ビスステアリン酸カドミウム

Cadmium stearate

HCID 16681CAS 101012-93-5

基本情報

標準SMILES
CCCCCCCCCCCCCCCCCC(=O)[O-].CCCCCCCCCCCCCCCCCC(=O)[O-].[Cd+2]
InChIKey
GWOWVOYJLHSRJJ-UHFFFAOYSA-L
分子式
C36H70CdO4
平均分子量
679.4 g/mol
単同位体質量
680.430776

名称と識別子

優先名称
Cadmium stearate
IUPAC
cadmium(2+);bis(octadecanoate)
現地名
ビスステアリン酸カドミウム
英語名
Cadmium stearate
分子式
C18H36CdO2
分子量
396.9

名称と別名

CADMIUM STEARATE2223-93-0Cadmium(II) stearateOctadecanoic acid, cadmium saltStabilizer SCDCadmium distearateCadmium octadecanoateStabilisator scdAlaixol 11KadmiumstearatStearic acid, cadmium saltCadmium soaps (stearate)
名称をさらに表示
ビスオクタデカン酸カドミウムジオクタデカン酸カドミウムビス(ステアリン酸)カドミウムジステアリン酸カドミウムビスステアリン酸カドミウムステアリン酸カドミウムステアリン酸カドミウム(II)scdFADS5hSCD1SCDOSMSTP008alaixol11stabilizerscddmium stearatestabilisatorscd
GBI2ILV46JOctadecanoic acid, cadmium salt (2:1)DTXSID30890557RefChem:1080615DTXCID801029805218-743-6cadmium(2+);octadecanoate101012-93-5

データベース識別子

CAS
101012-93-5、2223-93-0
PubChem CID
16681
DTXSID
DTXSID30890557
UNII
GBI2ILV46J
EC Number
218-743-6、309-794-6
Nikkaji
J42.505B

物性

構造計算による物性

極性表面積
80.3 Ų
水素結合供与体数
0
水素結合受容体数
4
回転可能結合数
30
重原子数
41

実験および物理化学的性質

DensityFree fatty acid: 2 wt%; total ash 19-20 wt%; moisture: 1 wt%. Bulk density: 180 g/L
Color/Form · 2 件

White powder

Solid

DecompositionWhen heated to decomposition it emits toxic fumes of /cadmium/.
Melting Point105-115 °C
Physical Description · 2 件

Cadmium stearate is a solid. Used as a lubricant and stabilizer for polyvinyl chloride. (EPA, 1998)

Solid; [CAMEO] White powder; [MSDSonline]

物理化学的性質

融点
103 · 103~110℃
比重(密度)
1.28 g/cm3 · 1.28g/cm3
色
white crystals, crystalline powder
CAS データベース
2223 · 2223-93-0(CAS DataBase Reference)
NISTの化学物質情報
Cadmium(II) n-octadecanoate(2223-93-0)
EPAの化学物質情報
Cadmium stearate (2223-93-0)

化学的性質

化学的特性Cadmium stearate is a crystalline solid.

安全と法規制

GHS分類

GHS Classification · 6 件

Danger

H302+H312 (25.3%): Harmful if swallowed or in contact with skin [Warning Acute toxicity, oral; acute toxicity, dermal];H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral];H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal];H330 (25.3%): Fatal if inhaled [Danger Acute toxicity, inhalation];H332 (74.7%): Harmful if inhaled [Warning Acute toxicity, inhalation];H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard];H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

P260, P261, P264, P270, P271, P273, P280, P284, P301+P317, P302+P352, P304+P340, P316, P317, P320, P321, P330, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 154 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Regulatory Information · 6 件

Chemical: Octadecanoic acid, cadmium salt

Chemical: Octadecanoic acid, cadmium salt, basic

Restricted substance: Cadmium distearate;EC: 218-743-6;Restriction condition document: PDF link

Restricted substance: Octadecanoic acid, cadmium salt, basic;EC: 309-794-6;Restriction condition document: PDF link

Cadmium stearate: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

Other Safety Information · 2 件

IMAP assessments - Cadmium(2+) salts of medium- and long-chain carboxylic acids: Environment tier II assessment;IMAP assessments - Cadmium salts of selected fatty acids: Human health tier II assessment

