2-クロロエタンスルホニルクロリド

Ethanesulfonylchloride, 2-chloro-

HCID 15385

基本情報

CAS
1622-32-8
標準SMILES
O=S(=O)(Cl)CCCl
InChIKey
VHCSBTPOPKFYIU-UHFFFAOYSA-N
分子式
C2H4Cl2O2S
平均分子量
163.02 g/mol
単同位体質量
161.93090573

概要

Ethanesulfonyl chloride, 2-chloro- appears as a liquid. Density 1.56 g / cm3. Flash point exceeds 230 °F.

名称と識別子

優先名称
Ethanesulfonylchloride, 2-chloro-
IUPAC
2-chloroethanesulfonyl chloride
現地名
2-クロロエタンスルホニルクロリド
英語名
2-chloroethanesulfonyl chloride
分子式
C2H4Cl2O2S
分子量
163.02

名称と別名

2-Chloroethanesulfonyl chloride1622-32-8Ethanesulfonyl chloride, 2-chloro-(2-Chloroethyl)sulphonyl chloride2-Chloroethylsulfonyl chloride2-Chloroethane sulfochloridebeta-Chloroethanesulfonyl chloride2-chloro-1-ethanesulfonyl chlorideHSDB 6420ETHANESULFONYLCHLORIDE, 2-CHLORO-AET6VQ5A3Qchloroethanesulfonyl chloride
名称をさらに表示
2-クロロエタンスルホニルクロリド2-クロロエタンスルホン酸クロリド2-クロロ-1-エタンスルホニルクロリド2-クロロエタン-1-スルホン酸クロリド塩化2-クロルエタンスルホニル2-クロロエタンスルホニルクロライド 塩化物2‐クロロエタンスルホニルクロリド2-クロロエタンスルホニルクロリド, 98%2-クロロエタンスルホニルクロライド2-クロロエタン-1-スルホニル クロリド塩化2-クロロエタンスルホニル(2-クロロエチル)クロロスルホンoroethanesuL2-chloroethanesulfochloride2-chloroethylsulfonylchloride2-chloro-ethanesulfonylchlorid2-chloroethanesulfochloride[qr]2-CHLOROETHANESULPHONYL CHLORIDEbeta-chloroethanesulfonylchloride2-chloroethylsulfonylchloride[qr]
EINECS 216-594-1BRN 1751202DTXSID50618254-04-00-00036 (Beilstein Handbook Reference)2-chloroethanesulfonic acid chlorideRefChem:5918272Chloroethane sulfochloride2Chloroethylsulfonyl chloride

データベース識別子

CAS
1622-32-8
PubChem CID
15385
DTXSID
DTXSID5061825
UNII
AET6VQ5A3Q
EC Number
216-594-1
Nikkaji
J78.119C

物性

構造計算による物性

XLogP
1
極性表面積
42.5 Ų
水素結合供与体数
0
水素結合受容体数
2
回転可能結合数
2
重原子数
7

実験および物理化学的性質

Chemical Classes · 2 件

Toxic Gases & Vapors -> Acid Halides

Reactive agents - 1st degree

SpringerMaterials PropertiesNuclear quadrupole resonance spectroscopy
Density · 3 件

1.55 at 68 °F (EPA, 1998) - Denser than water; will sink

1.555 at 20 °C/4 °C

1.555 @ 20°C

Boiling Point · 2 件

392 to 397 °F at 760 mmHg (EPA, 1998)

200-3 °C

Physical Description · 2 件

Ethanesulfonyl chloride, 2-chloro- appears as a liquid. Density 1.56 g / cm3. Flash point exceeds 230 °F.

Liquid; [CAMEO] Colorless liquid; [MSDSonline]

物理化学的性質

融点
3 °C · 3 °C
沸点
84 · 84-86 °C15 mm Hg(lit.)
比重(密度)
1.56 g/mL · 1.56 g/mL at 25 °C(lit.)
蒸気圧
15 mm · 15 mm Hg ( 84 °C)
屈折率
20 · n20/D 1.493(lit.)
闪点
230 °F · >230 °F

化学的性質

化学的特性CLEAR SLIGHTLY YELLOW TO BROWN LIQUID

安全と法規制

GHS分類

GHS Classification · 6 件

Danger

H301 (97.9%): Toxic if swallowed [Danger Acute toxicity, oral]

P260, P264, P270, P271, P280, P284, P301+P316, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P320, P321, P330, P363, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 47 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

H301: Toxic if swallowed [Danger Acute toxicity, oral]

危険有害性情報

Regulatory InformationThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)
DOT LabelPoison Inhalation Hazard Dangerous When Wet
Fire HazardsExcerpt from ERG Guide 139 [Substances - Water-Reactive (Emitting Flammable and Toxic Gases)]:
Health HazardsExcerpt from ERG Guide 139 [Substances - Water-Reactive (Emitting Flammable and Toxic Gases)]:
Hazards Summary · 1 件

Reacts with water evolving hydrogen chloride; [CAMEO] Reacts violently with water; A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis; Effects in high-dose animal studies include abnormal liver function tests; [MSDSonline] See Ethanesulfonyl chloride.

Reactive GroupHalogenated Organic Compounds

安全と保護具

Fire FightingExcerpt from ERG Guide 139 [Substances - Water-Reactive (Emitting Flammable and Toxic Gases)]:
First Aid · 1 件

Signs and Symptoms of Ethanesulfonyl Chloride, 2-Chloro- Exposure: No information is available on specific clinical effects of exposure to ethanesulfonyl chloride, 2-chloro- exposure. However, because ethanesulfonyl chloride, 2-chloro- is expected to be an irritant and general toxicant, signs and symptoms of exposure may include the following: headache, dizziness, weakness, nausea, irritation of the eyes, skin, and respiratory tract, and dermatitis. Severe respiratory tract irritation can progress to pulmonary edema, the onset of which may be delayed 24-72 hours. Irritation or burns of the esophagus or gastrointestinal tract are possible.

Nonfire Spill ResponseExcerpt from ERG Guide 139 [Substances - Water-Reactive (Emitting Flammable and Toxic Gases)]:
Disposal Methods · 1 件

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Isolation and EvacuationExcerpt from ERG Guide 139 [Substances - Water-Reactive (Emitting Flammable and Toxic Gases)]:
Protective Action Criteria (PAC) · 3 件

0.23 [mg/m3]

2.5 [mg/m3]

19 [mg/m3]

毒性情報

Adverse EffectsOccupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.
Toxicity DataLC50 (rat) = 420 mg/m3/4h

安全データ

F
10-19
wgk
3
tsca
TSCA listed
rtecs
KI8060000
ridadr
UN 3390 6.1/PG 1
毒性
mouse,LC50,inhalation,250mg/m3/4H (250mg/m3),Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 15(6), Pg. 59, 1971.

化学と産業

用途と製造

General Manufacturing InformationEthanesulfonyl chloride, 2-chloro-: ACTIVE
応用分野 · 2 件

使用2-Chloroethanesulfonyl chloride was used in one-pot sulfonylation/intramolecular thia-Michael protocol for the synthesis of 1,5,2-dithiazepine 1,1-dioxides. It was also used in synthesis of vinyl sulfonamides with a furan, carbocyclic, semi cyclic or acyclic 1,3-diene moiety.

一般的な説明A liquid. Density 1.56 g / cm3. Flash point exceeds 230°F.

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