基本情報
- CAS
124223-99-0- 標準SMILES
CC(=O)N[C@H]1[C@@H](Oc2ccc3c(C)cc(=O)oc3c2)O[C@H](CO)[C@H](O)[C@@H]1O- InChIKey
QCTHLCFVVACBSA-LHKMKVQPSA-N- 分子式
- C18H21NO8
- 平均分子量
- 379.4 g/mol
- 単同位体質量
- 379.12671663
名称と識別子
- 優先名称
- 4-Methylumbelliferyl 2-acetamido-2-deoxy-alpha-D-galactopyranoside
- IUPAC
- N-[(2R,3R,4R,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(4-methyl-2-oxochromen-7-yl)oxyoxan-3-yl]acetamide
- 英語名
- 4-METHYLUMBELLIFERYL 2-ACETAMIDO-2-DEOXY-ALPHA-D-GALACTOPYRANOSIDE
- 分子式
- C18H21NO8
- 分子量
- 379.36
名称と別名
124223-99-04-METHYLUMBELLIFERYL 2-ACETAMIDO-2-DEOXY-ALPHA-D-GALACTOPYRANOSIDEMFCD002700474-Methylumbelliferyl 2-acetamido-2-deoxy-|A-D-galactopyranosideN-[(2R,3R,4R,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(4-methyl-2-oxochromen-7-yl)oxyoxan-3-yl]acetamide4-Methylumbelliferyl 2-acetamido-2-deoxy--D-galactopyranosideC18H21NO8orb2941063SCHEMBL4256121TXB-00052EM04782s11465
名称をさらに表示
4MU-α-GalNAcGalNAc-α-4MUGalNAc1-α-4MUGalNAc-alpha-4MU4-Methylumbelliferyl 2-Acetamido-2-deoxy-α-D-galactopyranoside7-[[2-(AcetylaMino)-2-deoxy-α-D-galactopyranosyl]oxy]-4-Methyl-4-Methylumbelliferyl 2-Acetamido-2-deoxy-α-D-galactopyranoside+.0、‘’、7-[[2-(Acetylamino)-2-deoxy-a-D-galactopyranosyl]oxy]-4-methyl-2H-1-benzopyran-2-one2H-1-Benzopyran-2-one, 7-[[2-(acetylamino)-2-deoxy-α-D-galactopyranosyl]oxy]-4-methyl-4-Methylumbelliferyl 2-acetamido-2-deoxy-a-D-galactopyranoside - Moscerdam biochemical purity
PD080449CS-00798254-Methylumbelliferyl 2-acetamido-2-deoxy-I<<-D-galactopyranoside7-[[2-(Acetylamino)-2-deoxy-alpha-D-galactopyranosyl]oxy]-4-methyl-2H-1-benzopyran-2-one2H-1-Benzopyran-2-one, 7-[[2-(acetylamino)-2-deoxy-alpha-D-galactopyranosyl]oxy]-4-methyl-4-Methylumbelliferyl 2-acetamido-2-deoxy-a-D-galactopyranoside - Moscerdamtrade mark biochemical purityN-[(2R,3R,4R,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(4-methyl-2-oxo-chromen-7-yl)oxy-tetrahydropyran-3-yl]acetamide
データベース識別子
- CAS
124223-99-0- PubChem CID
- 14345477
物性
構造計算による物性
- XLogP
- -0.8
- 極性表面積
- 135 Ų
- 水素結合供与体数
- 4
- 水素結合受容体数
- 8
- 回転可能結合数
- 4
- 重原子数
- 27
- 形式電荷
- 0
- 複雑度
- 608
物理化学的性質
- 融点
- 257 · 257-260°C
- 沸点
- 732.2 · 732.2±60.0 °C(Predicted)
- 比重(密度)
- 1.47 · 1.47±0.1 g/cm3(Predicted)
- 貯蔵温度
- -20 °C · -20°C Freezer
- 溶解性
- DMSO（微量）、メタノール（微量、加温）
- 外見
- 個体
- 酸解離定数(Pka)
- 12.87 · 12.87±0.70(Predicted)
- 色
- ホワイトからオフホワイト
- CAS データベース
- 124223 · 124223-99-0
化学的性質
化学的特性Off-White Solid
化学と産業
応用分野
説明4-Methylumbelliferyl 2-acetoamido-2-deoxy-α-D-galactopyranoside (4-MU-2-acetoamido-2-deoxy-α-Gal) is a fluorogenic substrate used to quantify α- and β-galactopyranosaminidase activity. 4-MU-2-acetoamido-2-deoxy-α-Gal is cleaved by α- and β-galactopyranosaminidase to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases.
使用An effective substrate for the detection of N-acetyl-a-D-Galactopyranosiaminidase activity. The deficiency of this enzyme is the defect in Schindler disease
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