IMAP assessments - Cadmium(2+) salts of medium- and long-chain carboxylic acids: Environment tier II assessment;IMAP assessments - Cadmium salts of selected fatty acids: Human health tier II assessment

DOT LabelPoison
Fire HazardsIt emits acrid smoke when heated to decomposition. (EPA, 1998)
Health Hazards · 1 件

Similar to cadmium; acute toxicity most notably occurs secondary to cadmium ingestion or inhalation of cadmium fumes. Poisoning from inhalation is relatively rare but dangerous, having a mortality rate of about 15 percent. Toxic inhaled concentrations in humans have been reported at 147 mg/m3/35 minutes and at 1800 mg/m3/2 years. (EPA, 1998)

Hazards SummaryMay cause irritation; Inhalation or ingestion may cause cadmium poisoning; [MSDSonline] See Cadmium and the linked diseases.

安全と保護具

Fire Fighting · 1 件

(Non-Specific -- Cadmium Compound) Keep upwind; keep out of low areas. Wear self-contained (positive pressure if available) breathing apparatus and full protective clothing.;(Non-Specific -- Cadmium Compound) For small fires, use dry chemicals, carbon dioxide, water spray, or foam. For large fires, use water spray, fog, or foam. (EPA, 1998)

First Aid · 1 件

Warning: Effects may be delayed for several hours. Caution is advised.;Signs and Symptoms of Acute Cadmium Stearate Exposure: The following signs and symptoms may be noted following exposure to cadmium stearate: cough, dyspnea (shortness of breath), either dry mouth or increased salivation, abdominal pain, nausea, vomiting, bronchitis, and chest pain. Vertigo (dizziness), fever, and profuse sweating may also occur.;Emergency Life-Support Procedures: Acute exposure to cadmium stearate may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.;Inhalation Exposure:;1. Move victims to fresh air. Emergency personnel should avoid self-exposure to cadmium stearate.;2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.;3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.;4. Transport to a health care facility.;Dermal/Eye Exposure:;1. Remove victims from exposure. Emergency personnel should avoid self- exposure to cadmium stearate.;2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.;3. Remove contaminated clothing as soon as possible.;4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.;5. Wash exposed skin areas THOROUGHLY with soap and water.;6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.;7. Transport to a health care facility.;Ingestion Exposure:;1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.;2. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.;3. Vomiting may be induced with syrup of Ipecac. If elapsed time since ingestion of cadmium stearate is unknown or suspected to be greater than 30 minutes, do not induce vomiting and proceed to Step

Exposure Control and Personal Protection · 1 件

Biological Exposure Indices (BEI) [ACGIH] - Cd in urine = 5 ug/g creatinine; Cd in blood = 5 ug/L; sampling time not critical; Monitoring in blood should be preferred during the initial year of exposure and whenever changes in the degree of exposure are suspected. [ACGIH];TIH (Toxic Inhalation Hazard) - Term used to describe gases and volatile liquids that are toxic when inhaled. Some are TIH materials themselves, e.g., chlorine, and some release TIH gases when spilled in water, e.g., chlorosilanes. [ERG 2016].

Fire Fighting Procedures · 1 件

If material on fire or involved in fire: Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Use water in flooding quantities as fog. Use "alcohol" foam, dry chemical or carbon dioxide. /Cadmium compounds, NOS/

Nonfire Spill Response · 1 件

(Non-Specific -- Cadmium Compounds) Do not touch spilled material. Stay upwind; keep out of low areas. Take up small spills with sand or other noncombustible absorbent material and place into containers for later disposal. Take up small, dry spills with clean shovel and place into clean, dry container. Dike far ahead of large spills for later disposal. (EPA, 1998)

Disposal Methods · 3 件

Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number D006, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste. /Cadmium/

Precipitate from solution as sulfides, drying and return to suppliers. /Cadmium compounds/

The following wastewater treatment technology has been investigated for cadmium: Concentration process: Reverse Osmosis. /Cadmium/

毒性情報

Ecotoxicity Values · 3 件

LC50; Species: Oncorhynchus mykiss (Rainbow Trout) fingerling, length 6 cm, weight 2.5 g; Conditions: freshwater, static, 16.8 °C, pH 7.2-7.3; Concentration: 5.2 ug/L for 10 days /total Cd ion/

