NAAD+
ニコチン酸アデニンジヌクレオチド · 1-[(2R,3R,4S,5R)-5-[({[({[(2R,3S,4R,5R)-5-(6-アミノ-9H-プリン-9-イル)-3,4-ジヒドロキシオキソラン-2-イル]メトキシ}(ヒドロキシ)ホスホリル)オキシ](ヒドロキシ)ホスホリル}オキシ)メチル]-3,4-ジヒドロキシオキソラン-2-イル]-1λ5-ピリジン-1-イリウム-3-カルボキシラート · デアミド-NAD · NAAD+ · 3-カルボキシラト-1-[5-O-[(5′-アデニリルオキシ)ホスホニル]-β-D-リボフラノシル]ピリジニウム · 1-[5-[[[[5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxymethyl]-3,4-dihydroxy-oxolan-2-yl]pyridine-5-carboxylate · ONAD · NAAD(O-NAD)
識別子と物理属性
| CAS No. | 6450-77-7 |
|---|---|
| 分子式 | C21H26N6O15P2 |
| 平均分子量 | 664.414 g/mol |
| 単同位体質量 | 664.09313739 g/mol |
| SMILES | Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OC[C@H]2O[C@@H]([n+]3cccc(C(=O)[O-])c3)[C@H](O)[C@@H]2O)[C@@H](O)[C@H]1O |
| InChIKey | SENPVEZBRZQVST-HISDBWNOSA-N |
| PubChem CID | 165490 |
| DTXSID | DTXSID30863847 |
| 現地名 | NAAD+ |
化学・物理的性質
| InChIKey | SENPVEZBRZQVST-KQGQPLBUNA-N |
|---|---|
| SMILES | O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@H]([N+]3=CC=CC(C(=O)[O-])=C3)O2)O)O[C@H]1N1C=NC2=C(N=CN=C12)N)O |&1:1,2,3,15,16,17,19,32,r| |
用途
使用
Nicotinic Acid Adenine Dinucleotide is an analog of β-Nicotinamide Adenine Dinucleotide (N407775, Hydrate); a coenzyme consisting of an adenine base and a nicotinamide base connected by a pair of bridging phosphate groups. β-Nicotinamide Adenine Dinucleotide acts as a coenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide Adenine Dinucleotide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins.