3-グリシジルオキシプロピルトリメトキシシラン

Glycidoxypropyltrimethoxysilane

HCID 17317CAS 233765-90-7

部分構造検索類似構造を探す

基本情報

標準SMILES: CO[Si](CCCOCC1CO1)(OC)OC
InChIKey: BPSIOYPQMFLKFR-UHFFFAOYSA-N
分子式: C9H20O5Si
平均分子量: 236.34 g/mol
単同位体質量: 236.10800027

概要

See also: Glycidylpropyltrimethoxysilane homopol.~ (annotation moved to).

名称と識別子

優先名称: Glycidoxypropyltrimethoxysilane
IUPAC: trimethoxy-[3-(oxiran-2-ylmethoxy)propyl]silane
現地名: 3-グリシジルオキシプロピルトリメトキシシラン
英語名: 3-Glycidoxypropyltrimethoxysilane
分子式: C9H20O5Si
分子量: 236.34

名称と別名

2530-83-8Silan A 187Silicone KBM 403Silane A 187Silane Z 6040GlycidoxypropyltrimethoxysilaneNUCA 1873-(Trimethoxysilyl)propyl glycidyl ethergamma-GlycidoxypropyltrimethoxysilaneGlycidyloxypropyltrimethoxysilaneKBM 403KBM 430

名称をさらに表示

3-グリシジルオキシプロピルトリメトキシシラン[3-(オキシラン-2-イルメトキシ)プロピル]トリメトキシシランγ-グリシドキシプロピルトリメトキシシラン1-(トリメトキシシリル)-3-(グリシジルオキシ)プロパントリメトキシ[3-(オキシラニルメトキシ)プロピル]シラン(γ-グリシジルオキシプロピル)トリメトキシシラン1-(トリメトキシシリル)-3-(オキシラニルメトキシ)プロパングリシドキシプロピルトリメトキシシラン2-[[3-(トリメトキシシリル)プロポキシ]メチル]オキシラン3-グリシドキシプロピルトリメトキシシラン[3-(グリシジルオキシ)プロピル]トリメトキシシラントリメトキシ[3-(オキシラン-2-イルメトキシ)プロピル]シラン3-(トリメトキシシリル)プロピル(オキシラニルメチル)エーテル[[3-(トリメトキシシリル)プロポキシ]メチル]オキシラン[3-(オキシラニルメトキシ)プロピル]トリメトキシシラングリシジル[3-(トリメトキシシリル)プロピル]エーテルトリメトキシ[3-(グリシジルオキシ)プロピル]シランシランY-40873-(オキシラニルメトキシ)プロピルトリメトキシシラントリメトキシ[3-[(オキシラニル)メトキシ]プロピル]シランKH-560GLYMO3-GLYCIDYLOXYPROPYLTRIMETHOXYSILANEγ-Glycidoxypropyltrimethoxysilane3-(2,3-EPOXYPROPOXY)PROPYLTRIMETHOXYSILANESilane coupling agent KH-560γ-(2,3-epoxypropoxy)propytrimethoxysilaneGF80GOPTS

DZ 6040A 187Y 4087Z 6040(3-(2,3-Epoxypropoxy)propyl)trimethoxysilane5K9X9X899R[3-(2,3-Epoxypropoxy)propyl]trimethoxysilaneRefChem:922335

データベース識別子

CAS: 233765-90-7、2530-83-8、25704-87-4
PubChem CID: 17317
DTXSID: DTXSID5027489
ChEMBL: CHEMBL2140162
UNII: 5K9X9X899R
EC Number: 219-784-2、247-194-5、807-562-3
Nikkaji: J48.152A

物性

構造計算による物性

極性表面積: 49.5 Å²
水素結合供与体数: 0
水素結合受容体数: 5
回転可能結合数: 9
重原子数: 15
形式電荷: 0
複雑度: 166

実験および物理化学的性質

PolymersPlastics & Rubber -> Glycidyl Ethers

Density1.065-1.075 @25 °C

Boiling Point290 °C @760 [mm Hg]

Vapor Pressure0.002 [mmHg]

Physical Description · 2 件

Liquid; Dry Powder; Liquid

Liquid; [eChemPortal: SIDSUNEP] Clear colorless liquid; [MSDSonline]

