magenta BAstrazon fuchsine GNTrimethyl fuchsinC.I. Basic Violet 2Fuchsin NBNSC-9858
名称をさらに表示
ニューフクシン4-[(4-アミノ-3-メチルフェニル)(4-イミノ-3-メチル-2,5-シクロヘキサジエン-1-イリデン)メチル]-2-メチルベンゼンアミン·塩酸塩マゼンタIIIC.I.ベーシックバイオレット2C.I.ベーシックバイオレット24ニューマゼンタニューフクシン(塩基性)ニューフクシン [生化学用]ベーシックバイオレット2塩基性紫24-[(4-アミノ-3-メチルフェニル)(4-イミノ-3-メチル-2,5-シクロヘキサジエン-1-イリデン)メチル]-2-メチルベンゼンアミン・塩酸塩newFUCHSINIsorubinfuchsinnbisorubineFUCHSIN N
CI 42520C.I. 42520CHEBI:87671DTXSID80879817A051F48W36Benzenamine, 4,4'-((4-imino-3-methyl-2,5-cyclohexadien-1-ylidene)methylene)bis(2-methyl-, monohydrochlorideRefChem:572236DTXCID701017817

データベース識別子

CAS
3248-91-7
PubChem CID
14454445
DTXSID
DTXSID80879817
ChEMBL
CHEMBL1979779
ChEBI
CHEBI:87671
UNII
A051F48W36
EC Number
221-831-7、682-577-4

物性

構造計算による物性

極性表面積
75.9 Ų
水素結合供与体数
4
水素結合受容体数
3
回転可能結合数
2
重原子数
26
形式電荷
0
複雑度
585

実験および物理化学的性質

CosmeticsCosmetic colorant
Endocrine DisruptorsPotential endocrine disrupting compound

物理化学的性質

沸点
300 ℃[at · 300℃[at 101 325 Pa]
比重(密度)
0.692 · 0.692[at 20℃]
蒸気圧
0 Pa · 0Pa at 25℃
貯蔵温度
5 °C · Store at +5°C to +30°C.
溶解性
10 g/リットル · 10g/リットル
外見
結晶または結晶性粉末
色
濃い緑色
PH
3 · 3-4 (10g/l, H2O, 20℃)
水溶解度
20 g/L · 20g/L
BRN
8740867 · 8740867
安定性
安定。強力な酸化剤とは相容れない。
主な用途
診断アッセイの製造血液学組織学
化粧品成分の機能
ヘアカラーリング着色剤
InChI
1S/C22H24N3.ClH/c1-13-10-16(4-7-19(13)23)22(17-5-8-20(24)14(2)11-17)18-6-9-21(25)15(3)12-18;/h4-12H,23-25H2,1-3H3;1H/q+1;/p-1
InChIKey
ORDGVBRMUJCHEO-UHFFFAOYSA-M
LogP
1.537 · 1.537
CAS データベース
3248 · 3248-91-7(CAS DataBase Reference)
EPAの化学物質情報
4 · Benzenamine, 4,4'-[(4-imino-3-methyl-2,5-cyclohexadien-1-ylidene)methylene]bis[2-methyl-, hydrochloride (1:1) (3248-91-7)

化学的性質

化学的特性solid

安全と法規制

安全情報は参考情報です。供給元の安全データシート(SDS)、適用法令、専門家による評価に代わるものではありません。

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 1.6% (2 of 123) of reports.

Danger

H315 (45.5%): Causes skin irritation [Warning Skin corrosion/irritation]

P203, P260, P261, P264, P264+P265, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P318, P319, P321, P332+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 123 reports by companies from 21 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Not Classified

危険有害性情報

Regulatory Information · 3 件

Chemical: Benzenamine, 4-[(4-amino-3-methylphenyl)(4-imino-3-methyl-2,5-cyclohexadien-1-ylidene)methyl]-2-methyl-, monohydrochloride

REACH registered substance: 4-[(4-amino-m-tolyl)(4-imino-3-methylcyclohexa-2,5-dien-1-ylidene)methyl]-o-toluidine monohydrochloride (EC: 221-831-7)

New fuchsin: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and Categories · 3 件

Skin Irrit. 2 (45.5%)

Not Classified

Carcinogenicity - Category 2

安全データ

wgk
3
tsca
TSCA listed
rtecs
CX9825000
ridadr
UN 3077 9 / PGIII
hs_code
32041300
risk_code
36/37/38-40-36-50/53
化審法
(5)-1970
hazard_code
Xn,Xi,N,T
safety_code
26-36/37-24/25-61-60
Hazard Classifications
Aquatic Acute 1Aquatic Chronic 1Carc. 1BEye Irrit. 2Skin Irrit. 2STOT SE 3
ストレージクラス
6.1C - Combustible, acute toxic Cat.3toxic compounds or compounds which causing chronic effects

化学と産業

用途と製造

Use ClassificationCosmetics -> Cosmetic colorant
General Manufacturing InformationBenzenamine, 4,4'-[(4-imino-3-methyl-2,5-cyclohexadien-1-ylidene)methylene]bis[2-methyl-, hydrochloride (1:1): ACTIVE
応用分野 · 2 件

使用Textiles and leather industries, red dye, pharmaceutical.

一般的な説明The dry dye New fuchsin (C.I. 42520) for microscopy Certistain, is used for the preparation of a staining solution that can be used for staining of histological tissue sections or other samples of human origin according to Ziehl-Neelsen, Gram staining as well as in combination with Schiff′s reagent. As a Certistain dye it is chemically quality-certified according to highest standards and strict specifications. New fuchsin belongs to the group of triaminotriphenylmethane dyes.The dye is used in Ziehl-Neelsen and Gram staining as well as for methods with Schiff′s reagent.The cell wall of acid-fast bacteria (AFB) has a high proportion of wax and lipids and hence absorbs dyes only very slowly. As a measure to enhance the absorption of the fuchsin dye and thus the formation of the mycolate-fuchsin complex in the cell wall, the carbolfuchsin solution applied to the specimen is normally heated to evaporation point. If the Kinyoun carbolfuchsin solution is used, the heating of the solution is dispensable. Consequently, the release of hazardous phenolic vapors will be avoided.Once the AFB have absorbed the fuchsin dye, it is virtually impossible to decolorize them again, even when they are intensively treated with a decolorizing solution such as e. g. hydrochloric acid in ethanol. Accordingly, AFB are termed as acid- and alcohol-fast for staining, and are stained red in the microscopic visualization. Correspondingly, all non-acid-fast microorganisms are counterstained with an appropriate dye.Pretreatment of the specimens with Sputofluol dissolves the bacteria from the surrounding viscid sputum and cell material. Sputofluol also has a disinfectant effect, with the result that any microorganisms that are present are killed off. It is registered as IVD and certified as CE product. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.

調製方法

製造方法Commonly known as the New Magenta. 4 – (4-Amino-3-methylbenzyl)-2-methylbenzenamine with O-Methylaniline its hydrochloride salt is heated in the presence of an oxidizing agent.

上流・下流製品情報

上流原料

4,4'-ジアミノ-3,3'-ジメチルジフェニルメタンo-トルイジン

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補足説明

定義本品は、次の化学式で表されるトリフェニルメタン系色素である。

定義ChEBI: A hydrochloride that is the monohydrochloride of 4-[(4-aminophenyl)(4-iminocyclohexa-2,5-dien-1-ylidene)methyl]-2-methylaniline. One of the minor constituents of Basic fuchsin, together with pararosanilin, rosanilin and magenta II.

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