化工社化工社 化学情報印刷レポート · 研究参考用
o-メチルフェニルグリシジルエーテル
グリシジル(o-トリル)エーテル · 2-(2-メチルフェノキシメチル)オキシラン · 1-(オキシラニルメトキシ)-2-メチルベンゼン · (2-メチルフェニル)グリシジルエーテル · グリシジル(2-メチルフェニル)エーテル · 2-メチルフェニルグリシジルエーテル · [(2-メチルフェノキシ)メチル]オキシラン · 2-[(2-メチルフェノキシ)メチル]オキシラン
識別子と物理属性
| CAS No. | 2210-79-9 |
|---|---|
| 分子式 | C10H12O2 |
| 平均分子量 | 164.2 g/mol |
| 単同位体質量 | 164.08372962 g/mol |
| SMILES | Cc1ccccc1OCC1CO1 |
| InChIKey | KFUSXMDYOPXKKT-UHFFFAOYSA-N |
| PubChem CID | 16640 |
| ChEMBL | CHEMBL1445408 |
| EC No. | 218-645-3 |
| DTXSID | DTXSID8024862 |
| 現地名 | o-メチルフェニルグリシジルエーテル |
化学・物理的性質
| XLogP | 2.4 |
|---|---|
| 極性表面積 | 21.8 |
| 水素結合供与体数 | 0 |
| 水素結合受容体数 | 2 |
| 回転可能結合数 | 3 |
| 重原子数 | 12 |
| 形式電荷 | 0 |
| 複雑度 | 147 |
| Polymers | Plastics & Rubber -> Glycidyl Ethers |
| 密度 | 1.09 at 68 °F (NTP, 1992) - Denser than waterwill sinkRelative density (water = 1): 1.081.079 g/mL at 25 °C (lit.) |
| 溶解度 | less than 1 mg/mL at 72 °F (NTP, 1992)Solubility in water: none840mg/L at 21℃ |
| 引火点 | 200 °F (NTP, 1992)113 °C c.c.>230 °F |
| 沸点 | 498 °F at 760 mmHg (NTP, 1992)at 0.533kPa: 109-111 °C109-111 °C/4 mmHg (lit.) |
| 蒸気密度 | Relative vapor density (air = 1): 5.7>1 (vs air) |
| Physical Description | O-cresyl glycidyl ether is a clear light yellow liquid. (NTP, 1992)Clear light yellow liquid[CAMEO]COLOURLESS LIQUID. |
| 蒸気圧 | 0.514Pa at 20℃ |
| 屈折率 | n20/D 1.529(lit.) |
| 外観・状態 | liquid |
| BRN | 4585 |
| InChI | InChI=1S/C10H12O2/c1-8-4-2-3-5-10(8)12-7-9-6-11-9/h2-5,9H,6-7H2,1H3 |
| InChIKey | KFUSXMDYOPXKKT-UHFFFAOYSA-N |
| SMILES | O1CC1COC1=CC=CC=C1C |
| LogP（分配係数） | 2.5 at 21℃ |
| CAS データベース | 2210-79-9(CAS DataBase Reference) |
| NISTの化学物質情報 | Oxirane, [(2-methylphenoxy)methyl]-(2210-79-9) |
| EPAの化学物質情報 | o-Cresyl glycidyl ether (2210-79-9) |
安全性と法規制
| GHS 分類 | WarningH315: Causes skin irritation [Warning Skin corrosion/irritation]P203, P261, P264, P272, P273, P280, P302+P352, P318, P321, P332+P317, P333+P317, P362+P364, P391, P405, and P501 (click each P-code to see the statement)H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
|---|---|
| 規制情報 | Chemical: Oxirane, [(2-methylphenoxy)methyl]-Oxirane, 2-[(2-methylphenoxy)methyl]- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Oxirane, 2-[(2-methylphenoxy)methyl]- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)TP - indicates a substance that is the subject of a proposed TSCA section 4 test rule.Status: Active Update: 05-04-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/14553Oxirane, [(2-methylphenoxy)methyl]-: Does not have an individual approval but may be used under an appropriate group standard |
| その他の安全情報 | IMAP assessments - Oxirane, [(2-methylphenoxy)methyl]-: Environment tier I assessment |
| 輸送ラベル（DOT） | Class 9 |
| 火災危険 | This chemical is combustible. (NTP, 1992) |
| 健康有害性 | SYMPTOMS: Symptoms of exposure to this compound may include irritation of the skin and eyes, and allergic dermatitis. |
| 有害性の概要 | May cause skin sensitization[ICSC] Danger of skin sensitization[MAK] |
| 反応性グループ | Ethers |
| EC 分類 | Symbol: Xn, NR: 38-43-68-51/53S: (2)-36/37-61Note: C |
| Reactivity Profile | O-CRESYL GLYCIDYL ETHER may attack some forms of plastics. (NTP, 1992) |
| Chemical Dangers | The substance can presumably form explosive peroxides. Reacts with acids, amines, bases and strong oxidants. |
| Air and Water Reactions | Insoluble in water. |
| Hazard Classes and Categories | Skin Irrit. 2 (100%)Skin irritation - category 2Serious eye damage/eye irritation - Category 2BSkin sensitization - Category 1ASkin corrosion/irritation - Category 2Muta. 2 |
| 消火 | Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)Use water spray, foam, powder, carbon dioxide. |
| 応急処置措置 | Fresh air, rest.Remove contaminated clothes. Rinse and then wash skin with water and soap.First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.Rinse mouth. |
| 応急処置 | EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. |
| 安全保管 | Separated from strong oxidants, strong bases, strong acids and amines. Cool. Keep in the dark. |
| 非火災時の漏出対応 | SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. |
| 漏出処分 | Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in covered containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. |
| Isolation and Evacuation | Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: |
| Eye Prevention | Wear safety goggles or eye protection in combination with breathing protection. |
| Fire Prevention | NO open flames. |
| Inhalation Risk | No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C. |
| Skin Prevention | Protective gloves. Protective clothing. |
| Exposure Prevention | AVOID ALL CONTACT! |
| 有害作用 | Skin Sensitizer - An agent that can induce an allergic reaction in the skin. |
| Signs and Symptoms | Cough. Sore throat.Redness. Pain. |
| Toxicity Data | LC50 (rat) = 6,090 mg/m3/4h |
| 水環境危害等級（WGK） | 2 |
| TSCA 収載状態 | TSCA listed |
| RTECS 番号 | TZ3700000 |
| 輸送番号（UN） | UN 3082 9/PG 3 |
| 税関コード | 29109000 |
| 危険文句（R） | 36/37/38-68-51/53-43-38 |
| 危険表示 | Xi,N,Xn |
| 安全措置（S） | 26-37/39-61-36/37 |
| 危険等級 | 9Aquatic Chronic 2Muta. 2Skin Irrit. 2Skin Sens. 1A |
| 包装等級 | III |
| 貯蔵分類 | 10 - Combustible liquids |
用途
一般的な説明
Clear light yellow liquid.