基本情報
- CAS
98717-15-8- 標準SMILES
CCCN1CCCC[C@H]1C(=O)Nc1c(C)cccc1C.Cl- InChIKey
NDNSIBYYUOEUSV-RSAXXLAASA-N- 分子式
- C17H27ClN2O
- 平均分子量
- 310.9 g/mol
- 単同位体質量
- 310.1811912
名称と識別子
- 優先名称
- Ropivacaine Hydrochloride
- IUPAC
- (2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide;hydrochloride
- 現地名
- ロピバカイン塩酸塩
- 英語名
- Ropivacaine hydrochloride
- 分子式
- C17H26N2O.ClH
- 分子量
- 310.86
名称と別名
Ropivacaine hydrochlorideROPIVACAINE HCl98717-15-8Ropivacaine monohydrochlorideDTXSID204837935504LBE2TDTXCID2028353ROPIVACAINE HYDROCHLORIDE [MI]ROPIVACAINE HYDROCHLORIDE [MART.]ROPIVACAINE HYDROCHLORIDE ANHYDROUSROPIVACAINE HYDROCHLORIDE [WHO-DD]2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-, monohydrochloride, (S)-
名称をさらに表示
ロピバカイン塩酸塩S-ROPIVACAINE HCLRopivacaine mesilateRopivacaine hydrochlROPIVCACAINE HYDROCHLORIDERopivacaine HCl (anhydrous)(S)-ROPIVACAINE HYDROCHLORIDE
(S)-(-)-1-PROPYL-2',6'-PIPECOLOXYLIDINE HYDROCHLORIDE(S)-(-)-1-PROPYLPIPERIDINE-2-CARBOXYLIC ACID (2,6-DIMETHYLPHENYL)AMIDE HYDROCHLORIDEROPIVACAINE HYDROCHLORIDE (MART.)ROPIVACAINE HYDROCHLORIDE [VANDF]ROPIVACAINE HYDROCHLORIDE [ORANGE BOOK]ROPIVACAINE HYDROCHLORIDE (USP MONOGRAPH)ROPIVACAINE HYDROCHLORIDE [USP MONOGRAPH]ROPIVACAINE HYDROCHLORIDE MONOHYDRATE [MI]
データベース識別子
- CAS
98717-15-8- PubChem CID
- 175804
- DTXSID
DTXSID2048379- ChEMBL
CHEMBL1889140- UNII
- 35504LBE2T
- EC Number
- 691-259-4
物性
構造計算による物性
- 極性表面積
- 32.3 Ų
- 水素結合供与体数
- 2
- 水素結合受容体数
- 2
- 回転可能結合数
- 4
- 重原子数
- 21
- 形式電荷
- 0
- 複雑度
- 308
物理化学的性質
- 融点
- 260 · 260-262°
- 比旋光度
- 25 · D25 -6.6° (c = 2 in water)
- 貯蔵温度
- -20 °C · Store at -20°C
- 外見
- Solid
- 色
- White to off-white
- 水溶解度
- 10.1 mg/mL · ≥ 10.1mg/mL in Water
- 主な用途
- 医薬品低分子化合物
- InChI
- InChI=1S/C17H26N2O.ClH/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3;/h7-9,15H,4-6,10-12H2,1-3H3,(H,18,20);1H
- InChIKey
- NDNSIBYYUOEUSV-UHFFFAOYSA-N
- SMILES
- N1(CCC)CCCCC1C(NC1=C(C)C=CC=C1C)=O.[H]Cl
- CAS データベース
- 98717 · 98717-15-8(CAS DataBase Reference)
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
GHS分類
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]；H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]；H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]；H412 (100%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]
P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
安全データ
- wgk
- WGK 3
- Hazard Classifications
- Eye Dam. 1
- ストレージクラス
- 13 - Non Combustible Solids
化学と産業
薬理情報
FDA Pharmacological Classification
ROPIVACAINE HYDROCHLORIDE
Amide Local Anesthetic [EPC]; Amides [CS]; Local Anesthesia [PE]
MeSH Pharmacological Classification
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.
応用分野
使用anesthetic
上流・下流製品情報
下流製品
サプライヤー101 社
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
河南赢创生物科技有限公司16650615803 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
普善实业（陕西）有限公司029-81310890 18165209495 · [email protected]
関連反応
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化合物ノート
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