LC50; Species: Oncorhynchus mykiss (Rainbow Trout) fingerling, length 6 cm, weight 2.5 g; Conditions: freshwater, static, 16.8 °C, pH 7.2-7.3; Concentration: 7.5 ug/L for 48 hr /total Cd ion/

LC50; Species: Oncorhynchus mykiss (Rainbow Trout) fingerling, length 6 cm, weight 2.5 g; Conditions: freshwater, static, 16.8 °C, pH 7.2-7.3; Concentration: 6 ug/L for 96 hr /total Cd ion/

Adverse Effects · 1 件

Nephrotoxin - The chemical is potentially toxic to the kidneys in the occupational setting.;Reproductive Toxin - A chemical that is toxic to the reproductive system, including defects in the progeny and injury to male or female reproductive function. Reproductive toxicity includes developmental effects. See Guidelines for Reproductive Toxicity Risk Assessment.

Medical Surveillance · 1 件

In preemployment physical examinations emphasis should be given to a history of, or actual presence of, significant kidney disease, smoking history, and respiratory disease. A chest x-ray and baseline pulmonary function study is recommended. Periodic examinations should emphasize the respiratory system, including pulmonary function tests, kidneys, and blood. A low molecular weight proteinuria may be the earliest indication of renal toxicity. The trichloroacetic acid test may pick this up, but more specific quantitative studies would be preferable. If renal disease due to cadmium is present, there may also be increased excretion of calcium, amino acids, glucose, and phosphates. /Cadmium and compounds/

Human Toxicity Excerpts · 3 件

/HUMAN EXPOSURE STUDIES/ In 1963, 27 exposed and 7 non-exposed workers from a polyvinyl chloride film plant in which lead and cadmium sterates were used as stablilzers /showed that/ urinary coproporphyrin levels were not increased in exposed workers compared to that of controls, and most of the urinary lead levels were below 200 ug/L. Although lead concentrations were higher than those of cadmium, particle sizes of lead compounds were larger than those of the cadmium stearate. Eight of 17 workers re-examined in 1964 had increases in the degree of urinary protein excretion by the trichloroacetic acid (TCA) test. The numbers that were positive were significantly greater in the exposed workers, than in the controls in the 1964 tests. Statistically, this might possibly have been due to the larger number of controls, and therefore, to a more normal distribution curve which is apparent in the 1964 data (24 controls in 1964 vs 7 controls in 1963). These increases were demonstrated by all three methods of testing for urinary protein, ... 25% TCA test, sulfosalicylic acid test, and boiling test. ... No significant differences in respiratory function were found between exposed and control groups. No significant differences in mean urinary cadmium levels were demonstrated, though there were a few slightly higher urinary cadmium levels in the exposed group. No differences in olfactory acuity between the two groups were shown. Yellow discoloration of the teeth of exposed workers was looked for but not found. Liver function ... was not significantly different in exposed and control groups. ... There were no significant differences in hemoglobin, urine specific gravity, urine occult blood, but there was a slight increase in urine sugar (by test tape) in exposed workers /over/ controls. Both groups had less than 0.05% of cells with basophillic stippling. ... Each work operation, involving exposure to lead stearate and cadmium stearate, as well as to organic plasticizers, took 20 mi

/SIGNS AND SYMPTOMS/ Chronic cadmium poisoning has been reported after prolonged occupational exposure to ... cadmium stearates. Changes associated with chronic cadmium poisoning may be local, in which case they involve the respiratory tract, or systemic, resulting from absorption of cadmium. Systemic changes include kidney damage with proteinuria and anemia. Obstructive lung disease in the form of emphysema is the main symptom at heavy exposure to cadmium in air, whereas kidney dysfunction and damage are the most prominent findings after long term exposure to lower levels of cadmium in workroom air or via cadmium contaminated food. Mild hypochromic anemia is frequently found among workers exposed to high levels of cadmium. This may be due to both increased destruction of red blood cells and iron deficiency. Yellow discoloration of the necks of teeth and anosmia may also be seen in cases of exposure to very high cadmium concentrations.

/OTHER TOXICITY INFORMATION/ ... /CADMIUM SOAPS SUCH AS CADMIUM STEARATE/ CAN GIVE RISE TO THE CORRESPONDING METAL CHLORIDES, WHICH ARE BOTH SOLUBLE AND TOXIC, WHEN THEY STABILIZE THE VINYL RESIN. HENCE THEY CANNOT BE USED TO PREPARE VINYL COMPOUNDS WHICH WILL BE USED IN THE FOOD INDUSTRY.