物理化学的性質

融点: -50 °C · -50°C
沸点: 120 °C2 · 120 °C2 mm Hg(lit.)
比重(密度): 1.07 g/mL · 1.070 g/mL at 20 °C
蒸気圧: 0 · 0-12790Pa at 20-25℃
屈折率: 20 · n20/D 1.429(lit.)
闪点: 230 °F · >230 °F
貯蔵温度: 30 °C · Store below +30°C.
溶解性: アセトニトリル（微量）、クロロホルム
外見: 液体
色: クリア
比重: 1.07 · 1.07
水溶解度: アルコール、ケトン、脂肪族または芳香族炭化水素と混和します。水と混和しない。
BRN: 4308125 · 4308125
Henry's Law Constant: 1.4 · 1.4×102 mol/(m3Pa) at 25℃, Ebert et al. (2023)
安定性: 湿気に敏感
化粧品成分の機能: 爪のコンディショニング
InChI: 1S/C9H20O5Si/c1-10-15(11-2,12-3)6-4-5-13-7-9-8-14-9/h9H,4-8H2,1-3H3
InChIKey: BPSIOYPQMFLKFR-UHFFFAOYSA-N
SMILES: CO[Si](CCCOCC1CO1)(OC)OC
LogP: -2.6 · -2.6-0.5 at 20℃
CAS データベース: 2530 · 2530-83-8(CAS DataBase Reference)
NISTの化学物質情報: 3 · 3-Glycidoxypropyltrimethoxysilane(2530-83-8)
EPAの化学物質情報: 3 · 3-(Trimethoxysilyl)propyl glycidyl ether (2530-83-8)

化学的性質

化学的特性Colorless transparent liquid

安全と法規制

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 13.6% (281 of 2064) of reports.

Danger

H318 (54.1%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

P203, P264+P265, P273, P280, P305+P354+P338, P317, P318, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 2064 reports by companies from 31 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Warning

危険有害性情報

Regulatory Information · 6 件

Chemical: Silane, trimethoxy[3-(oxiranylmethoxy)propyl]-

Chemical: Silane, trimethoxy[(oxiranylmethoxy)propyl]-

Regulation (EC) No 1935/2004 (amended)

Oxirane, 2-[[3-(trimethoxysilyl)propoxy]methyl]- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Oxirane, 2-[[3-(trimethoxysilyl)propoxy]methyl]- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

TP - indicates a substance that is the subject of a proposed TSCA section 4 test rule.

Status: Active Update: 10-02-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/14972

Other Safety Information · 2 件

Evaluation - Chemicals that are unlikely to require further regulation to manage risks to environment

Hazards Summary · 1 件

Mildly irritating to skin and eyes; Not a known skin sensitizer; Rapidly hydrolyzes into methanol and silanetriols; Oral LD50 (rats) = 7010 to 16900 mg/kg and dermal LD50 (rats) = 6800 mg/kg; [OECD SIDS: Trimethoxy[3-(oxiranylmethoxy)propyl]-silane - 2004] May cause irritation; May form siloxane polymer on contact with skin, eyes, or lungs; [MSDSonline]

Hazard Classes and Categories · 3 件

Eye Dam. 1 (54.1%)

Skin Irrit. 2 (100%)

Serious eye damage/eye irritation - Category 1

安全と保護具

Protective Action Criteria (PAC) · 3 件

3.4 [mg/m3]

38 [mg/m3]

230 [mg/m3]

毒性情報

Toxicity DataLCLo (rat) =5,300 mg/m3/4h

安全データ

F: 10-21
wgk: 2
tsca: TSCA listed
rtecs: VV4025000
毒性: LD50 oral in rat: 22600uL/kg
hs_code: 29310095
risk_code: 36/38-21-52-41
化審法: (2)-2071
消防法: 危-4-3-III
hazard_code: Xn,Xi
safety_code: 28A-26-36/37/39-24/25
packing_group: III
自然発火温度: 400°C
Hazard Classifications: Aquatic Chronic 3Eye Dam. 1
ストレージクラス: 10 - Combustible liquids

化学と産業

用途と製造

Uses · 2 件

Used as additive (cross-linking agent) for adhesion promotion in adhesives, sealants, coatings, and composites; Used in reinforcing glass fibers and foundry resins; [eChemPortal: SIDSUNEP]

Molding and Core Making [Category: Foundry]

U.S. Production2023: 2,500,000 - <4,000,000 lb

Consumer UsesAntioxidant

Industry UsesSizing agent

Household ProductsInformation on 3 consumer products that contain gamma-Glycidoxypropyltrimethoxysilane in the following categories is provided:

General Manufacturing Information · 2 件

All Other Chemical Product and Preparation Manufacturing

Oxirane, 2-[[3-(trimethoxysilyl)propoxy]methyl]-: ACTIVE

応用分野 · 2 件

使用Pre-treatment of carbon steel with 3-(Glycidoxypropyl)trimethoxysilane enhances the dry and wet adhesion while reducing the cathotic disbondment rate of an epoxy coating

一般的な説明(3-Glycidyloxypropyl)trimethoxysilane (GPTMS) is a bifunctional organosilane with three methoxy groups on one side and an epoxy ring on the other. The methoxy groups bind well with glass substrates creating a 3D matrix. The epoxy group is reactive with amides, alcohols, thiols and acids. GPTMS is highly reactive in water and can be used as a linking agent between the surface of the silica and the polymeric matrix.