Monolaurin (HCID 14871)

概要

1-monolauroylglycerol is a 1-monoglyceride with dodecanoyl (lauroyl) as the acyl group. It is a 1-monoglyceride and a dodecanoate ester.

名称と識別子

優先名称: Monolaurin
IUPAC: 2,3-dihydroxypropyl dodecanoate
英語名: Glycery Monolaurate
分子量: 0

名称と別名

MonolaurinGlycerol monolaurateGLYCERYL LAURATE27215-38-9MonolauroylglycerinGlycerox L 8Cithrol GMLDodecanoic acid, monoester with 1,2,3-propanetriolLaurin, mono-Aldo MLDMonoglycerol laurateGrindtek ML 90

名称をさらに表示

Monomuls L 90Dimodan ML 90Imwitor 312Sunsoft 750Sunsoft 757Monomuls 90L12Monododecanoyl glycerolTegin L 90

データベース識別子

CAS: 142-18-7、27215-38-9、40738-26-9、67701-26-2
PubChem CID: 14871
DTXSID: DTXSID5041275
ChEMBL: CHEMBL510533
ChEBI: CHEBI:75539
UNII: WR963Y5QYW
EC Number: 205-526-6、248-337-4
Nikkaji: J53.671G

物性

構造計算による物性

XLogP: 4.2
極性表面積: 66.8 Å²
水素結合供与体数: 2
水素結合受容体数: 4
回転可能結合数: 14
重原子数: 19
形式電荷: 0
複雑度: 206

実験および物理化学的性質

Cosmetics · 2 件

Cosmetic ingredients (Glyceryl Laurate) -> CIR (Cosmetic Ingredient Review)

Emulsifying; Emollient

FragrancesFragrance Ingredient (Dodecanoic acid, 2,3-dihydroxypropyl ester) -> IFRA transparency List

Physical DescriptionLarge Crystals; Liquid

Collision Cross Section176.3 Å² [M+Na]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID5041275]

安全と法規制

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 64.1% (159 of 248) of all reports.

Warning

H319 (35.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement)

Aggregated GHS information provided per 248 reports by companies from 2 notifications to the ECHA C&L Inventory.

This chemical does not meet GHS hazard criteria for 100% (5 of 5) of all reports.

危険有害性情報

Regulatory Information · 6 件

Chemical: Dodecanoic acid, 2,3-dihydroxypropyl ester

Chemical: Dodecanoic acid, monoester with 1,2,3-propanetriol

Dodecanoic acid, 2,3-dihydroxypropyl ester is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Dodecanoic acid, 2,3-dihydroxypropyl ester are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 24-08-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/13112

Dodecanoic acid, 2,3-dihydroxypropyl ester: Does not have an individual approval but may be used under an appropriate group standard

Dodecanoic acid, monoester with 1,2,3-propanetriol: Does not have an individual approval but may be used under an appropriate group standard

Other Safety Information · 2 件

IMAP assessments - Dodecanoic acid, 2,3-dihydroxypropyl ester: Human health tier I assessment

IMAP assessments - Dodecanoic acid, monoester with 1,2,3-propanetriol: Human health tier I assessment

EPA Safer ChemicalChemical: Glyceryl monolaurate

Hazard Classes and Categories · 2 件

Eye Irrit. 2 (35.9%)

Not Classified

毒性情報

Toxicity SummarySafe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org

化学と産業

薬理情報

MeSH Pharmacological Classification · 2 件

Substances that inhibit or arrest DENTAL CARIES formation. (Boucher's Clinical Dental Terminology, 4th ed)

Agents that modify interfacial tension of water; usually substances that have one lipophilic and one hydrophilic group in the molecule; includes soaps, detergents, emulsifiers, dispersing and wetting agents, and several groups of antiseptics.