CAS 69304-37-6 1,3-Dichlorotetraisopropyldisiloxane (HCID 172404)

名称と識別子

優先名称: 1,3-Dichlorotetraisopropyldisiloxane
IUPAC: chloro-[chloro-di(propan-2-yl)silyl]oxy-di(propan-2-yl)silane
現地名: 1,3-ジクロロ-1,1,3,3-テトライソプロピルジシロキサン
英語名: 1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane
分子式: C12H28Cl2OSi2
分子量: 315.43

名称と別名

69304-37-6Tipdsicl21,3-DichlorotetraisopropyldisiloxaneDisiloxane, 1,3-dichloro-1,1,3,3-tetrakis(1-methylethyl)-1,3-Dichloro-1,1,3,3-tetraisopropyl disiloxaneDTXSID10219363RefChem:72640DTXCID301418541,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane1,1,3,3-Tetraisopropyl-1,3-dichlorodisiloxaneMFCD00009655chloro-[chloro-di(propan-2-yl)silyl]oxy-di(propan-2-yl)silane

名称をさらに表示

1,3-ジクロロ-1,1,3,3-テトライソプロピルジシロキサン1,3-ジクロロ-1,1,3,3-テトライソプロピルプロパンジシロキサン1,3-ジクロロ-1,1,3.3-テトライソプロピルジシロキサン1,1,3,3-テトライソプロピル-1,3-ジクロロプロパンジシロキサンビス(クロロジイソプロピルシリル)エーテル2,6-ジメチル-3,5-ジクロロ-3,5-ジイソプロピル-4-オキサ-3,5-ジシラヘプタン1，3ジクロロ1，1，3，3テトライソプロピルジシロキサンクロロ({[クロロビス(プロパン-2-イル)シリル]オキシ})ビス(プロパン-2-イル)シランTIPSCL1,3-Dichloro-1,1,3,3-tetrakis(1-methylethyl)disiloxaneDichloro-1,1,3,3-Tetraisopropyldisiloxane1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxanDK365DK870DKSI013

chloro-[chloro(diisopropyl)silyl]oxy-diisopropyl-silanechloro({[chlorobis(propan-2-yl)silyl]oxy})bis(propan-2-yl)silaneS06200C12H28Cl2OSi21,3-dichloro-1,1,3,3-tetraisopropyl-disiloxane1,1,3,3-Tetraisopropyl-1,3-dichlorodisiloxane; 1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane; 1,3-Dichlorotetraisopropyldisiloxane; TIPDS-Cl2; Tetraisopropyldisiloxane-1,3-diyl DichlorideTIPDSi-Cl2SCHEMBL131740

データベース識別子

CAS: 69304-37-6
PubChem CID: 172404
DTXSID: DTXSID10219363
EC Number: 629-558-9
Nikkaji: J208.383C

物性

構造計算による物性

極性表面積: 9.2 Å²
水素結合供与体数: 0
水素結合受容体数: 1
回転可能結合数: 6
重原子数: 17
形式電荷: 0
複雑度: 203

実験および物理化学的性質

Physical DescriptionClear colorless liquid; [Aldrich MSDS]

物理化学的性質

沸点: 70 °C0.5 · 70 °C0.5 mm Hg(lit.)
比重(密度): 0.986 g/mL · 0.986 g/mL at 25 °C(lit.)
屈折率: 20 · n20/D 1.454(lit.)
闪点: 230 °F · >230 °F
貯蔵温度: 2 · Inert atmosphere,2-8°C
溶解性: ジメチルホルムアミド、ヘキサン、酢酸エチル、クロロホルム、ジクロロメタンと混和します。
外見: 油
色: 無色
比重: 0.986 · 0.986
BRN: 1934216 · 1934216
InChI: InChI=1S/C12H28Cl2OSi2/c1-9(2)16(13,10(3)4)15-17(14,11(5)6)12(7)8/h9-12H,1-8H3
InChIKey: DDYAZDRFUVZBMM-UHFFFAOYSA-N
SMILES: [Si](Cl)(C(C)C)(C(C)C)O[Si](Cl)(C(C)C)C(C)C
CAS データベース: 69304 · 69304-37-6(CAS DataBase Reference)

化学的性質

化学的特性Colorless liquid

安全と法規制

GHS分類

GHS Classification · 5 件

Danger

H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P264, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P363, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 49 reports by companies from 5 notifications to the ECHA C&L Inventory.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Regulatory Information1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryCauses burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; [Aldrich MSDS] See CHLOROSILANES.

Hazard Classes and CategoriesSkin Corr. 1B (100%)

毒性情報

Adverse EffectsDermatotoxin - Skin burns.；Toxic Pneumonitis - Inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors.

法規制情報

Regulatory Information1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane: Does not have an individual approval but may be used under an appropriate group standard

安全データ

F: 10-21
wgk: 3
tsca: No
ridadr: UN 3265 8/PG 2
hs_code: 29319090
risk_code: 34
化審法: (2)-3942
消防法: 危-4-3-III
hazard_code: C
hazard_note: Corrosive
safety_code: 26-27-28-36/37/39-45
hazard_class: 8
packing_group: II

化学と産業

用途と製造

UsesSilyl reagent which allows for simultaneous protection of 3'- & 5'-hydroxy functions of ribonucleosides. [ChemIDplus]

応用分野

使用1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane is used in the analysis of Watson-Crick and Hoogstein base pairing in nucleotides. Also used in the formation of ribavirin chemical delivery systems.

調製方法 · 1 件

製造方法can be prepared starting from trichlorosilane by treatment with i-PrMgCl, H2O, and acetyl chloride. Alternatively, it can be prepared by the reaction of 1,1,3,3- tetraisopropyldisiloxane with CCl4 in the presence of catalytic PdCl2.This method is also suitable for its in situ preparation.