硫酸アンモニウム=ドデシル

Ammonium lauryl sulfate appears as light yellow liquid. May float or sink and mix with water. (USCG, 1999)

Liquid

Clear liquid; [HSDB] Light yellow liquid; [CAMEO] Commercial material is liquid; Pure material is light yellow solid; [CHEMINFO] Opaque yellow liquid (30% aqueous solution); [MSDSonline]

This chemical does not meet GHS hazard criteria for 0.3% (2 of 617) of reports.

Danger

H302 (71.8%): Harmful if swallowed [Warning Acute toxicity, oral]；H315 (27.9%): Causes skin irritation [Warning Skin corrosion/irritation]；H318 (17.7%): Causes serious eye damage [Danger Serious eye damage/eye irritation]；H319 (82%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

P264, P264+P265, P270, P280, P301+P317, P302+P352, P305+P351+P338, P305+P354+P338, P317, P321, P330, P332+P317, P337+P317, P362+P364, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 617 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 2 of 617 reports by companies.；There are 8 notifications provided by 615 of 617 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Chemical: Sulfuric acid, monododecyl ester, ammonium salt

Sulfuric acid, monododecyl ester, ammonium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Sulfuric acid, monododecyl ester, ammonium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Dodecyl ammonium sulphate: Does not have an individual approval but may be used under an appropriate group standard

A skin and eye irritant; Emergency treatment: Detergents and soaps- anionic and nonionic; [HSDB] Moderate eye irritant and severe skin irritant in rabbits; [RTECS] Concentrations greater than 20% may be corrosive to skin and eyes; [CHEMINFO] An irritant; May cause serious eye injury; May cause respiratory sensitization (28% aqueous solution); [Medisca MSDS]

As the federal pesticide law FIFRA directs, EPA is conducting a comprehensive review of older pesticides to consider their health and environmental effects and make decisions about their future use. Under this pesticide reregistration program, EPA examines health and safety data for pesticide active ingredients initially registered before November 1, 1984, and determines whether they are eligible for reregistration. In addition, all pesticides must meet the new safety standard of the Food Quality Protection Act of 1996. Pesticides for which EPA had not issued Registration Standards prior to the effective date of FIFRA, as amended in 1988, were divided into three lists based upon their potential for human exposure and other factors, with List B containing pesticides of greater concern and List D pesticides of less concern. Ammonium lauryl sulfate is found on List D. Case No: 4061; Pesticide type: insecticide, fungicide, rodenticide, antimicrobial; Case Status: RED Approved 09//93; OPP has made a decision that some/all uses of the pesticide are eligible for reregistration, as reflected in a Reregistration Eligibility Decision (RED) document.; Active ingredient (AI): Ammonium lauryl sulfate; AI Status: The active ingredient is no longer contained in any registered pesticide products ... "cancelled."

Acidic inorganic salts, such as AMMONIUM LAURYL SULFATE, are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid.

Acute Tox. 4 (71.8%)；Skin Irrit. 2 (27.9%)；Eye Dam. 1 (17.7%)；Eye Irrit. 2 (82%)

Eye damage - category 1；Skin irritation - category 2；Specific target organ toxicity (single exposure) - category 3；Acute toxicity (dermal) - category 4；Acute toxicity (ingestion) - category 4

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Rubber gloves; goggles or face shield (USCG, 1999)

Personal Protective Equipment: Rubber gloves; googles or face shield

Sodium Lauryl Sulfate and Ammonium Lauryl Sulfate appear to be safe in formulations designed for discontinuous, brief use followed by thorough rinsing from the surface of the skin. In products intended for prolonged contact with skin, concentrations should not exceed 1%.

Safe for use in cosmetics, with qualifications

While ammonium lauryl sulfate itself is not toxic, it is a nitrosating agent. Nitrosating agents may decompose and/or react to cause nitrosamine contamination. Nitrosamines are produced from secondary amines and amides in the presence of nitrite ions and are believed to be carcinogenic. Once in the body, nitrosamines are activated by cytochrome P-450 enzymes. They are then believed to induce their carcinogenic effects by forming DNA adducts at the N- and O-atoms. (L1889, L1890, A2878, A2879, A2880)

BRANCHED-CHAIN PRODUCTS HAVE...SIGNIFICANT PERCUTANEOUS TOXICITY. SKIN IRRITATION MAY BE ENCOUNTERED... /ALKYL SODIUM SULFATES/

Contact with liquid irritates eyes and may have drying effect on the skin. Prolonged contact will cause skin irritation.

SURFACTANTS FOR PREPN OF MYCOBACTERIAL SUSPENSIONS CAUSED INDUCTION OF CHROMOGENIC STRAINS IN M TUBERCULOSIS & BOVIS, AMMONIUM LAURYL SULFATE WAS LESS EFFECTIVE THAN NA LAURYL SULFATE. GUINEA PIGS INOCULATED WITH THESE STRAINS SHOWED NO TUBERCULOUS LESIONS.

EVALUATION OF IRRITANCY OF SURFACE ACTIVE AGENTS UPON UPPER RESP TRACT OF GUINEA-PIGS, MICE & RABBITS.

Chemical: Sulfuric acid, monododecyl ester, ammonium salt

Sulfuric acid, monododecyl ester, ammonium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Sulfuric acid, monododecyl ester, ammonium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Dodecyl ammonium sulphate: Does not have an individual approval but may be used under an appropriate group standard

As the federal pesticide law FIFRA directs, EPA is conducting a comprehensive review of older pesticides to consider their health and environmental effects and make decisions about their future use. Under this pesticide reregistration program, EPA examines health and safety data for pesticide active ingredients initially registered before November 1, 1984, and determines whether they are eligible for reregistration. In addition, all pesticides must meet the new safety standard of the Food Quality Protection Act of 1996. Pesticides for which EPA had not issued Registration Standards prior to the effective date of FIFRA, as amended in 1988, were divided into three lists based upon their potential for human exposure and other factors, with List B containing pesticides of greater concern and List D pesticides of less concern. Ammonium lauryl sulfate is found on List D. Case No: 4061; Pesticide type: insecticide, fungicide, rodenticide, antimicrobial; Case Status: RED Approved 09//93; OPP has made a decision that some/all uses of the pesticide are eligible for reregistration, as reflected in a Reregistration Eligibility Decision (RED) document.; Active ingredient (AI): Ammonium lauryl sulfate; AI Status: The active ingredient is no longer contained in any registered pesticide products ... "cancelled."

CIR ingredient: Ammonium Lauryl Sulfate

Used as an anionic detergent or surface-active agent in hair and rug shampoos, bath products, detergents, skin cleansing preparations, hand soaps, hair dyes, conditioners, and shaving products; [CHEMINFO]

Dressing Hair [Category: Other]

The active ingredient is no longer contained in any registered pesticide products ... "cancelled."

SURFACE-ACTIVE INGREDIENT OF HAIR SHAMPOOS, RUG SHAMPOOS

ANIONIC DETERGENT /ALKYL SODIUM SULFATES/

2023: 250,000 - <400,000 lb；2022: 1,000,000 - <5,000,000 lb；2021: 1,000,000 - <5,000,000 lb；2020: 550,000 - <700,000 lb

(1972) 1.21X10+9 GRAMS

EPA Safer Chemical Functional Use Classes -> Surfactants

Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

Cosmetics -> Cleansing; Foaming; Surfactant

Soap, Cleaning Compound, and Toilet Preparation Manufacturing；All Other Basic Organic Chemical Manufacturing

Sulfuric acid, monododecyl ester, ammonium salt (1:1): ACTIVE