エタンシラート

Etamsylate

HCID 17506CAS 2624-44-4

基本情報

標準SMILES
CCNCC.O=S(=O)(O)c1cc(O)ccc1O
InChIKey
HBGOLJKPSFNJSD-UHFFFAOYSA-N
分子式
C10H17NO5S
平均分子量
263.31 g/mol
単同位体質量
263.08274382

名称と識別子

優先名称
Etamsylate
IUPAC
2,5-dihydroxybenzenesulfonic acid;N-ethylethanamine
現地名
エタンシラート
英語名
Etamsylate
分子式
C10H17NO5S
分子量
263.31

名称と別名

EtamsylateETHAMSYLATE2624-44-4CyclonamineDicyneneEtamsilatoEtamsylatumEtamsilateMD 141E 141Diethylamine dobesilateDTXSID4045559
名称をさらに表示
ジエチルアミン·2,5-ジヒドロキシベンゼンスルホン酸エタムシラートジシネンアグルミンアルトドルエセリン【止血薬】エタンシラートシクロナミンジエチルアミン 2,5-ジヒドロキシベンゼンスルホン酸塩エタンシラート (JAN)Phenolsulfonatee141md141eselinHeMsylK-StatSylatealtodoraglumin
24YL531VOHMD-141DTXCID2025559E-141Dicynene 1000RefChem:55154B02BX012,5-dihydroxybenzene-1-sulfonic acid; diethylamine

データベース識別子

CAS
2624-44-4
PubChem CID
17506
DTXSID
DTXSID4045559
ChEMBL
CHEMBL1514715
ChEBI
CHEBI:31563
UNII
24YL531VOH
EC Number
220-090-7

物性

構造計算による物性

極性表面積
115 Ų
水素結合供与体数
4
水素結合受容体数
6
回転可能結合数
3
重原子数
17

物理化学的性質

融点
125 ° · 125°
比重(密度)
1.3441 · 1.3441 (rough estimate)
屈折率
1.506 · 1.5060 (estimate)
貯蔵温度
Keep in dark place,Inert atmosphere,Room temperature
溶解性
水に易溶、メタノールに易溶、無水エタノールに易溶、ジクロロメタンにほとんど溶けない。
外見
Solid

化学的性質

化学的特性White Solid

安全と法規制

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 12.2% (5 of 41) of reports.

Warning

H319 (85.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement)

Aggregated GHS information provided per 41 reports by companies from 3 notifications to the ECHA C&L Inventory.;Reported as not meeting GHS hazard criteria per 5 of 41 reports by companies.;There are 2 notifications provided by 36 of 41 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Regulatory InformationChemical: Benzenesulfonic acid, 2,5-dihydroxy-, compound with N-ethylethanamine (1:1)
Other Safety InformationEvaluation - Chemicals not considered for in depth evaluation - Not commercially active in Australia
Hazard Classes and CategoriesEye Irrit. 2 (85.4%)

法規制情報

Regulatory InformationChemical: Benzenesulfonic acid, 2,5-dihydroxy-, compound with N-ethylethanamine (1:1)

安全データ

wgk
WGK 3
tsca
TSCA listed
rtecs
DB6145000
毒性
LD50 i.v. in mice, rats: 800, 1350 mg/kg (Esteve)
hs_code
2921.19.6190
hazard_class
IRRITANT

化学と産業

薬理情報

ATC Code · 3 件

B02BX01

B - Blood and blood forming organs;B02 - Antihemorrhagics;B02B - Vitamin k and other hemostatics;B02BX - Other systemic hemostatics;B02BX01 - Etamsylate

QB - Blood and blood forming organs;QB02 - Antihemorrhagics;QB02B - Vitamin k and other hemostatics;QB02BX - Other systemic hemostatics;QB02BX01 - Etamsylate

MeSH Pharmacological Classification · 1 件

Agents acting to arrest the flow of blood. Absorbable hemostatics arrest bleeding either by the formation of an artificial clot or by providing a mechanical matrix that facilitates clotting when applied directly to the bleeding surface. These agents function more at the capillary level and are not effective at stemming arterial or venous bleeding under any significant intravascular pressure.

用途と製造

General Manufacturing InformationBenzenesulfonic acid, 2,5-dihydroxy-, compd. with N-ethylethanamine (1:1): INACTIVE

応用分野

使用Hemostatic;prostaglandin synthesis inhibitor

サプライヤー50 社

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Shanghai Biolang Biotechnology Co., Ltd.+86-15970428662 +86-13397199602 · [email protected]
Baoji Guokang Healthchem co.,ltd+8615604608665 15604608665 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
Jai Radhe Sales+(91)-(79)-26431096/65255722 · [email protected]

関連反応

3 件

関連ノート

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