Non-Human Toxicity Excerpts · 3 件

/LABORATORY ANIMALS: Acute Exposure/ MALE RATS WERE GIVEN A SINGLE INTRATRACHEAL DOSE OF 10 MG CADMIUM STEARATE. TWO MONTHS AFTER THE ADMINISTRATION, THERE WAS ULCERATION WITH LEUKOCYTIC REACTION, SYMPTOMS OF PNEUMOSCLEROSIS, CHRONIC PNEUMONIA, BRONCHOLITHIASIS, AND WIDESPREAD HEMORRHAGES. IN 4-6 MONTHS THEY SHOWED DILATION OF THE LARGE BRONCHI, THE ACCUMULATION OF LYMPHOCYTES, DIFFUSE PNEUMOSCLEROSIS, CHRONIC EMPHYSEMA, AND SMALL HEMORRHAGIC AREAS.

/LABORATORY ANIMALS: Neurotoxicity/ CADMIUM STEARATE AT 0.58X10-6 MOLAR INHIBITED THE NERVE FIBER AND GLIAL CELL OUTGROWTH FROM CULTURED SLICES OF CEREBELLUM OF 5-9 DAY OLD RATS, AND CAUSED FORMATION OF GRANULES IN THE NERVE FIBERS AND FIBROBLASTS.

/OTHER TOXICITY INFORMATION/ ORAL DOSES OF CADMIUM STEARATE (550 MG/KG) INDUCED TESTICULAR INFLAMMATION IN RATS.

Evidence for Carcinogenicity · 3 件

CLASSIFICATION: B1; probable human carcinogen. BASIS FOR CLASSIFICATION: Limited evidence from occupational epidemiologic studies of cadmium is consistent across investigators and study populations. There is sufficient evidence of carcinogenicity in rats and mice by inhalation and intramuscular and subcutaneous injection. Seven studies in rats and mice wherein cadmium salts (acetate, sulfate, chloride) were administered orally have shown no evidence of carcinogenic response. HUMAN CARCINOGENICITY DATA: Limited. /Classification based on former EPA guidelines/

A2; Suspected human carcinogen. /Cadmium and compounds, as Cd/

Cadmium and Cadmium Compounds: known to be human carcinogens.

法規制情報

Regulatory Information · 6 件

Chemical: Octadecanoic acid, cadmium salt

Chemical: Octadecanoic acid, cadmium salt, basic

Restricted substance: Cadmium distearate;EC: 218-743-6;Restriction condition document: PDF link

Restricted substance: Octadecanoic acid, cadmium salt, basic;EC: 309-794-6;Restriction condition document: PDF link

Cadmium stearate: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

RCRA Requirements · 1 件

D006; A solid waste containing cadmium may or may not become characterized as a hazardous waste when subjected to the Toxicity Characteristic Leaching Procedure listed in 40 CFR 261.24, and if so characterized, must be managed as a hazardous waste. /Cadmium/

Atmospheric Standards · 1 件

Listed as a hazardous air pollutant (HAP) generally known or suspected to cause serious health problems. The Clean Air Act, as amended in 1990, directs EPA to set standards requiring major sources to sharply reduce routine emissions of toxic pollutants. EPA is required to establish and phase in specific performance based standards for all air emission sources that emit one or more of the listed pollutants. Cadmium stearate is included on this list.

CERCLA Reportable Quantities · 1 件

Releases of CERCLA hazardous substances are subject to the release reporting requirement of CERCLA section 103, codified at 40 CFR part 302, in addition to the requirements of 40 CFR part 355. Cadmium stearate is an extremely hazardous substance (EHS) subject to reporting requirements when stored in amounts in excess of its threshold planning quantity (TPQ) of 1,000 or 10,000 lbs. Extremely hazardous substances that are solids are subject to either of two threshold planning quantities ... The lower quantity applies only if the solid exists in powdered form and has a particle size less than 100 microns; or is handled in solution or in molten form; or meets the criteria for a National Fire Protection Association (NFPA) rating of 2, 3 or 4 for reactivity. If the solid does not meet any of these criteria, it is subject to the upper ... threshold planning quantity ... .

Clean Water Act RequirementsToxic pollutant designated pursuant to section 307(a)(1) of the Federal Water Pollution Control Act and is subject to effluent limitations. /Cadmium and compounds/
State Drinking Water Standards(AZ) ARIZONA 10 ug/L /Cadmium/

安全データ

tsca
TSCA listed
ridadr
2570
毒性
LD50 orl-rat: 1125 mg/kg GISAAA 35(2),98,70
PRTR法
第1種指定化学物質(特定物質)
risk_code
20/21/22-50/53
化審法
2-615

化学と産業

薬理情報

Biological Half-LifeSLOW EXCRETION RESULTS IN VERY LONG BIOLOGICAL HALF LIFE FOR ABSORBED CADMIUM, WHICH HAS BEEN EST TO BE 16-33 YR ... . /CADMIUM/
Absorption, Distribution and Excretion · 5 件

THE PERCUTANEOUS ABSORPTION OF CADMIUM STEARATE WAS INVESTIGATED IN MICE, RATS, GUINEA PIGS, AND RABBITS. IT PENETRATES THE INTACT SKIN EASILY AND IS RETAINED IN THE LIVER AND KIDNEYS FOR A LONG PERIOD BEFORE IT IS SLOWLY EXCRETED.

Gastrointestinal absorption is less than respiratory absorption and is about 5 to 8 percent. It is enhanced by dietary deficiencies of calcium and iron, and diets low in protein. Low dietary calcium stimulates synthesis of calcium binding protein which enhances cadmium absorption. Women with low serum ferritin levels have been shown to have twice the normal absorption of cadmium. Zinc decreases cadmium absorption probably by stimulating production of metallothionein. /Cadmium/

Excretion by feces of normal humans is ca 30-50 ug/day ... retention of ingested cadmium varied between 4.7-7% in 5 adult men ... only very small proportions of daily absorbed dose will be excreted ... normal urinary excretion in humans amount to CA 1-2 ug/day ... on occupational exposure, this level is not raised significantly ... . /Cadmium/

EXCRETION BY FECES OF NORMAL HUMANS IS ABOUT 30-50 UG/DAY ... RETENTION OF INGESTED CADMIUM VARIED BETWEEN 4.7-7% IN 5 ADULT MEN ... ONLY VERY SMALL PROP OF DAILY ABSORBED DOSE WILL BE EXCRETED ... NORMAL URINARY EXCRETION IN HUMANS AMT TO ABOUT 1-2 UG/DAY ... ON OCCUPATIONAL EXPOSURE, THIS LEVEL IS NOT RAISED SIGNIFICANTLY ... /CADMIUM/

About half of total body burden is found in liver & kidneys. Cadmium in these organs is mainly bound to /a/ low molecular weight protein, in form of metallothionein ... . /Cadmium/

用途と製造

Uses · 4 件

Used as lubricant and heat stabilizer in PVC plastics; [HSDB] Metallic soaps such as cadmium stearate are used as thickeners, lubricants, release agents, and drying agents; [Ullmann]

Lubricant and stabilizer in plastics.

An organocadmium soap incorporated into plastics to prevent early discoloration

Heat stabilizer in PVC plastics

U.S. Production · 4 件

(1979) PROBABLY GREATER THAN 2.27X10+6 G

(1981) PROBABLY GREATER THAN 2.27X10+6 G

Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#5425]

Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: Octadecanoic acid, cadmium salt. Aggregated National Production Volume: < 500,000 pounds.

Methods of Manufacturing · 2 件

REACTION OF CADMIUM CHLORIDE WITH SODIUM STEARATE

... Prepared from cadmium chloride solution by precipitation with sodium salt of the fatty acid.

General Manufacturing Information · 3 件

Octadecanoic acid, cadmium salt (2:1): ACTIVE

FDA regulations have decreed that plastics that contact foodstuffs may not contain Cd-Ba stabilizers ... a decrease in consumption of Cd compounds in the stabilizer field that began in the late 1970s.

CADMIUM SOAPS (STEARATE) ... ARE REMARKABLE FOR THE HIGH DEGREE OF TRANSPARENCY WHICH, EVEN IN SMALL AMOUNTS, THEY IMPART TO VINYL FILM (SHEET).

応用分野

一般的な説明Solid. Used as a lubricant and stabilizer for polyvinyl chloride.

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